Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ARL4A (P40617) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
ADP-ribosylation factor family (89%) (view alignment) Arl3 (Q9WUL7) RP2 (O75695) HOUSE MOUSE 3BH7_A 38.61 6.0E-26 1.9Å GDP 2008-03-25
ADP-ribosylation factor family (98%) (view alignment) (Q5AND9) - YEAST 5UF8_C 44.83 2.0E-40 1.87Å GDP 2017-01-25
ADP-ribosylation factor family (100%) (view alignment) ARF1 (P84077) - HUMAN 1HUR_B 42.7 5.0E-38 2Å GDP 1995-07-10
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5NZU_F 42.05 3.0E-37 15Å - 2017-06-28
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZT_M 42.05 3.0E-37 17Å - 2017-06-28
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) - HOUSE MOUSE 1FZQ_A 38.95 5.0E-27 1.7Å GDP MES 2000-12-06
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84080) IQSEC1 (Q6DN90) BOVINE 4C0A_C 45.18 7.0E-38 3.3Å G3D 2013-09-25
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) GOLGA4 (Q13439) HUMAN 1UPT_A 39.63 4.0E-29 1.7Å GTP 2003-10-30
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Arfgap2 (Q3MID3), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZS_R 42.05 3.0E-37 10.1Å - 2017-06-28
ADP-ribosylation factor family (93%) (view alignment) Arl2 (Q9D0J4) UNC119 (Q13432) MOUSE 4GOK_A 35.54 3.0E-24 2.6Å GNP 2012-09-19
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6D84_C 44.58 5.0E-37 6.72Å GTP 2018-08-08
ADP-ribosylation factor family (89%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_G 45.91 1.0E-37 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZV_R 42.05 3.0E-37 17.3Å - 2017-06-28
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), nef (P03404), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 6CRI_K 44.58 7.0E-37 6.8Å GTP 2018-08-01
ADP-ribosylation factor family (94%) (view alignment) Arf2 (Q8BSL7) GGA1 (Q9UJY5) HOUSE MOUSE 1J2J_A 44.91 2.0E-37 1.6Å GTP 2003-05-06
ADP-ribosylation factor family (94%) (view alignment) ARL2 (P36404) ARL2BP (Q9Y2Y0) HUMAN 3DOE_A 35.71 7.0E-25 2.25Å GTP 2009-03-03
ADP-ribosylation factor family (91%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H17_A 40.74 6.0E-31 1.7Å GDP 2006-06-13
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1Y_J 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC31 (P38968), SEC23 (P15303) BAKER'S YEAST 2QTV_B 39.69 1.0E-19 2.5Å GNP 2008-01-15
ADP-ribosylation factor family (98%) (view alignment) (C4LXL1) - 4YLG_B 43.43 3.0E-37 1.8Å GDP 2015-05-20
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) UNC119 (Q13432) MOUSE 4GOJ_B 38.95 5.0E-27 2.1Å GNP 2012-09-19
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84080) IQSEC1 (Q6DN90) BOVINE 4C0A_H 45.18 7.0E-38 3.3Å G3D 2013-09-25
ADP-ribosylation factor family (99%) (view alignment) ARF2 (P19146) - BAKER'S YEAST 1MR3_F 41.48 9.0E-37 1.6Å G3D 2002-11-20
ADP-ribosylation factor family (98%) (view alignment) (Q5AND9) - YEAST 5UF8_B 44.83 2.0E-40 1.87Å GDP 2017-01-25
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI2_B 38.95 5.0E-27 2.2Å GNP 2015-11-11
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Arfgap2 (Q3MID3), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZS_M 42.05 3.0E-37 10.1Å - 2017-06-28
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330), Cyth3 (O08967) - MOUSE, HUMAN 6BBP_A 44.38 3.0E-38 35Å GTP 4IP 2018-01-10
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5NZU_M 42.05 3.0E-37 15Å - 2017-06-28
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), nef (P03404), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 6CRI_V 44.58 7.0E-37 6.8Å GTP 2018-08-01
ADP-ribosylation factor family (98%) (view alignment) ARF1 (Q7KQL3) - 3LRP_A 41.95 3.0E-38 2.5Å GDP 2010-11-10
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84080) CYTH2 (Q99418) CATTLE 1R8S_A 45.18 7.0E-38 1.46Å GDP 2004-01-20
ADP-ribosylation factor family (75%) (view alignment) ARL8A (Q96BM9) - HUMAN 1ZD9_A 42.03 7.0E-23 1.7Å GDP 2005-05-17
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) GOLGA4 (Q13439) HUMAN 1UPT_C 39.63 4.0E-29 1.7Å GTP 2003-10-30
ADP-ribosylation factor family (89%) (view alignment) Arl3 (Q9WUL7) RP2 (O75695) HOUSE MOUSE 3BH6_A 37.97 5.0E-25 2.6Å GNP 2008-03-25
ADP-ribosylation factor family (95%) (view alignment) ARL1 (P38116) - BAKER'S YEAST 1MOZ_B 44.71 3.0E-34 3.17Å GDP 2002-10-09
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 4BZI_K 39.69 1.0E-19 23Å GNP 2013-09-18
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6DFF_C 44.58 5.0E-37 3.9Å GTP 2018-08-08
ADP-ribosylation factor family (94%) (view alignment) ARL2 (P36404) ARL2BP (Q9Y2Y0) HUMAN 3DOF_A 35.71 7.0E-25 3.3Å GTP 2009-03-03
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1V_R 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZV_P 42.05 3.0E-37 17.3Å - 2017-06-28
ADP-ribosylation factor family (94%) (view alignment) Arl2 (Q9D0J4) PDE6D (O43924) HOUSE MOUSE 1KSG_A 35.71 4.0E-25 2.3Å GTP 2002-05-08
ADP-ribosylation factor family (100%) (view alignment) Arf1 (P84079) - NORWAY RAT 1RRG_B 42.47 4.0E-38 2.4Å GDP 1996-06-20
ADP-ribosylation factor family (74%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FA9_A 35.11 5.0E-16 2.5Å GDP 2006-09-05
ADP-ribosylation factor family (89%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_C 45.91 1.0E-37 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P36397) - THALE-CRESS 3AQ4_A 43.75 2.0E-38 1.8Å GDP 2011-01-26
ADP-ribosylation factor family (94%) (view alignment) Arl2 (Q9D0J4) PDE6D (O43924) HOUSE MOUSE 1KSJ_A 35.71 4.0E-25 2.6Å GTP GDP 2002-05-08
ADP-ribosylation factor family (92%) (view alignment) ARF1 (P11076) COPG1 (P53620), COPZ1 (P35604) BAKER'S YEAST 3TJZ_A 43.29 7.0E-36 2.9Å GNP 2012-02-22
ADP-ribosylation factor family (74%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FMX_B 35.11 3.0E-16 1.8Å GDP 2006-09-05
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330) - HUMAN 2J5X_B 44.97 2.0E-39 2.8Å GSP 2006-09-21
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1V_J 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (74%) (view alignment) ARL8A (Q96BM9) - HUMAN 2H18_A 41.91 1.0E-22 1.9Å GDP 2006-06-13
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) GOLGA4 (Q13439) HUMAN 1UPT_E 39.63 4.0E-29 1.7Å GTP 2003-10-30
ADP-ribosylation factor family (92%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_C 42.68 6.0E-35 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (91%) (view alignment) ARF6 (P62330) RAB1A (P62820), (Q7DB50) HUMAN 4FME_F 46.3 1.0E-38 4.1Å GTP 2012-09-05
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1W_B 42.05 3.0E-37 18Å - 2015-07-08
ADP-ribosylation factor family (98%) (view alignment) (Q4QEJ1) - 2X77_B 39.56 2.0E-27 2.1Å GDP 2010-03-02
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) ARHGAP21 (Q5T5U3) MOUSE 2J59_B 44.91 2.0E-37 1.95Å GTP 2007-02-20
ADP-ribosylation factor family (93%) (view alignment) ARL6 (Q9H0F7) - HUMAN 2H57_C 36.69 9.0E-25 2Å GTP 2006-07-25
ADP-ribosylation factor family (93%) (view alignment) ARL6 (Q9H0F7) - HUMAN 2H57_A 36.69 9.0E-25 2Å GTP 2006-07-25
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330), ASAP3 (Q8TDY4) - HUMAN 3LVR_E 45.14 5.0E-39 3.38Å GDP 2010-06-09
ADP-ribosylation factor family (89%) (view alignment) ARF6 (P62330) SPAG9 (O60271) HUMAN 2W83_A 45.91 1.0E-37 1.93Å GTP 2009-07-14
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_C 40.85 2.0E-31 2Å GDP 2006-06-13
ADP-ribosylation factor family (100%) (view alignment) Arf1 (P84079) - NORWAY RAT 1RRG_A 42.47 4.0E-38 2.4Å GDP 1996-06-20
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) ARHGAP21 (Q5T5U3) MOUSE 2J59_E 44.91 2.0E-37 1.95Å GTP 2007-02-20
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) ARFIP2 (P53365) HUMAN 4DCN_B 39.63 4.0E-29 3Å GNP 2012-06-13
ADP-ribosylation factor family (95%) (view alignment) ARF1 (P84077) IQSEC2 (Q5JU85) HUMAN 6FAE_B 46.15 1.0E-39 2.35Å - 2018-01-17
ADP-ribosylation factor family (93%) (view alignment) ARL5A (Q9Y689) - HUMAN 1Z6Y_B 40.36 3.0E-31 2.4Å GDP 2005-04-05
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZV_T 42.05 3.0E-37 17.3Å - 2017-06-28
ADP-ribosylation factor family (77%) (view alignment) ARL13 (A8INQ0) - 4M9Q_C 35.77 4.0E-16 2.5Å GNP 2013-11-06
ADP-ribosylation factor family (74%) (view alignment) ARL8A (Q96BM9) - HUMAN 4ILE_A 41.91 2.0E-22 2.676Å GDP 2014-01-01
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1X_A 42.05 3.0E-37 23Å - 2015-07-08
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) UNC119 (Q13432) MOUSE 4GOJ_A 38.95 5.0E-27 2.1Å GNP 2012-09-19
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI3_A 38.95 5.0E-27 2Å GNP 2016-03-23
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6D84_H 44.58 5.0E-37 6.72Å GTP 2018-08-08
ADP-ribosylation factor family (98%) (view alignment) (C4LXL1) - 4Y0V_A 43.43 3.0E-37 1.8Å GDP 2015-03-04
ADP-ribosylation factor family (74%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FMX_A 35.11 3.0E-16 1.8Å GDP 2006-09-05
ADP-ribosylation factor family (92%) (view alignment) Arl1 (P61212) GOLGA4 (Q13439) NORWAY RAT 1R4A_D 40.24 4.0E-30 2.1Å GNP 2004-01-13
ADP-ribosylation factor family (92%) (view alignment) Arl1 (P61212) GOLGA4 (Q13439) NORWAY RAT 1R4A_B 40.24 4.0E-30 2.1Å GNP 2004-01-13
ADP-ribosylation factor family (98%) (view alignment) (Q5AND9) - YEAST 5UF8_D 44.83 2.0E-40 1.87Å GDP 2017-01-25
ADP-ribosylation factor family (98%) (view alignment) (C4LXL1) - 4Y0V_B 43.43 3.0E-37 1.8Å GDP 2015-03-04
ADP-ribosylation factor family (77%) (view alignment) ARL13 (A8INQ0) - 4M9Q_A 35.77 4.0E-16 2.5Å GNP 2013-11-06
ADP-ribosylation factor family (93%) (view alignment) Arl2 (Q9D0J4) UNC119 (Q13432) MOUSE 4GOK_B 35.54 3.0E-24 2.6Å GNP 2012-09-19
ADP-ribosylation factor family (74%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 1F6B_B 35.11 4.0E-16 1.7Å GDP 2002-01-09
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1U_A 42.05 3.0E-37 13Å - 2015-07-08
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) ARFGEF1 (Q9Y6D6) HUMAN 5EE5_B 39.63 4.0E-29 2.279Å GTP 2016-07-06
ADP-ribosylation factor family (95%) (view alignment) ARL1 (P38116) - BAKER'S YEAST 1MOZ_A 44.71 3.0E-34 3.17Å GDP 2002-10-09
ADP-ribosylation factor family (94%) (view alignment) ARFGAP1 (Q8N6T3), ARF1 (P84077) - HUMAN 3O47_B 44.64 2.0E-37 2.8Å GDP 2010-08-11
ADP-ribosylation factor family (94%) (view alignment) Arl2 (Q9D0J4) PDE6D (O43924) HOUSE MOUSE 1KSH_A 35.71 4.0E-25 1.8Å GDP 2002-05-08
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 4BZI_B 39.69 1.0E-19 23Å GNP 2013-09-18
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330), ASAP3 (Q8TDY4) - HUMAN 3LVQ_E 45.14 5.0E-39 3.38Å GDP 2010-06-09
ADP-ribosylation factor family (100%) (view alignment) ARF1 (P84080) CYTH2 (Q99418) CATTLE 1R8Q_B 42.47 4.0E-38 1.86Å G3D AFB 2004-01-20
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) GEA1 (P47102) HUMAN 1RE0_A 45.18 7.0E-38 2.4Å GDP AFB 2003-12-16
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6D83_H 44.58 5.0E-37 4.27Å GTP 2018-08-08
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6CM9_H 44.58 5.0E-37 3.73Å GTP 2018-08-08
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZT_J 42.05 3.0E-37 17Å - 2017-06-28
ADP-ribosylation factor family (92%) (view alignment) ARF1 (P11076) COPG1 (P53620), COPZ1 (P35604) BAKER'S YEAST 3TJZ_D 43.29 7.0E-36 2.9Å GNP 2012-02-22
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), nef (P03404), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 6CRI_C 44.58 7.0E-37 6.8Å GTP 2018-08-01
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), nef (P03404), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 6CRI_U 44.58 7.0E-37 6.8Å GTP 2018-08-01
ADP-ribosylation factor family (100%) (view alignment) ARF1 (P11076) - YEAST 2KSQ_A 40.45 1.0E-34 GTP MTN 2010-07-07
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 6GNI_B 39.69 1.0E-19 4.9Å GNP 2018-10-17
ADP-ribosylation factor family (89%) (view alignment) ARF6 (P62330) SPAG9 (O60271) HUMAN 2W83_B 45.91 1.0E-37 1.93Å GTP 2009-07-14
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) ARFGEF1 (Q9Y6D6) HUMAN 5J5C_A 39.63 4.0E-29 3.4Å GTP 2016-09-28
ADP-ribosylation factor family (89%) (view alignment) ARL3 (A8ISN6) ARL13 (A8INQ0) 5DI3_A 38.36 4.0E-29 2.5Å GNP 2015-11-18
ADP-ribosylation factor family (89%) (view alignment) ARF6 (P62330) SPAG9 (O60271) HUMAN 2W83_E 45.91 1.0E-37 1.93Å GTP 2009-07-14
ADP-ribosylation factor family (91%) (view alignment) ARF6 (P62330) RAB1A (P62820), (Q7DB50) HUMAN 4FME_C 46.3 1.0E-38 4.1Å GTP 2012-09-05
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI2_A 38.95 5.0E-27 2.2Å GNP 2015-11-11
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1X_J 42.05 3.0E-37 23Å - 2015-07-08
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330) ctxA (P01555) HUMAN 2A5F_A 44.97 2.0E-39 2.02Å GTP 2005-08-16
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6D83_C 44.58 5.0E-37 4.27Å GTP 2018-08-08
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1Y_R 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5NZU_R 42.05 3.0E-37 15Å - 2017-06-28
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC23 (P15303) BAKER'S YEAST 1M2O_B 39.69 1.0E-19 2.5Å GNP 2002-09-20
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84080) IQSEC1 (Q6DN90) BOVINE 4C0A_G 45.18 7.0E-38 3.3Å G3D 2013-09-25
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZV_M 42.05 3.0E-37 17.3Å - 2017-06-28
ADP-ribosylation factor family (92%) (view alignment) ARF6 (P62330) CYTH3 (O43739) HUMAN 4KAX_A 46.01 4.0E-38 1.85Å GTP 2013-08-14
ADP-ribosylation factor family (99%) (view alignment) ARF4 (P18085) - HUMAN 1Z6X_A 44.32 3.0E-39 2.7Å GDP 2005-04-12
ADP-ribosylation factor family (92%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_L 42.68 6.0E-35 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (98%) (view alignment) (C4LXL1) - 4YLG_A 43.43 3.0E-37 1.8Å GDP 2015-05-20
ADP-ribosylation factor family (100%) (view alignment) ARF1 (P84080) CYTH2 (Q99418) CATTLE 1R8Q_A 42.47 4.0E-38 1.86Å G3D AFB 2004-01-20
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) - HUMAN 1U81_A 45.18 7.0E-38 GDP 2004-10-05
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1V_B 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (92%) (view alignment) Arl1 (P61212) GOLGA4 (Q13439) NORWAY RAT 1R4A_A 40.24 4.0E-30 2.1Å GNP 2004-01-13
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5NZR_M 42.05 3.0E-37 9.2Å - 2017-06-28
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) - HOUSE MOUSE 1O3Y_B 44.91 2.0E-37 1.5Å GTP 2003-05-20
ADP-ribosylation factor family (95%) (view alignment) ARL5B (Q96KC2) - HUMAN 1YZG_A 43.2 5.0E-34 2Å GDP 2005-03-22
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330) ctxA (P01555) HUMAN 2A5D_A 44.97 2.0E-39 1.8Å GTP 2005-08-16
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZT_R 42.05 3.0E-37 17Å - 2017-06-28
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_A 40.85 2.0E-31 2Å GDP 2006-06-13
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) ARFIP2 (P53365) HUMAN 4DCN_A 39.63 4.0E-29 3Å GNP 2012-06-13
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6D84_N 44.58 5.0E-37 6.72Å GTP 2018-08-08
ADP-ribosylation factor family (92%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_F 42.68 6.0E-35 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (100%) (view alignment) ARF1 (P84077) - HUMAN 1HUR_A 42.7 5.0E-38 2Å GDP 1995-07-10
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_D 40.85 2.0E-31 2Å GDP 2006-06-13
ADP-ribosylation factor family (94%) (view alignment) ARFGAP1 (Q8N6T3), ARF1 (P84077) - HUMAN 3O47_A 44.64 2.0E-37 2.8Å GDP 2010-08-11
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), nef (P03404), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 6CRI_H 44.58 7.0E-37 6.8Å GTP 2018-08-01
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZV_F 42.05 3.0E-37 17.3Å - 2017-06-28
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84080) IQSEC1 (Q6DN90) BOVINE 4C0A_D 45.18 7.0E-38 3.3Å G3D 2013-09-25
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1X_B 42.05 3.0E-37 23Å - 2015-07-08
ADP-ribosylation factor family (89%) (view alignment) ARF6 (P62330) - HUMAN 3N5C_A 46.54 1.0E-38 1.82Å GDP 2010-08-18
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), nef (P03404), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 6CRI_L 44.58 7.0E-37 6.8Å GTP 2018-08-01
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1V_S 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (89%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_A 45.91 1.0E-37 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (93%) (view alignment) ARL5A (Q9Y689) - HUMAN 1ZJ6_A 40.36 3.0E-31 2Å G3D 2005-06-07
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1W_A 42.05 3.0E-37 18Å - 2015-07-08
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6DFF_H 44.58 5.0E-37 3.9Å GTP 2018-08-08
ADP-ribosylation factor family (92%) (view alignment) Arl1 (P61212) GOLGA4 (Q13439) NORWAY RAT 1R4A_C 40.24 4.0E-30 2.1Å GNP 2004-01-13
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) ARHGAP21 (Q5T5U3) MOUSE 2J59_F 44.91 2.0E-37 1.95Å GTP 2007-02-20
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1U_B 42.05 3.0E-37 13Å - 2015-07-08
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_B 40.85 2.0E-31 2Å GDP 2006-06-13
ADP-ribosylation factor family (75%) (view alignment) ARL8B (Q9NVJ2) - HUMAN 2AL7_A 39.86 3.0E-22 1.85Å GDP 2005-08-23
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1Y_A 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (93%) (view alignment) ARL5A (Q9Y689) - HUMAN 1Z6Y_A 40.36 3.0E-31 2.4Å GDP 2005-04-05
ADP-ribosylation factor family (100%) (view alignment) Arf1 (P84079) - NORWAY RAT 1RRF_A 42.47 4.0E-38 3Å GDP 1996-06-20
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1Y_I 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (77%) (view alignment) ARL13 (A8INQ0) - 4M9Q_B 35.77 4.0E-16 2.5Å GNP 2013-11-06
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1V_I 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5NZR_F 42.05 3.0E-37 9.2Å - 2017-06-28
ADP-ribosylation factor family (93%) (view alignment) ARL6 (Q9H0F7) - HUMAN 2H57_B 36.69 9.0E-25 2Å GTP 2006-07-25
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC23 (P15303) BAKER'S YEAST 1M2O_D 39.69 1.0E-19 2.5Å GNP 2002-09-20
ADP-ribosylation factor family (74%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FA9_B 35.11 5.0E-16 2.5Å GDP 2006-09-05
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) ARHGAP21 (Q5T5U3) MOUSE 2J59_D 44.91 2.0E-37 1.95Å GTP 2007-02-20
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6CM9_C 44.58 5.0E-37 3.73Å GTP 2018-08-08
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P36397) - THALE-CRESS 3AQ4_B 43.75 2.0E-38 1.8Å GDP 2011-01-26
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Arfgap2 (Q3MID3), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZS_F 42.05 3.0E-37 10.1Å - 2017-06-28
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330) - HUMAN 1E0S_A 44.97 2.0E-39 2.28Å GDP 2000-04-18
ADP-ribosylation factor family (95%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI3_B 38.95 5.0E-27 2Å GNP 2016-03-23
ADP-ribosylation factor family (92%) (view alignment) ARL1 (P40616) GOLGA4 (Q13439) HUMAN 1UPT_G 39.63 4.0E-29 1.7Å GTP 2003-10-30
ADP-ribosylation factor family (74%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 4BZI_J 39.69 1.0E-19 23Å GNP 2013-09-18
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) ARHGAP21 (Q5T5U3) MOUSE 2J59_A 44.91 2.0E-37 1.95Å GTP 2007-02-20
ADP-ribosylation factor family (98%) (view alignment) (Q5AND9) - YEAST 5UF8_A 44.83 2.0E-40 1.87Å GDP 2017-01-25
ADP-ribosylation factor family (92%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_I 42.68 6.0E-35 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (98%) (view alignment) (Q4QEJ1) - 2X77_A 39.56 2.0E-27 2.1Å GDP 2010-03-02
ADP-ribosylation factor family (98%) (view alignment) ARF5 (P84085) - HUMAN 2B6H_A 43.58 2.0E-38 1.76Å GDP 2005-10-11
ADP-ribosylation factor family (89%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_E 45.91 1.0E-37 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330), Cyth3 (O08967) - MOUSE, HUMAN 6BBQ_A 44.38 3.0E-38 35Å GTP 4IP 2018-01-10
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330) ctxA (P01555) HUMAN 2A5G_A 44.38 2.0E-38 2.66Å GTP 2005-08-16
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5NZT_F 42.05 3.0E-37 17Å - 2017-06-28
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5NZR_R 42.05 3.0E-37 9.2Å - 2017-06-28
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) - RAT 2K5U_A 42.05 3.0E-37 GDP 2009-01-27
ADP-ribosylation factor family (89%) (view alignment) ARF6 (P62330) - HUMAN 3N5C_B 46.54 1.0E-38 1.82Å GDP 2010-08-18
ADP-ribosylation factor family (95%) (view alignment) ARF6 (P62330) - HUMAN 2J5X_A 44.97 2.0E-39 2.8Å GSP 2006-09-21
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copg1 (Q9QZE5), Copz1 (P61924), Copa (Q8CIE6), Copb2 (O55029), Arcn1 (Q5XJY5), Copb1 (Q9JIF7) BAKER'S YEAST 5A1X_I 42.05 3.0E-37 23Å - 2015-07-08
ADP-ribosylation factor family (89%) (view alignment) ARL3 (A8ISN6) - 5DE3_A 38.36 3.0E-29 1.4Å GNP 2016-09-14
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1Y_B 42.05 3.0E-37 21Å - 2015-07-08
ADP-ribosylation factor family (89%) (view alignment) ARF6 (P62330) (Q7DB50) HUMAN 3PCR_B 46.54 1.0E-38 2.5Å GTP 2011-01-05
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) - HOUSE MOUSE 1O3Y_A 44.91 2.0E-37 1.5Å GTP 2003-05-20
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84080) CYTH2 (Q99418) CATTLE 1S9D_A 45.18 7.0E-38 1.8Å GDP AFB 2004-02-10
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), Ap1m1 (P35585), AP1S3 (Q96PC3), AP1B1 (Q10567) HUMAN 4HMY_C 44.58 6.0E-37 7Å GTP 2013-03-06
ADP-ribosylation factor family (99%) (view alignment) ARF4 (P18085) - HUMAN 1Z6X_B 44.32 3.0E-39 2.7Å GDP 2005-04-12
ADP-ribosylation factor family (74%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 1F6B_A 35.11 4.0E-16 1.7Å GDP 2002-01-09
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P84077) Ap1g1 (P22892), BST2 (Q10589), Ap1m1 (P35585), AP1S3 (Q96PC3), (Q90VU7), AP1B1 (Q10567) HUMAN 6D84_I 44.58 5.0E-37 6.72Å GTP 2018-08-08
ADP-ribosylation factor family (77%) (view alignment) ARL13 (A8INQ0) ARL3 (A8ISN6) 5DI3_B 35.77 3.0E-16 2.5Å GNP 2015-11-18
ADP-ribosylation factor family (94%) (view alignment) Arf1 (P84078) ARHGAP21 (Q5T5U3) MOUSE 2J59_C 44.91 2.0E-37 1.95Å GTP 2007-02-20
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) Copb1 (Q9JIF7), Cope (O89079), Copz1 (P61924), Copg1 (Q9QZE5), Copb2 (O55029), Copa (Q8CIE6), Arcn1 (Q5XJY5) BAKER'S YEAST 5A1V_A 42.05 3.0E-37 21Å - 2015-07-08