Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

GFP (P42212) - Overview - Molecular Target Synopsis

Protein


GFP, Green fluorescent protein
UniProt P42212

Also Known as GFP_AEQVI, GFP

Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin. Monomer.

6EFR
CRYSTAL STRUCTURE OF INICSNFR 1.0
RCSB/PDB
Inspect Structure
See all 3D Structures for GFP

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
238P42212-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project GFP has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

RNA Interference


GFP was reported in the following RNAI studies:

Cell - Large Scale Profiling of Kinase Dependencies in Cancer Cell Lines, the highest RNAi cell lines are: . (see details)

3D Structures


For GFP there are:
314 structures (495 chains) solved
299 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis