Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

OAR1 (P35731) - Overview - Molecular Target Synopsis

Protein


OAR1, 3-oxoacyl-[acyl-carrier-protein] reductase
Enzyme Classification 1.1.1.100
UniProt P35731

Also Known as FABG_YEAST, OAR1

Involved in biosynthesis of fatty acids in mitochondria.

4HBG
CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE 3 OXOACYL-[ACYL CARRIER PROTEIN]-REDUCTASE COMPLEXED WITH NADPH (FORM2)
RCSB/PDB
Inspect Structure
See all 3D Structures for OAR1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
278P35731-1

Sub-cellular localization


UniProt: OAR1 is active in the following subcellular-locations: mitochondrion.
GO terms: OAR1 is active in the following subcellular-locations: mitochondrion.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project OAR1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For OAR1 there are:
3 structures (8 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis