APOBEC1 (P41238) - Overview - Molecular Target Synopsis
APOBEC1, C->U-editing enzyme APOBEC-1
Enzyme Classification 220.127.116.11
Also Known as ABEC1_HUMAN, APOBEC1
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP.
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UniProt: APOBEC1 is active in the following subcellular-locations: cytoplasm.
GO terms: APOBEC1 is active in the following subcellular-locations: cytoplasm, nucleoplasm, nucleus.