Molecular Target Synopsis
Overview
Domains and Structures
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Chemistry
Ligand Efficiency Plot
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Gene Expression
Gene Copy Number Variation
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resA (P35160) - Overview - Molecular Target Synopsis

Protein


resA, Thiol-disulfide oxidoreductase ResA
UniProt P35160

Also Known as RESA_BACSU, resA, ypxA

Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation.

3C73
STRUCTURE OF CEHC VARIANT RESA
RCSB/PDB
Inspect Structure
See all 3D Structures for resA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
179P35160-1

Sub-cellular localization


UniProt: resA is active in the following subcellular-locations: cell membrane.
GO terms: resA is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project resA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For resA there are:
10 structures (21 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis