MTNR1B (P49286) - Overview - Molecular Target Synopsis
MTNR1B, Melatonin receptor type 1B
Also Known as MTR1B_HUMAN, MTNR1B
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Interacts with GPR61, GPR62 and GPR135 (PubMed:28827538).
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: MTNR1B is active in the following subcellular-locations: cell membrane.
GO terms: MTNR1B is active in the following subcellular-locations: integral component of plasma membrane, plasma membrane.