Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

argD (P40732) - Overview - Molecular Target Synopsis

Protein


argD, Acetylornithine/succinyldiaminopimelate aminotransferase
Enzyme Classification 2.6.1.11
UniProt P40732

Also Known as ARGD_SALTY, argD, dapC, dtu

Involved in both the arginine and lysine biosynthetic pathways. Homodimer.

4JEX
Y21K MUTANT OF N-ACETYLORNITHINE AMINOTRANSFERASE COMPLEXED WITH L- CANALINE
RCSB/PDB
Inspect Structure
See all 3D Structures for argD

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
405P40732-1

Sub-cellular localization


UniProt: argD is active in the following subcellular-locations: cytoplasm.
GO terms: argD is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project argD has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For argD there are:
9 structures (18 chains) solved
9 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


argD has been screened with compounds ( bioactivities). (see details)