Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rplGB (P46350) - Overview - Molecular Target Synopsis

Protein


rplGB, Ribosome-associated protein L7Ae-like
UniProt P46350

Also Known as RXL7_BACSU, rplGB, ybaB, ybxF

RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs. Found associated with the 50S subunit of the ribosome during exponential growth but not during stationary phase.

4TZP
AS GROWN, UNTREATED CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T- BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN
RCSB/PDB
Inspect Structure
See all 3D Structures for rplGB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
82P46350-1

Sub-cellular localization


UniProt: rplGB is active in the following subcellular-locations: cytoplasm.
GO terms: rplGB is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rplGB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rplGB there are:
6 structures (12 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis