Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

CBK1 (P53894) - Overview - Molecular Target Synopsis

Protein


CBK1, Serine/threonine-protein kinase CBK1
Enzyme Classification 2.7.11.1
UniProt P53894

Also Known as CBK1_YEAST, CBK1

Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation. Associates with PAG1/TAO3 and interacts with MOB2.

6G85
10 RESIDUE FRAGMENT OF
CBK1
IN THE STRUCTURE OF
STRUCTURE OF CDC14 BOUND TO CBK1 PXL MOTIF
RCSB/PDB
Inspect Structure
See all 3D Structures for CBK1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
756P53894-1

Sub-cellular localization


Gene Copy Number Variation


In COSMIC - Cell Lines Project CBK1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For CBK1 there are:
7 structures (10 chains) solved
4 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


CBK1 has been screened with compounds ( bioactivities). (see details)