Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLM4 (P38247) - Overview - Molecular Target Synopsis

Protein


SLM4, Protein SLM4
UniProt P38247

Also Known as SLM4_YEAST, SLM4, EGO3, GSE1

Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy. Component of the GSE complex composed of GTR1, GTR2, SLM4, MEH1 and LTV1. Component of the EGO complex, at least composed of GTR2, SLM4 and MEH1.

4XPM
CRYSTAL STRUCTURE OF EGO-TC
RCSB/PDB
Inspect Structure
See all 3D Structures for SLM4

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
162P38247-1

Sub-cellular localization


UniProt: SLM4 is active in the following subcellular-locations: vacuole membrane.
GO terms: SLM4 is active in the following subcellular-locations: cytoplasm, EGO complex, fungal-type vacuole membrane, integral component of membrane, late endosome membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLM4 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For SLM4 there are:
4 structures (6 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis