Molecular Target Synopsis
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rplGB (P46350) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/07/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 23/07/2019)


Chains assessed12
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria4


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
3V7E_B Ribosome-associated protein L7Ae-like Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.73 74.8 20.1 Yes No
2 empty 2.41 68.4 9.5 No No
3 empty 1.3 64.5 10.4 No No
4 empty 1.96 97.1 0 Yes No
5 empty 2.15 75.6 7.6 No No
6 empty 1.76 67.5 7 No No
7 empty 1.32 78.9 0 No No
8 empty 1.86 60 7.7 No No
4TZZ_D Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 59.8 8.4 No No
2 empty 1.91 63.7 9.4 No No
3 empty 1.4 72.6 8.5 No No
4 empty 1.41 59.3 8.7 No No
5 empty 1.9 55 7.1 No No
6 empty 1.42 63.8 5.9 No No
7 empty 1.46 58.8 6.5 No No
8 empty 1.35 72 4.8 No No
9 empty 2.44 68.5 8.3 No No
10 empty 2.77 67.9 6.1 No No
4TZV_A Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.22 60.1 11.8 No No
2 empty 2.36 64 7.2 No No
3 empty 1.45 74.4 6.6 No No
4 empty 2.52 65.9 6.7 No No
5 empty 1.77 76.2 6 No No
6 empty 1.71 72.6 5.8 No No
7 empty 2.63 61.5 5.9 No No
8 empty 2.31 60.5 4.4 No No
9 empty 2.78 68.6 5.5 No No
4TZZ_A Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.28 53.3 11.9 No No
2 empty 2.16 66.3 8.7 No No
3 empty 1.19 68.9 6.5 No No
4 empty 1.88 54.8 8.5 No No
5 empty 1.49 73.3 7.9 No No
6 empty 1.88 64.8 6.7 No No
7 empty 2.44 62 7 No No
8 empty 2.27 77.6 5.7 No No
9 empty 1.9 63.7 7.2 No No
10 empty 1.36 70.6 0 No No
4TZP_D Ribosome-associated protein L7Ae-like Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.62 75.3 8.5 Yes No
2 empty 1.45 64.8 9.3 No No
3 empty 2.4 70.3 8.3 No No
4 empty 2.18 63.4 8.1 No No
5 empty 2.34 53.5 8.9 No No
6 empty 2.52 64.1 5.5 No No
7 empty 2.16 62.6 6.4 No No
8 empty 2.18 83 6.6 No No
9 empty 1.8 67.9 6.1 No No
10 empty 2.99 64.4 0 No No
4TZZ_G Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.41 62.6 14 No No
2 empty 2.05 64.2 13.5 No No
3 empty 2.31 77.9 7.3 No No
4 empty 2.4 57.8 7.6 No No
5 empty 1.38 76.9 5.5 No No
6 empty 1.94 57.6 7.9 No No
7 empty 1.75 70 5.7 No No
8 empty 2.52 72.2 6 No No
9 empty 1.59 65.6 4.9 No No
4LCK_A Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.15 57.1 14.3 No No
2 empty 2.25 63.3 7 No No
3 empty 1.39 75 7.5 No No
4 empty 2.38 76.8 7 No No
5 empty 2.62 70.3 4.8 No No
6 empty 1.78 70.6 7 No No
7 empty 1.71 65.9 5.7 No No
8 empty 2.3 60.7 6.8 No No
4LCK_D Ribosome-associated protein L7Ae-like Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.55 60 12.4 No No
2 empty 1.08 73.5 8.6 Yes No
3 empty 2.35 70.7 10 No No
4 empty 1.61 56.7 16 No No
5 empty 2.43 70.7 10.7 No No
6 empty 2.32 62.5 10.9 No No
7 empty 2.45 67 5.7 No No
8 empty 2.2 87.3 0 Yes No
9 empty 2.02 53.2 5.6 No No
10 empty 2.1 65.4 4.3 No No
4TZP_A Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.33 61.2 9.6 No No
2 empty 1.14 59.9 8 No No
3 empty 1.37 73 7.7 No No
4 empty 2.5 73.2 6 No No
5 empty 2.5 71.6 5.4 No No
6 empty 1.87 72.7 6.3 No No
7 empty 2.19 62.9 7 No No
8 empty 1.38 72.4 6.1 No No
9 empty 2.82 60.9 5.1 No No
3V7E_A Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.35 57.5 11.7 No No
2 empty 2.36 63.4 9.2 No No
3 empty 2.43 68.9 7.3 No No
4 empty 2.07 74.4 0 No No
5 empty 1.32 69.2 6.5 No No
6 empty 2.26 67.7 6.5 No No
7 empty 1.51 60.2 5.4 No No
8 empty 2.66 60.2 5.7 No No
9 empty 2.24 61.4 5 No No
10 empty 2.16 59.8 6.4 No No
4TZW_A Ribosome-associated protein L7Ae-like Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.84 65.9 14.9 No No
2 empty 2.2 73.8 7.2 No No
3 empty 1.39 61.8 9 No No
4 empty 2.59 64.4 7.5 No No
5 empty 2.38 65.9 8.8 No No
6 empty 1.55 66.1 7 No No
7 empty 2 59.6 6.2 No No
8 empty 1.87 72.2 5.5 No No
9 empty 1.03 95.7 0 Yes No
10 empty 1.86 68.5 5.7 No No
4TZZ_J Ribosome-associated protein L7Ae-like No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.31 59.4 11.8 No No
2 empty 1.91 63.7 12.4 No No
3 empty 2.38 58.1 9.1 No No
4 empty 2.1 74.5 7.8 No No
5 empty 1.98 64.2 6.3 No No
6 empty 1.25 67 4.9 No No
7 empty 1.47 70.6 7.6 No No
8 empty 1.59 69.9 0 No No
9 empty 1.98 65.1 6.4 No No
10 empty 1.76 62.5 5.4 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score