Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

tpl (P31013) - Overview - Molecular Target Synopsis

Protein


tpl, Tyrosine phenol-lyase
Enzyme Classification 4.1.99.2
UniProt P31013

Also Known as TPL_CITFR, tpl

Homotetramer.

6ECG
CITROBACTER FREUNDII TYROSINE PHENOL-LYASE F448A MUTANT COMPLEXED WITH L-METHIONINE
RCSB/PDB
Inspect Structure
See all 3D Structures for tpl

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
456P31013-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project tpl has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For tpl there are:
16 structures (34 chains) solved
14 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis