Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pksJ (P40806) - Overview - Molecular Target Synopsis

Protein


pksJ, Polyketide synthase PksJ
UniProt P40806

Also Known as PKSJ_BACSU, pksJ, pksK

Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

5KTK
KETOREDUCTASE FROM MODULE 3 OF THE BACILLAENE SYNTHASE FROM BACILLUS SUBTILIS 168
RCSB/PDB
Inspect Structure
See all 3D Structures for pksJ

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
5043P40806-1

Sub-cellular localization


UniProt: pksJ is active in the following subcellular-locations: cytoplasm.
GO terms: pksJ is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project pksJ has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pksJ there are:
6 structures (9 chains) solved
4 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


pksJ has been screened with compounds ( bioactivities). (see details)