TRPC1 (P48995) - Overview - Molecular Target Synopsis
TRPC1, Short transient receptor potential channel 1
Also Known as TRPC1_HUMAN, TRPC1, TRP1
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with TRPC4AP (By similarity). Homotetramer and heterotetramer with TRPC4 and/or TRPC5. Interacts with TRPC3, TRPC4 and TRPC5. Interacts with ITPR3. Interacts with MX1 and RNF24. Interacts with FKBP4.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: TRPC1 is active in the following subcellular-locations: membrane.
GO terms: TRPC1 is active in the following subcellular-locations: cation channel complex, integral component of plasma membrane, plasma membrane, receptor complex.