Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

HOXD11 (P31277) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Homeodomain (100%) (view alignment) Abd-B (P09087) exd (P40427) FRUIT FLY 5ZJQ_A 68.42 5.0E-17 2.44Å - 2018-08-29
Homeodomain (99%) (view alignment) CDX2 (Q99626) - HUMAN 6ES2_L 50 1.0E-11 2.95Å - 2018-03-21
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EDN_J 56.92 5.0E-15 3.2Å - 2016-11-09
Homeodomain (100%) (view alignment) PDX1 (P70118) - GOLDEN HAMSTER 2H1K_A 56.9 5.0E-14 2.42Å - 2007-03-20
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 5JLW_A 54.24 7.0E-13 2.088Å - 2016-06-22
Homeodomain (95%) (view alignment) HOXB1 (P14653) PBX1 (P40424) HUMAN 1B72_A 50 8.0E-12 2.35Å - 1999-02-19
Homeodomain (100%) (view alignment) Ubx (P83949) exd (P40427) FRUIT FLY 1B8I_A 54.39 7.0E-13 2.4Å - 1999-04-12
Homeodomain (99%) (view alignment) CDX2 (Q99626) - HUMAN 6ES2_K 50 1.0E-11 2.95Å - 2018-03-21
Homeodomain (100%) (view alignment) HOXB13 (Q92826) MEIS2 (O14770) HUMAN 5EG0_B 58.62 7.0E-14 2.97Å - 2016-11-09
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 4XID_D 54.24 7.0E-13 2.7Å - 2015-11-25
Homeodomain (100%) (view alignment) Ubx (P83949) - FRUIT FLY 4UUT_A 54.39 1.0E-12 2.8Å - 2015-02-18
Homeodomain (100%) (view alignment) Scr (P09077) exd (P40427) FRUIT FLY 2R5Z_A 49.25 7.0E-14 2.6Å - 2008-02-05
Homeodomain (100%) (view alignment) Hoxa9 (P09631) PBX1 (P40424) HOUSE MOUSE 1PUF_A 58.33 2.0E-21 1.9Å - 2003-09-02
Homeodomain (100%) (view alignment) HOXB13 (Q92826) TEAD4 (Q15561) HUMAN 5NO6_A 58.62 6.0E-13 2.88Å - 2018-05-16
Homeodomain (99%) (view alignment) CDX1 (P47902) - HUMAN 5LUX_K 52.54 7.0E-11 3.23Å - 2017-05-17
Homeodomain (100%) (view alignment) Abd-B (P09087) exd (P40427) FRUIT FLY 5ZJT_E 68.42 5.0E-17 2.4Å - 2018-08-29
Homeodomain (100%) (view alignment) Abd-B (P09087) exd (P40427) FRUIT FLY 5ZJS_A 68.42 5.0E-17 2.896Å - 2018-08-29
Homeodomain (100%) (view alignment) HOXA13 (P31271) - HUMAN 2L7Z_A 62.07 1.0E-14 - 2011-11-09
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 2CRA_A 59.65 8.0E-15 - 2005-11-20
Homeodomain (100%) (view alignment) Ubx (P83949) exd (P40427) FRUIT FLY 4CYC_A 54.39 1.0E-12 2.36Å - 2015-02-18
Homeodomain (100%) (view alignment) Ubx (P83949) exd (P40427) FRUIT FLY 4UUS_A 54.39 1.0E-12 2.55Å - 2015-02-18
Homeodomain (100%) (view alignment) Antp (Q24645) - FRUIT FLY 1AHD_P 51.61 4.0E-13 - 1993-10-31
Homeodomain (100%) (view alignment) Abd-B (P09087) exd (P40427) FRUIT FLY 5ZJR_A 68.42 5.0E-17 3.03Å - 2018-08-29
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 9ANT_B 54.24 7.0E-13 2.4Å - 1998-10-14
Homeodomain (100%) (view alignment) Abd-B (P09087) exd (P40427) FRUIT FLY 5ZJT_A 68.42 5.0E-17 2.4Å - 2018-08-29
Homeodomain (100%) (view alignment) HOXB13 (Q92826) MEIS1 (O00470) HUMAN 5EGO_B 58.62 8.0E-13 2.54Å - 2016-11-09
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EEA_B 58.62 8.0E-13 2.19Å - 2016-10-26
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EF6_J 58.62 6.0E-13 2.98Å - 2017-02-08
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 4XID_A 54.24 7.0E-13 2.7Å - 2015-11-25
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EF6_G 58.62 6.0E-13 2.98Å - 2017-02-08
Homeodomain (100%) (view alignment) Scr (P09077) exd (P40427) FRUIT FLY 2R5Y_A 49.25 7.0E-14 2.6Å - 2008-02-05
Homeodomain (99%) (view alignment) CDX2 (Q99626) - HUMAN 5LTY_M 50 1.0E-11 2.66Å - 2017-05-31
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 5JLX_A 54.24 7.0E-13 2.748Å - 2016-06-22
Homeodomain (100%) (view alignment) (Q7KSY7) - FRUIT FLY 2HOA_A 51.61 4.0E-13 - 1993-10-31
Homeodomain (100%) (view alignment) HOXC9 (P31274) - HUMAN 2MSY_A 60.29 2.0E-20 - 2015-09-16
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 4XIC_D 54.24 7.0E-13 2.69Å - 2015-11-25
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 5JLW_D 54.24 7.0E-13 2.088Å - 2016-06-22
Homeodomain (99%) (view alignment) CDX2 (Q99626) - HUMAN 6ES3_M 50 2.0E-11 2.18Å - 2018-03-21
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EEA_G 58.62 8.0E-13 2.19Å - 2016-10-26
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EEA_J 58.62 8.0E-13 2.19Å - 2016-10-26
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EEA_A 58.62 8.0E-13 2.19Å - 2016-10-26
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EDN_B 56.92 5.0E-15 3.2Å - 2016-11-09
Homeodomain (99%) (view alignment) CDX2 (Q99626) - HUMAN 6ES3_K 50 2.0E-11 2.18Å - 2018-03-21
Homeodomain (99%) (view alignment) CDX2 (Q99626) - HUMAN 5LTY_K 50 1.0E-11 2.66Å - 2017-05-31
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EDN_A 56.92 5.0E-15 3.2Å - 2016-11-09
Homeodomain (100%) (view alignment) Ubx (P83949) exd (P40427) FRUIT FLY 4UUS_E 54.39 1.0E-12 2.55Å - 2015-02-18
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EDN_G 56.92 5.0E-15 3.2Å - 2016-11-09
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 1HOM_A 51.61 7.0E-13 - 1993-10-31
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 5JLX_D 54.24 7.0E-13 2.748Å - 2016-06-22
Homeodomain (100%) (view alignment) Hoxa13 (Q62424) - MOUSE 2LD5_A 62.07 1.0E-14 - 2011-08-10
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 4XIC_A 54.24 7.0E-13 2.69Å - 2015-11-25
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EF6_B 58.62 6.0E-13 2.98Å - 2017-02-08
Homeodomain (100%) (view alignment) HOXB13 (Q92826) - HUMAN 5EF6_A 58.62 6.0E-13 2.98Å - 2017-02-08
Homeodomain (90%) (view alignment) Antp (P02833) - FRUIT FLY 1SAN_A 55.36 4.0E-13 - 1994-04-30
Homeodomain (99%) (view alignment) CDX1 (P47902) - HUMAN 5LUX_L 52.54 7.0E-11 3.23Å - 2017-05-17
Homeodomain (100%) (view alignment) HOXB13 (Q92826) TEAD4 (Q15561) HUMAN 5NO6_B 58.62 6.0E-13 2.88Å - 2018-05-16
Homeodomain (100%) (view alignment) Antp (P02833) - FRUIT FLY 9ANT_A 54.24 7.0E-13 2.4Å - 1998-10-14
Homeodomain (100%) (view alignment) ftz (P02835) - FRUIT FLY 1FTZ_A 55.17 9.0E-13 - 1994-05-31
Homeodomain (100%) (view alignment) PDX1 (P70118) - GOLDEN HAMSTER 2H1K_B 56.9 5.0E-14 2.42Å - 2007-03-20
Homeodomain (100%) (view alignment) HOXC9 (P31274) GMNN (O75496) HUMAN 2LP0_A 68.33 6.0E-20 - 2012-06-06