Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

PTPN6 (P29350) - Pathways - Molecular Target Synopsis

Data acquired from 36 pathway associations found
Pathway Name Source
Antigen activates B Cell Receptor (BCR) leading to generation of second messengersReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
CD22 mediated BCR regulationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Costimulation by the CD28 familyReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
GPVI-mediated activation cascadeReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Growth hormone receptor signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Interferon alpha/beta signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Interferon gamma signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Interleukin receptor SHC signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Interleukin-3, Interleukin-5 and GM-CSF signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Interleukin-37 signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Neutrophil degranulationReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
PD-1 signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
PECAM1 interactionsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Platelet sensitization by LDLReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Regulation of IFNA signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Regulation of IFNG signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Regulation of KIT signalingReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
Signal regulatory protein family interactionsReactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017
B cell activationPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
BCRNetPath 12/2011
EGFR1NetPath 12/2011
FGF signaling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
IL-3 Signaling Pathwaywikipathways
IL-4 signaling pathway(JAK1 JAK3 STAT6) ( IL-4 signaling(JAK1 JAK3 STAT6) )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
IL2NetPath 12/2011
IL3NetPath 12/2011
IL4NetPath 12/2011
IL5NetPath 12/2011
Interferon-gamma signaling pathwayPANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model)
KitReceptorNetPath 12/2011
Negative regulation of (Phosphorylation of cytokine receptor) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
Negative regulation of (Phosphorylation of JAK) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram )INOH 4.0 (signal transduction and metabolic data), 22-MAR-2011
ProlactinNetPath 12/2011
RANKLNetPath 12/2011
T-Cell Receptor and Co-stimulatory Signalingwikipathways
TCRNetPath 12/2011