Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ppaC (P37487) - Overview - Molecular Target Synopsis

Protein


ppaC, Manganese-dependent inorganic pyrophosphatase
Enzyme Classification 3.6.1.1
UniProt P37487

Also Known as PPAC_BACSU, ppaC

Homodimer.

2HAW
CRYSTAL STRUCTURE OF FAMILY II INORGANIC PYROPHOSPHATASE IN COMPLEX WITH PNP
RCSB/PDB
Inspect Structure
See all 3D Structures for ppaC

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
309P37487-1

Sub-cellular localization


UniProt: ppaC is active in the following subcellular-locations: cytoplasm.
GO terms: ppaC is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ppaC has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For ppaC there are:
5 structures (12 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis