Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MSH2 (P43246) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH6 (P52701) HUMAN 2O8F_A 100 0 3.25Å ADP 2007-06-05
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH3 (P20585) HUMAN 3THW_A 100 0 3.09Å ADP 2011-12-21
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH3 (P20585) HUMAN 3THX_A 100 0 2.7Å ADP 2011-12-21
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH6 (P52701) HUMAN 2O8C_A 100 0 3.37Å ADP 2007-06-05
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH3 (P20585) HUMAN 3THY_A 100 0 2.89Å ADP 2011-12-21
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH6 (P52701) HUMAN 2O8E_A 100 0 3.3Å ADP 2007-06-05
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH6 (P52701) HUMAN 2O8B_A 100 0 2.75Å ADP 2007-06-05
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH3 (P20585) HUMAN 3THZ_A 100 0 4.3Å ADP 2011-12-21
MutS domain I (100%), MutS domain II (100%), MutS domain III (100%), MutS family domain IV (100%), MutS domain V (100%) (view alignment) MSH2 (P43246) MSH6 (P52701) HUMAN 2O8D_A 100 0 3Å ADP 2007-06-05