Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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cueO (P36649) - Overview - Molecular Target Synopsis

Protein


cueO, Blue copper oxidase CueO
UniProt P36649

Also Known as CUEO_ECOLI, cueO, yacK

Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm. Monomer.

6IM7
CUEO-12.1 MULTICOPPER OXIDASE
RCSB/PDB
Inspect Structure
See all 3D Structures for cueO

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
516P36649-1

Sub-cellular localization


UniProt: cueO is active in the following subcellular-locations: periplasm.
GO terms: cueO is active in the following subcellular-locations: outer membrane-bounded periplasmic space, periplasmic space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project cueO has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For cueO there are:
39 structures (43 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis