Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rluB (P37765) - Overview - Molecular Target Synopsis

Protein


rluB, Ribosomal large subunit pseudouridine synthase B
Enzyme Classification 5.4.99.22
UniProt P37765

Also Known as RLUB_ECOLI, rluB, yciL

Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.

4LAB
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF RLUB
RCSB/PDB
Inspect Structure
See all 3D Structures for rluB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
291P37765-1

Sub-cellular localization


GO terms: rluB is active in the following subcellular-locations: cytosol.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rluB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rluB there are:
2 structures (3 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis