Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

Tnfsf4 (P43488) - Overview - Molecular Target Synopsis

Protein


Tnfsf4, Tumor necrosis factor ligand superfamily member 4
UniProt P43488

Also Known as TNFL4_MOUSE, Tnfsf4, Ox40l, Txgp1l

Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. Homotrimer.

2HEW
THE X-RAY CRYSTAL STRUCTURE OF MURINE OX40L
RCSB/PDB
Inspect Structure
See all 3D Structures for Tnfsf4

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
198P43488-1

Sub-cellular localization


UniProt: Tnfsf4 is active in the following subcellular-locations: membrane.
GO terms: Tnfsf4 is active in the following subcellular-locations: cell surface, extracellular space, integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project Tnfsf4 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For Tnfsf4 there are:
2 structures (3 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis