Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(P43529) - Overview - Molecular Target Synopsis

Protein


, Heat-labile enterotoxin IIB, B chain
UniProt P43529

Also Known as E2BB_ECOLX

The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. Heterohexamer of one A chain and of five B chains.

5G3L
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B- PENTAMER COMPLEXED WITH SIALYLATED SUGAR
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
122P43529-1

Sub-cellular localization


GO terms: is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
7 structures (55 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis