Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

APOC4 (P55056) - Overview - Molecular Target Synopsis

Protein


APOC4, Apolipoprotein C-IV
UniProt P55056

Also Known as APOC4_HUMAN, APOC4

May participate in lipoprotein metabolism.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: APOC4 is active in the following subcellular-locations: secreted.
GO terms: APOC4 is active in the following subcellular-locations: extracellular region, high-density lipoprotein particle, very-low-density lipoprotein particle.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project APOC4 has gain in 4 cell-lines, loss in 0 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: KM12, IGROV1, HL_60

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)