Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

METAP2 (P50579) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 6QED_A 100 0 1.8Å HZK 2019-05-01
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1WKM_B 38.59 8.0E-49 2.3Å MET 2005-02-22
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1YW9_A 100 0 1.64Å A84 2006-02-21
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1B6A_A 100 0 1.58Å TN4 2000-01-13
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGO_A 38.59 8.0E-49 3.5Å - 1998-02-25
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 2DFI_B 38.59 1.0E-48 2Å - 2007-03-06
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 2ADU_A 100 0 1.9Å R20 2005-09-13
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1KQ9_A 100 0 1.9Å MET 2003-12-09
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 6QEI_A 100 0 1.8Å HZE 2019-05-01
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5D6E_A 100 0 1.49Å 94A 2016-01-13
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGM_A 38.59 8.0E-49 2.8Å - 1998-02-25
Metallopeptidase family M24 (100%) (view alignment) MAP2 (Q8SR45) - 3FMQ_A 43.87 5.0E-73 2.5Å FUG 2009-01-13
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 2GA2_A 100 0 1.95Å A19 2007-03-13
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGM_B 38.59 8.0E-49 2.8Å - 1998-02-25
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1R58_A 100 0 1.9Å AO5 2004-10-12
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 2EA4_A 100 0 2.35Å F79 2008-02-05
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1BN5_A 100 0 1.8Å - 1999-07-31
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1KQ0_A 100 0 2Å MED 2003-12-09
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1BOA_A 100 0 1.8Å FUG 1999-08-01
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGS_B 38.59 8.0E-49 1.75Å - 1997-07-07
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5JFR_A 100 0 1.6Å 6KP 2016-05-25
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 2EA2_A 100 0 2.5Å F77 2008-02-05
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5CLS_A 100 0 1.75Å 52T 2016-01-13
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 2OAZ_A 100 0 1.9Å I96 2007-06-19
Metallopeptidase family M24 (100%) (view alignment) MAP2 (Q8SR45) - 3FMQ_B 43.87 5.0E-73 2.5Å FUG 2009-01-13
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 6QEG_A 100 0 2.08Å K4K 2019-05-01
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 6QEF_A 100 0 1.79Å HZW 2019-05-01
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1R5H_A 100 0 2.4Å AO2 2004-10-12
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5LYW_A 100 0 1.6Å 7BH 2017-08-16
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1WKM_A 38.59 8.0E-49 2.3Å MET 2005-02-22
Metallopeptidase family M24 (100%) (view alignment) MAP2 (Q8SR45) - 3FM3_B 43.87 5.0E-73 2.18Å - 2009-01-13
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGN_B 38.59 8.0E-49 2.9Å - 1998-02-25
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 6QEH_A 100 0 2.17Å HZQ 2019-05-01
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1YW7_A 100 0 1.85Å A41 2006-02-21
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1R5G_A 100 0 2Å AO1 2004-10-12
Metallopeptidase family M24 (100%) (view alignment) MAP2 (Q8SR45) - 3FMR_A 43.87 5.0E-73 2.89Å TN4 2009-01-13
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5D6F_A 100 0 1.55Å 57R 2016-01-13
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1QZY_A 100 0 1.6Å TDE 2003-11-25
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 6QEJ_A 100 0 1.62Å HZT 2019-05-01
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGN_A 38.59 8.0E-49 2.9Å - 1998-02-25
Metallopeptidase family M24 (100%) (view alignment) MAP2 (Q8SR45) - 3FM3_A 43.87 5.0E-73 2.18Å - 2009-01-13
Metallopeptidase family M24 (100%) (view alignment) MAP2 (Q8SR45) - 3FMR_B 43.87 5.0E-73 2.89Å TN4 2009-01-13
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 1XGS_A 38.59 8.0E-49 1.75Å - 1997-07-07
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5JI6_A 100 0 2.15Å 6KN 2016-05-25
Metallopeptidase family M24 (99%) (view alignment) map (P56218) - 2DFI_A 38.59 1.0E-48 2Å - 2007-03-06
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1B59_A 100 0 1.8Å OVA 2000-01-14
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5JHU_A 100 0 1.7Å 6KO 2016-05-25
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 1YW8_A 100 0 2.65Å A75 2006-02-21
Metallopeptidase family M24 (100%) (view alignment) METAP2 (P50579) - HUMAN 5LYX_A 100 0 1.9Å 7BF 2017-08-16