Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

TPMT (P51580) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) Tpmt (O55060) - MOUSE 3BGI_A 77.78 1.0E-114 1.8Å SAH 2008-06-10
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) Tpmt (O55060) - MOUSE 3BGD_B 77.78 1.0E-114 2Å PM6 SAH 2008-06-10
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) TPMT (P51580) - HUMAN 2H11_A 100 0 1.89Å SAH B3P 2006-11-21
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) Tpmt (O55060) - MOUSE 3BGD_A 77.78 1.0E-114 2Å PM6 SAH 2008-06-10
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) Tpmt (O55060) - MOUSE 3BGI_B 77.78 1.0E-114 1.8Å SAH 2008-06-10
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) Tpmt (O55060) - HOUSE MOUSE 2GB4_A 78.66 8.0E-114 1.25Å SAH 2006-09-19
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) TPMT (P51580) - HUMAN 2BZG_A 100 0 1.58Å SAH B3P 2005-08-25
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) TPMT (P51580) - HUMAN 2H11_B 100 0 1.89Å SAH B3P 2006-11-21
Thiopurine S-methyltransferase (TPMT) (100%) (view alignment) Tpmt (O55060) - HOUSE MOUSE 2GB4_B 78.66 8.0E-114 1.25Å SAH 2006-09-19