Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

BYE1 (P36106) - Overview - Molecular Target Synopsis

Protein


BYE1, Transcription factor BYE1
UniProt P36106

Also Known as BYE1_YEAST, BYE1

Negative regulator of transcription elongation. Interacts with the RNA polymerase RPB1 subunit and specifically with the trimethylated H3 histone H3K4me3.

4BXX
ARRESTED RNA POLYMERASE II-BYE1 COMPLEX
RCSB/PDB
Inspect Structure
See all 3D Structures for BYE1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
594P36106-1

Sub-cellular localization


UniProt: BYE1 is active in the following subcellular-locations: nucleus.
GO terms: BYE1 is active in the following subcellular-locations: nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project BYE1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For BYE1 there are:
4 structures (4 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis