Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

estA (P37957) - Overview - Molecular Target Synopsis

Protein


estA, Lipase EstA
Enzyme Classification 3.1.1.3
UniProt P37957

Also Known as ESTA_BACSU, estA, lip, lipA

Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups.

5CTA
G158E/K44E/R57E/Y49E BACILLUS SUBTILIS LIPASE A WITH 10% [BMIM][CL]
RCSB/PDB
Inspect Structure
See all 3D Structures for estA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
212P37957-1

Sub-cellular localization


UniProt: estA is active in the following subcellular-locations: secreted.
GO terms: estA is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project estA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For estA there are:
21 structures (50 chains) solved
8 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis