Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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Germline Genetics

MAP2K4 (P45985) - Pathways - Molecular Target Synopsis

Data acquired from 40 pathway associations found
Pathway Name Source
FCERI mediated MAPK activationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1Reactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
MAP3K8 (TPL2)-dependent MAPK1/3 activationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Oxidative Stress Induced SenescenceReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Uptake and function of anthrax toxinsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
AngiogenesisPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Apoptosis signaling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
EGF receptor signaling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
FAS signaling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Fas signaling pathway ( Fas signaling pathway )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
FGF signaling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Gastrin_CCK2R_240212PANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Huntington diseasePANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
IL-1 signaling pathwaywikipathways
IL-6 signaling pathwaywikipathways
IL1NetPath 12/2011
IL6NetPath 12/2011
Integrin signalling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
JNK cascade ( EGF signaling pathway Diagram )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( IL-1 signaling pathway (through JNK cascade) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( PDGF signaling pathway )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( PDGF signaling pathway )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( TGF-beta signaling(through TAK1) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( TNFR1 signaling pathway )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( TNFR1 signaling pathway )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, JNK cascade) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
JNK cascade ( Toll-like receptor signaling pathway (through JNK cascade) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
Oxidative stress responsePANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
p38 cascade ( IL-1 signaling pathway (through p38 cascade) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
p38 cascade ( Toll-like receptor signaling pathway (p38 cascade) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
p38 cascade ( Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, p38 cascade) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
p38 MAPK pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
Ras PathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
TNFalphaNetPath 12/2011
VEGF signaling pathway ( VEGF signaling pathway )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
WntNetPath 12/2011