Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RPC82 (P32349) - Overview - Molecular Target Synopsis

Protein


RPC82, DNA-directed RNA polymerase III subunit RPC3
UniProt P32349

Also Known as RPC3_YEAST, RPC82, RPC3

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.

6CNF
YEAST RNA POLYMERASE III ELONGATION COMPLEX
RCSB/PDB
Inspect Structure
See all 3D Structures for RPC82

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
654P32349-1

Sub-cellular localization


UniProt: RPC82 is active in the following subcellular-locations: cytoplasm, nucleus.
GO terms: RPC82 is active in the following subcellular-locations: cytoplasm, nucleoplasm, RNA polymerase III complex.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project RPC82 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For RPC82 there are:
15 structures (15 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis