Molecular Target Synopsis
Overview
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METAP1 (P53582) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 1Y1N_A 48.93 2.0E-71 1.51Å - 2005-05-24
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4IKT_A 100 0 1.6Å TFV 2013-12-11
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2EVM_A 46.54 5.0E-64 1.7Å FC2 2006-03-28
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 4Z7M_A 46.54 6.0E-64 1.43Å 4L9 2016-04-13
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U75_A 100 0 1.93Å MET 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO8_B 51.97 1.0E-73 1.9Å MET 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2EVC_A 46.54 5.0E-64 1.6Å FC3 2006-03-28
Metallopeptidase family M24 (100%) (view alignment) map (Q9ZCD3) - 3MR1_A 43.55 1.0E-61 2Å - 2010-05-26
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO7_B 51.97 1.0E-73 1.8Å - 2013-07-03
Metallopeptidase family M24 (91%) (view alignment) (B1MGB2) - 3TAV_B 36.16 1.0E-34 2.15Å - 2011-08-17
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2B3H_A 100 0 1.1Å - 2005-11-22
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3PKA_A 48.93 2.0E-71 1.25Å Y02 2011-04-20
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U73_A 100 0 1.8Å Q02 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 4MAT_A 46.54 7.0E-64 2Å - 1999-06-18
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3PKC_A 48.93 2.0E-71 1.47Å Y08 2011-04-20
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U6W_A 100 0 1.8Å Q08 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2B3K_A 100 0 1.55Å - 2005-11-22
Metallopeptidase family M24 (100%) (view alignment) (A0A140NFG5) - 4A6V_B 46.54 5.0E-64 1.46Å IKY 2012-06-13
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 5YR7_A 100 0 2.05Å MET 2018-11-14
Metallopeptidase family M24 (100%) (view alignment) map (Q9ZCD3) - 3MX6_A 43.14 8.0E-62 1.7Å MET 2010-05-26
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3ROR_A 48.57 1.0E-70 2Å - 2012-05-23
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2EVO_B 46.54 5.0E-64 1.7Å CT0 2006-03-28
Metallopeptidase family M24 (100%) (view alignment) map (Q9ZCD3) - 3MR1_C 43.55 1.0E-61 2Å - 2010-05-26
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2G6P_A 100 0 1.77Å EPE HM2 2006-06-20
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO7_D 51.97 1.0E-73 1.8Å - 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU5_A 46.88 1.0E-63 1.6Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (P9WK18) - 4OOK_A 48.93 1.0E-71 1.9Å - 2015-02-04
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 4IDY_A 48.93 2.0E-71 2Å HED 2013-12-18
Metallopeptidase family M24 (100%) (view alignment) (A5U6L5) - 5YPD_A 48.57 9.0E-71 1.62Å MET 2018-11-07
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 5YR5_A 100 0 1.6Å OVA 2018-11-14
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1C22_A 46.54 6.0E-64 1.75Å MF3 1999-11-17
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1C27_A 46.54 6.0E-64 1.95Å NLP 1999-11-17
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1XNZ_A 46.54 5.0E-64 1.52Å FCD 2004-11-02
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3IU9_A 48.93 1.0E-71 1.75Å T07 2010-01-12
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG3_A 46.54 6.0E-64 1.45Å U13 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U76_A 100 0 1.87Å - 2015-03-25
zf-MYND-like zinc finger, mRNA-binding (100%), Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4IU6_A 100 0 1.9Å FZ1 2013-05-01
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4IKU_A 100 0 1.3Å SHX 2013-12-11
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3IU7_A 48.93 1.0E-71 1.4Å FCD 2010-01-12
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2B3L_A 100 0 1.5Å - 2005-11-22
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U6Z_A 100 0 1.8Å Q07 2015-04-15
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG7_A 46.54 6.0E-64 1.12Å U14 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU7_A 46.88 1.0E-63 2Å - 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U6E_A 100 0 1.85Å Q02 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4JUQ_C 51.76 1.0E-73 2.2Å - 2014-04-30
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3PKE_A 48.93 2.0E-71 1.6Å Y10 2011-04-20
Metallopeptidase family M24 (100%) (view alignment) (Q9X1I7) - 1O0X_A 36.69 8.0E-46 1.9Å - 2002-11-06
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG0_A 46.54 6.0E-64 1.28Å U11 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GTX_A 46.88 2.0E-63 2Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) (A5U6L5) - 5YOH_A 48.57 6.0E-71 1.62Å MET 2018-11-07
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U69_A 100 0 1.57Å Q07 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U1B_A 100 0 1.89Å Q08 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GGC_A 46.54 6.0E-64 1Å MET 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) (A0A140NFG5) - 4A6W_A 46.54 5.0E-64 1.46Å 5C1 2012-06-13
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) tig (Q9WZF8) 6J0A_P 46.54 5.0E-64 14.2Å - 2019-04-17
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4FLK_A 100 0 1.47Å Y10 2012-09-19
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU6_B 46.88 1.0E-63 1.7Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 6IZ7_P 46.54 5.0E-64 11.8Å - 2019-04-17
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 4IF7_A 48.93 2.0E-71 2Å SCH HCM 2013-12-18
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU5_B 46.88 1.0E-63 1.6Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2MAT_A 46.54 5.0E-64 1.9Å - 1999-06-18
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GTX_B 46.88 2.0E-63 2Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 1YJ3_A 48.93 2.0E-71 1.6Å MET 2005-07-05
Metallopeptidase family M24 (100%) (view alignment) map (Q9ZCD3) - 3MX6_B 43.14 8.0E-62 1.7Å MET 2010-05-26
Metallopeptidase family M24 (100%) (view alignment) (A5U6L5) - 5YPJ_A 48.57 9.0E-71 2.01Å - 2018-11-07
Metallopeptidase family M24 (100%) (view alignment) (Q4FKC0) - 4FUK_B 53.65 8.0E-97 1.75Å - 2012-08-29
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2Q94_A 46.54 6.0E-64 1.63Å A04 2008-01-01
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 5YR6_A 100 0 1.75Å TN4 2018-11-14
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4HXX_A 100 0 2.09Å 1AY 2013-04-03
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 3D27_A 46.88 2.0E-63 2.2Å W29 2008-08-19
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3PKD_A 48.93 2.0E-71 1.47Å Y10 2011-04-20
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2NQ6_A 100 0 1.5Å HM4 2006-11-21
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2P9A_A 46.54 6.0E-64 1.6Å YE6 2007-11-20
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) def (P0A6K3) 6IZI_Q 46.54 5.0E-64 11.8Å - 2019-04-17
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4JUQ_D 51.76 1.0E-73 2.2Å - 2014-04-30
Metallopeptidase family M24 (91%) (view alignment) (B1MGB2) - 3TAV_A 36.16 1.0E-34 2.15Å LMR MLT 2011-08-17
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1C21_A 46.54 6.0E-64 1.8Å MET 1999-11-17
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1C24_A 46.54 6.0E-64 1.7Å MPJ 1999-11-17
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO8_A 51.97 1.0E-73 1.9Å MET 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2Q95_A 46.54 6.0E-64 1.7Å A05 2008-01-01
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2Q92_A 46.54 6.0E-64 1.9Å B23 2008-01-01
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU4_A 46.88 1.0E-63 1.8Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1MAT_A 46.54 5.0E-64 2.4Å - 1994-01-31
Metallopeptidase family M24 (100%) (view alignment) map (Q9ZCD3) - 3MR1_B 43.55 1.0E-61 2Å - 2010-05-26
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2NQ7_A 100 0 1.6Å HM5 2006-11-21
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U71_A 100 0 1.8Å Q03 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU7_B 46.88 1.0E-63 2Å - 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (Q9ZCD3) - 3MR1_D 43.55 1.0E-61 2Å - 2010-05-26
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3PKB_A 48.93 2.0E-71 1.25Å Y16 2011-04-20
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1C23_A 46.54 6.0E-64 2Å MPH 1999-11-17
Metallopeptidase family M24 (100%) (view alignment) (V5VCW7) - 6MRF_A 42.97 4.0E-52 1.65Å - 2018-10-31
Metallopeptidase family M24 (100%) (view alignment) (C3TPN7) - 4PNC_A 46.54 5.0E-64 1.54Å 7NP 2014-07-23
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GGB_A 46.54 6.0E-64 2.13Å U17 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) (Q8IJP2) - 3S6B_A 53.59 1.0E-96 1.9Å - 2011-06-29
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO7_C 51.97 1.0E-73 1.8Å - 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG5_A 46.54 6.0E-64 2.12Å U19 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2Q93_A 46.54 6.0E-64 1.6Å B21 2008-01-01
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 5YKP_A 100 0 1.67Å OVA 2018-10-17
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2P99_A 46.54 6.0E-64 1.8Å YE6 2007-11-20
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG2_A 46.54 6.0E-64 1Å U12 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO8_C 51.97 1.0E-73 1.9Å MET 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO8_D 51.97 1.0E-73 1.9Å MET 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU6_A 46.88 1.0E-63 1.7Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2EVO_A 46.54 5.0E-64 1.7Å CT0 2006-03-28
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4JUQ_B 51.76 1.0E-73 2.2Å - 2014-04-30
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2BB7_A 46.54 5.0E-64 1.7Å QMS 2006-01-24
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4JUQ_A 51.76 1.0E-73 2.2Å - 2014-04-30
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4FLJ_A 100 0 1.74Å Y08 2012-09-19
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U6J_A 100 0 1.56Å MET 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) (A5U6L5) - 5YOI_A 48.57 5.0E-71 1.63Å MET 2018-11-07
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4FLL_A 100 0 1.5Å YZ6 2012-09-19
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GU4_B 46.88 1.0E-63 1.8Å NLP 2006-07-04
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4IKR_A 100 0 1.78Å PVP 2013-12-11
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG8_A 46.54 6.0E-64 1.8Å U15 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2GG9_A 46.54 6.0E-64 1.05Å U16 2006-06-13
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U6C_A 100 0 1.87Å Q06 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) (A5U6L5) - 5YXF_A 48.57 6.0E-71 1.61Å MET 2018-12-12
Metallopeptidase family M24 (100%) (view alignment) (Q9HXY1) - 4FO7_A 51.97 1.0E-73 1.8Å - 2013-07-03
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 4IEC_A 48.93 2.0E-71 2Å - 2013-12-18
Metallopeptidase family M24 (100%) (view alignment) (A0A140NFG5) - 4A6V_A 46.54 5.0E-64 1.46Å IKY 2012-06-13
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 2GZ5_A 100 0 1.1Å OVA 2006-05-23
Metallopeptidase family M24 (100%) (view alignment) (Q4FKC0) - 4FUK_A 53.65 8.0E-97 1.75Å - 2012-08-29
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2P98_A 46.54 6.0E-64 1.7Å YE7 2007-11-20
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 1YVM_A 46.54 5.0E-64 1.6Å TMG 2005-06-07
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4U70_A 100 0 1.6Å Q04 2015-03-25
Metallopeptidase family M24 (100%) (view alignment) map (P9WK19) - 3IU8_A 48.93 1.0E-71 1.85Å T03 2010-01-12
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 4Z7M_B 46.54 6.0E-64 1.43Å 4L9 2016-04-13
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 2Q96_A 46.54 6.0E-64 1.6Å A18 2008-01-01
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4IKS_A 100 0 1.7Å TFD 2013-12-11
Metallopeptidase family M24 (100%) (view alignment) map (P0AE18) - 3MAT_A 46.54 6.0E-64 2Å - 1999-06-18
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 5YR4_A 100 0 1.82Å TN4 2018-11-14
Metallopeptidase family M24 (100%) (view alignment) METAP1 (P53582) - HUMAN 4FLI_A 100 0 1.55Å Y16 2012-09-19