Molecular Target Synopsis
Overview
Domains and Structures
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Ligand Efficiency Plot
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AFF1 (P51825) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
AF-4 proto-oncoprotein (4%) (view alignment) AFF1 (P51825), MLLT3 (P42568) - HUMAN 2LM0_A 100 0 - 2013-01-09
AF-4 proto-oncoprotein (6%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563), tat (P69698) HUMAN 4OGR_G 61.19 4.0E-18 3Å - 2014-05-07
AF-4 proto-oncoprotein (5%) (view alignment) AFF4 (Q9UHB7) ELL2 (O00472) HUMAN 5JW9_A 72.55 1.0E-16 2Å - 2017-02-08
AF-4 proto-oncoprotein (6%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563) HUMAN 4IMY_H 61.19 4.0E-18 2.94Å - 2013-03-13
AF-4 proto-oncoprotein (6%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563) HUMAN 4IMY_G 61.19 4.0E-18 2.94Å - 2013-03-13
AF-4 proto-oncoprotein (6%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563), tat (P69698) HUMAN 4OGR_C 61.19 4.0E-18 3Å - 2014-05-07
AF-4 proto-oncoprotein (22%) (view alignment) AFF4 (Q9UHB7) - HUMAN 6R80_A 42.08 1.0E-43 2.2Å - 2019-06-12
AF-4 proto-oncoprotein (6%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563) HUMAN 4IMY_I 61.19 4.0E-18 2.94Å - 2013-03-13
AF-4 proto-oncoprotein (6%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563), tat (P69698) HUMAN 4OGR_L 61.19 4.0E-18 3Å - 2014-05-07