Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

nirK (P38501) - Overview - Molecular Target Synopsis

Protein


nirK, Copper-containing nitrite reductase
Enzyme Classification 1.7.2.1
UniProt P38501

Also Known as NIR_ALCFA, nirK, nir

Homotrimer.

5F7B
RESTING STATE STRUCTURE OF CUNIR FORM ALCALIGENES FAECALIS DETERMINED AT 293 K
RCSB/PDB
Inspect Structure
See all 3D Structures for nirK

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
376P38501-1

Sub-cellular localization


UniProt: nirK is active in the following subcellular-locations: periplasm.
GO terms: nirK is active in the following subcellular-locations: periplasmic space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project nirK has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For nirK there are:
47 structures (131 chains) solved
12 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis