Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SUA7 (P29055) - Overview - Molecular Target Synopsis

Protein


SUA7, Transcription initiation factor IIB
UniProt P29055

Also Known as TF2B_YEAST, SUA7

General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II.

6GYL
STRUCTURE OF A YEAST CLOSED COMPLEX WITH DISTORTED DNA (CORE CCDIST)
RCSB/PDB
Inspect Structure
See all 3D Structures for SUA7

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
345P29055-1

Sub-cellular localization


UniProt: SUA7 is active in the following subcellular-locations: nucleus.
GO terms: SUA7 is active in the following subcellular-locations: nucleus, transcriptional preinitiation complex.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SUA7 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For SUA7 there are:
15 structures (15 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis