Molecular Target Synopsis
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Domains and Structures
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Ligand Efficiency Plot
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MED8 (P38304) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) RPB11 (P38902), SRB5 (P32585), RPB5 (P20434), TOA1 (P32773), RPO21 (P04050), RPO26 (P20435), MED4 (Q12343), SRB6 (P32570), SSL2 (Q00578), RAD3 (P06839), RPC10 (P40422), TAF14 (P35189), SRB7 (P47822), CSE2 (P33308), MED7 (Q08278), TFG1 (P41895), TFG2 (P41896), SRB4 (P32569), MED11 (Q99278), SUA7 (P29055), RPB8 (P20436), TFA1 (P36100), RPB2 (P08518), RPB3 (P16370), SPT15 (P13393), SRB2 (P34162), TOA2 (P32774), TFB5 (Q3E7C1), RPB4 (P20433), MED6 (P38782), RPB10 (P22139), TFA2 (P36145), TFB2 (Q02939), RPB9 (P27999), SOH1 (P38633), RPB7 (P34087) BAKER'S YEAST 5SVA_N 100 0 15.3Å - 2016-09-28
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585), SRB6 (P32570), SRB4 (P32569), MED11 (Q99278), MED6 (P38782) BREWER'S YEAST,LAGER BEER YEAST,YEAST 3RJ1_J 100 0 4.3Å - 2011-07-27
Mediator of RNA polymerase II transcription complex subunit 8 (12%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585) BAKER'S YEAST 2HZS_I 100 0 2.7Å - 2006-09-12
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585), SRB6 (P32570), SRB4 (P32569), MED11 (Q99278), MED6 (P38782) BREWER'S YEAST,LAGER BEER YEAST,YEAST 3RJ1_Q 100 0 4.3Å - 2011-07-27
Mediator of RNA polymerase II transcription complex subunit 8 (12%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585) BAKER'S YEAST 2HZS_L 100 0 2.7Å - 2006-09-12
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585), SRB6 (P32570), SRB4 (P32569), MED11 (Q99278), MED6 (P38782) BREWER'S YEAST,LAGER BEER YEAST,YEAST 3RJ1_C 100 0 4.3Å - 2011-07-27
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) RPB11 (P38902), SRB5 (P32585), RPB8 (P20436), RPB5 (P20434), RPB2 (P08518), RPO21 (P04050), RPB3 (P16370), SRB2 (P34162), SPT15 (P13393), RPO26 (P20435), SRB6 (P32570), MED6 (P38782), (A0A0H2UKZ8), RPB4 (P20433), RPB10 (P22139), RPC10 (P40422), TFG2 (P41896), RPB9 (P27999), SRB4 (P32569), RPB7 (P34087), MED11 (Q99278), SUA7 (P29055) BAKER'S YEAST 4V1O_U 100 0 9.7Å - 2015-02-04
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585), SRB6 (P32570), SRB4 (P32569), MED11 (Q99278), MED6 (P38782) BAKER'S YEAST 4GWP_C 100 0 4.2Å - 2012-10-31
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) SRB5 (P32585), RPO21 (P04050), SRB2 (P34162), SRB4 (P32569), SRB6 (P32570), MED6 (P38782), MED11 (Q99278) BAKER'S YEAST 4GWQ_C 100 0 4.5Å - 2012-10-31
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585), SRB6 (P32570), SRB4 (P32569), MED11 (Q99278), MED6 (P38782) YEAST 3J1O_J 100 0 16Å - 2013-03-06
Mediator of RNA polymerase II transcription complex subunit 8 (100%) (view alignment) MED8 (P38304) RPB11 (P38902), SRB5 (P32585), TFB1 (P32776), RPB5 (P20434), TOA1 (P32773), RPO21 (P04050), ROX3 (P25046), RPO26 (P20435), MED4 (Q12343), SRB6 (P32570), SSL2 (Q00578), RAD3 (P06839), TFB3 (Q03290), RPC10 (P40422), SRB7 (P47822), CSE2 (P33308), MED7 (Q08278), TFG1 (P41895), TFG2 (P41896), SRB4 (P32569), MED11 (Q99278), SUA7 (P29055), RPB8 (P20436), TFA1 (P36100), RPB2 (P08518), RPB3 (P16370), SPT15 (P13393), SRB2 (P34162), TOA2 (P32774), TFB5 (Q3E7C1), RPB4 (P20433), MED6 (P38782), RPB10 (P22139), SSL1 (Q04673), RGR1 (P19263), TFA2 (P36145), TFB2 (Q02939), RPB9 (P27999), SOH1 (P38633), TFB4 (Q12004), RPB7 (P34087), NUT2 (Q06213) BAKER'S YEAST 5OQM_b 100 0 5.8Å - 2018-05-09
Mediator of RNA polymerase II transcription complex subunit 8 (12%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585) BAKER'S YEAST 2HZS_J 100 0 2.7Å - 2006-09-12
Mediator of RNA polymerase II transcription complex subunit 8 (12%) (view alignment) MED8 (P38304) SRB2 (P34162), SRB5 (P32585) BAKER'S YEAST 2HZS_K 100 0 2.7Å - 2006-09-12