Molecular Target Synopsis
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FASN (P49327) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY2_C 87.07 0 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5E6K_B 35.53 5.0E-68 -
Zinc-binding dehydrogenase (100%) (view alignment) FASN (P49327) - 4W82_B 100 0 -
Phosphopantetheine attachment site (100%) (view alignment) Fasn (P12785) - 2PNG_A 77.01 3.0E-22 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY2_A 87.07 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY2_D 87.07 0 COA
Zinc-binding dehydrogenase (100%) (view alignment) FASN (P49327) - 4W9N_B 100 0 TCL
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFD_D 100 0 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5E5N_B 35.53 5.0E-68 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (43%) (view alignment) FASN (P49327) - 3HHD_D 100 0 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5E5N_C 35.53 5.0E-68 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5E6K_A 35.53 5.0E-68 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksJ (P40806) - 4NA2_B 35.71 1.0E-68 2JF
Thioesterase domain (100%) (view alignment) FASN (P49327) - 2PX6_B 100 0 DH9
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ERF_A 35.76 4.0E-69 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) eryA (Q03132) - 2QO3_A 37.47 1.0E-17 CER
Polyketide synthase dehydratase (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%) (view alignment) - 6FN6_B 53.79 2.0E-55 -
Zinc-binding dehydrogenase (100%) (view alignment) FASN (P49327) - 4W82_A 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (100%), Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%), Phosphopantetheine attachment site (100%), Thioesterase domain (100%) (view alignment) (A5YV76) - 2VZ9_B 78.68 0 NAP
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5E5N_A 35.53 5.0E-68 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (43%) (view alignment) FASN (P49327) - 3HHD_B 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksJ (P40806) - 4NA2_A 35.71 1.0E-68 2JF
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5E5N_D 35.53 5.0E-68 -
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFK_B 100 0 COA MCS
Thioesterase domain (100%) (view alignment) FASN (P49327) - 2PX6_A 100 0 DH9
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFK_A 100 0 COA MCS
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) eryA (Q03132) - 2QO3_B 37.47 1.0E-17 CER
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_G 35.76 1.0E-69 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY0_D 87.07 0 COA K5L
Zinc-binding dehydrogenase (100%) (view alignment) ppsC (P96202) - 1PQW_A 39.3 3.0E-32 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (Q1RS72) - 5ERB_D 38.95 2.0E-76 -
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFK_C 100 0 COA MCS
Thioesterase domain (100%) (view alignment) FASN (P49327) - 3TJM_A 100 0 7FA
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (D0U2E4) - 4TKT_A 36.32 4.0E-61 MES
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (B2WW42) - 4OPE_B 38.48 1.0E-67 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (D0U2E4) - 4ZDN_A 37.21 8.0E-69 EPE
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (43%) (view alignment) FASN (P49327) - 3HHD_A 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (Q1RS72) - 5ERB_C 38.95 2.0E-76 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksJ (P40806) - 4NA1_A 35.94 6.0E-70 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksJ (P40806) - 4NA3_B 35.71 1.0E-68 2JG
Zinc-binding dehydrogenase (100%) (view alignment) FASN (P49327) - 4W9N_D 100 0 TCL
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksJ (P40806) - 4NA1_B 35.94 6.0E-70 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_H 35.76 1.0E-69 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (B2WW42) - 4OPE_C 38.48 1.0E-67 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (43%) (view alignment) FASN (P49327) - 3HHD_C 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (B2WW42) - 4OPE_A 38.48 1.0E-67 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_C 35.76 1.0E-69 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY0_B 87.07 0 -
Zinc-binding dehydrogenase (100%) (view alignment) FASN (P49327) - 4W9N_A 100 0 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_A 35.76 1.0E-69 -
Thioesterase domain (100%) (view alignment) FASN (P49327) - 4Z49_B 100 0 -
Zinc-binding dehydrogenase (100%) (view alignment) ppsC (P96202) - 4OKI_B 39.29 3.0E-31 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (Q1RS72) - 5ERB_A 38.95 2.0E-76 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (B2WW42) - 4OPE_D 38.48 1.0E-67 -
Polyketide synthase dehydratase (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%) (view alignment) - 6FN6_A 53.79 2.0E-55 -
Thioesterase domain (100%) (view alignment) FASN (P49327) - 4Z49_A 100 0 -
Zinc-binding dehydrogenase (100%) (view alignment) ppsC (P96202) - 1PQW_B 39.3 3.0E-32 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ERF_B 35.76 4.0E-69 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY0_C 87.07 0 MLC
Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%) (view alignment) FASN (P49327) - 6NNA_A 100 0 KUA CAF NDP
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (C0ZGQ5) - 4Z37_A 35.47 2.0E-64 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (100%), Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%), Phosphopantetheine attachment site (100%), Thioesterase domain (100%) (view alignment) (A5YV76) - 2VZ9_A 78.68 0 NAP
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFK_D 100 0 COA MCS
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_F 35.76 1.0E-69 -
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFD_B 100 0 -
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_B 35.76 1.0E-69 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (100%), Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%), Phosphopantetheine attachment site (100%), Thioesterase domain (100%) (view alignment) (A5YV76) - 2VZ8_A 78.68 0 -
Thioesterase domain (100%) (view alignment) FASN (P49327) - 1XKT_B 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY0_A 87.07 0 COA K5L
Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%) (view alignment) FASN (P49327) - 6NNA_B 100 0 KUA CAF NDP
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (D0U2E3) - 4QYR_A 38.76 5.0E-77 -
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFD_A 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%) (view alignment) Fasn (P19096) - 5MY2_B 87.07 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksJ (P40806) - 4NA3_A 35.71 1.0E-68 2JG
Methyltransferase domain (100%), short chain dehydrogenase (100%) (view alignment) FASN (P49327) - 5C37_A 100 0 NDP 4XN
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_E 35.76 1.0E-69 -
Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%) (view alignment) FASN (P49327) - 4PIV_A 100 0 2W4 NDP
Methyltransferase domain (100%), short chain dehydrogenase (100%) (view alignment) FASN (P49327) - 5C37_C 100 0 NDP 4XN
Thioesterase domain (100%) (view alignment) FASN (P49327) - 1XKT_A 100 0 -
Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%) (view alignment) FASN (P49327) - 4PIV_B 100 0 2W4 NDP
Beta-ketoacyl synthase, N-terminal domain (99%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) pksL (Q05470) - 5ENY_D 35.76 1.0E-69 -
Zinc-binding dehydrogenase (100%) (view alignment) ppsC (P96202) - 4OKI_A 39.29 3.0E-31 -
Zinc-binding dehydrogenase (100%) (view alignment) FASN (P49327) - 4W9N_C 100 0 CCS
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%) (view alignment) (Q1RS72) - 5ERB_B 38.95 2.0E-76 -
Acyl transferase domain (100%) (view alignment) FASN (P49327) - 2JFD_C 100 0 -
Phosphopantetheine attachment site (100%) (view alignment) FASN (P49327) AASDHPPT (Q9NRN7) 2CG5_B 100 0 -
Beta-ketoacyl synthase, N-terminal domain (100%), Beta-ketoacyl synthase, C-terminal domain (100%), Acyl transferase domain (100%), Polyketide synthase dehydratase (100%), Methyltransferase domain (100%), Zinc-binding dehydrogenase (100%), short chain dehydrogenase (100%), Phosphopantetheine attachment site (100%), Thioesterase domain (100%) (view alignment) (A5YV76) - 2VZ8_B 78.68 0 -