ARL4A (P40617) - Overview - Molecular Target Synopsis
ARL4A, ADP-ribosylation factor-like protein 4A
Also Known as ARL4A_HUMAN, ARL4A, ARL4
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. Interacts with CYTH2. Interacts with KPNA2; the interaction is direct. Does not interacts with ARL4A.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: ARL4A is active in the following subcellular-locations: cell membrane, cytoplasm, nucleolus, nucleus.
GO terms: ARL4A is active in the following subcellular-locations: cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, plasma membrane.