Molecular Target Synopsis
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tgt (P28720) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 07/05/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 07/05/2019)


Chains assessed147
Chains with at least one site assessed as druggable using the strict criteria104
Chains with at least one site assessed as druggable using the relaxed criteria146


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
5V3C_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.47 78.3 29.2 Yes No
2 empty 2.11 61.3 28.9 No No
3 bound 2.2 71.9 22.8 No No
4 empty 1.93 64 21.8 No No
5 bound 1.89 70.2 12.2 No No
6 empty 2.77 68.3 21 No No
7 empty 2.45 65.6 17.9 No No
8 empty 2.24 61.2 15.8 No No
9 bound 2.41 59.7 15.9 No No
10 empty 2.12 59.2 14.6 No No
1R5Y_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 66 39.2 Yes No
2 bound 1.79 80.7 17.4 Yes Yes
3 empty 2.28 71.8 18.4 No No
4 empty 1.77 76.4 12.6 No No
5 empty 2.21 63.6 16.2 No No
6 empty 2.37 59.9 15.9 No No
7 empty 1.92 59.9 12 No No
8 empty 2.05 70.8 7.9 No No
9 empty 2.07 58 13.9 No No
10 empty 2.42 68.4 10.1 No No
4FPS_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.53 78.4 20.6 Yes No
2 empty 2 65.1 32.8 No No
3 empty 1.85 74.9 12 No No
4 empty 2.03 68.8 18.5 No No
5 empty 2.44 72.8 11.5 No No
6 bound 2.37 57.7 16.4 No No
7 empty 2.08 58.8 15 No No
8 empty 2.38 69.1 9.1 No No
9 empty 2 60.8 12.8 No No
10 empty 1.94 64.2 12.6 No No
1P0B_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 80.8 23.3 Yes Yes
2 empty 2.38 64.4 42.9 No No
3 empty 2.47 64.9 21.5 No No
4 empty 2.36 66.6 25.2 No No
5 empty 1.91 73.9 15 No No
6 empty 2.13 58.4 15.2 No No
7 empty 2.43 59 15.8 No No
8 empty 2.49 55.1 17.3 No No
9 empty 2.25 63.6 12.9 No No
10 empty 1.93 77.5 8.3 No No
4Q8O_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 69.1 42.2 Yes Yes
2 bound 2.1 69.7 24.6 No No
3 empty 1.65 56.9 22 No No
4 bound 1.75 72.7 14.3 No No
5 empty 2.15 61.7 17.2 No No
6 empty 2.17 66.6 12.6 No No
7 bound 2.4 56 15.7 No No
8 empty 2.18 58.1 12.5 No No
9 empty 2.05 77.6 7.1 No No
10 empty 2.03 71.1 8 No No
3EOS_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.09 66.5 41.9 Yes No
2 bound 1.81 79 19 Yes Yes
3 empty 2.15 66.4 25 No No
4 empty 1.84 85.4 11.8 Yes No
5 empty 1.88 75.7 12.6 No No
6 empty 2.13 62.6 16.6 No No
7 empty 1.86 60.4 13.4 No No
8 empty 2.05 51.1 15.2 No No
9 empty 2.51 64.7 14.3 No No
10 empty 2.15 68.3 9.7 No No
5UTJ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 72.1 34.6 Yes Yes
2 empty 2.3 65.3 43.2 No No
3 empty 2.15 62.2 23.3 No No
4 empty 1.84 75.3 14.8 No No
5 empty 2.22 63.2 16.2 No No
6 empty 2.44 60.7 16.9 No No
7 empty 2.32 58.4 16.2 No No
8 empty 2.36 58.7 15.9 No No
9 empty 2.3 67.3 9.1 No No
10 empty 1.9 79.8 8.8 No No
5LPT_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.57 69.9 41.5 Yes Yes
2 empty 2.01 58 21.3 No No
3 empty 1.79 70.1 17.1 No No
4 empty 2.05 72.5 10.9 No No
5 empty 2.18 65.6 18.6 No No
6 empty 1.63 71.5 8.7 No No
7 empty 2.1 61 14.1 No No
8 empty 2.09 78.1 8.1 No No
9 empty 2.38 62 14.4 No No
10 empty 2.56 68.2 9.3 No No
2Z1W_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.25 67.2 41.9 Yes Yes
2 bound 1.44 78.7 28.1 Yes Yes
3 empty 2.2 67.9 23.9 No No
4 bound 2.01 75.3 12.9 No No
5 empty 2.05 59.5 18.4 No No
6 empty 2.13 63.3 16.3 No No
7 bound 2.36 63.4 15.8 No No
8 empty 2.12 49.7 15.5 No No
9 empty 1.92 78.2 8.7 No No
10 empty 2.25 72.2 6.5 No No
1Q2S_C Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 77.6 29.7 Yes Yes
2 empty 1.93 62.7 34.2 No No
3 empty 1.96 71.3 12.5 No No
4 empty 2.42 62.5 18.7 No No
5 empty 2.43 63.6 24.2 No No
6 empty 2.13 61.2 20.8 No No
7 empty 2.24 63.3 15.1 No No
8 empty 2.4 58.2 16.4 No No
9 empty 2.64 75.9 9.8 No No
10 empty 2.87 64.6 16.2 No No
1Q2S_D Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.83 70.1 52.3 Yes Yes
2 empty 2.02 68.1 22.2 No No
3 empty 2.37 64.4 32.5 No No
4 empty 2.13 72.7 14 No No
5 empty 2.4 65 16.1 No No
6 empty 1.79 68.3 12.7 No No
7 empty 2.31 64.7 15.5 No No
8 empty 2.32 65.1 12.7 No No
9 empty 2.64 52.6 13.2 No No
10 empty 2.02 80 8.4 No No
1ENU_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.76 71.7 42 Yes Yes
2 empty 2.22 66.6 25.7 No No
3 empty 2.34 64.5 24.3 No No
4 empty 1.96 73.8 15.2 No No
5 empty 2.26 71.6 15 No No
6 empty 2.53 61.8 14.9 No No
7 empty 2.15 65.9 19.8 No No
8 empty 2.07 62.3 17 No No
9 empty 2.38 60.9 15.6 No No
10 empty 2.06 78.2 8.6 No No
4Q8N_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.61 73.7 38.7 Yes Yes
2 bound 2.13 66.1 42.8 No No
3 empty 1.73 77.6 19.5 No No
4 bound 1.89 73.9 13.4 No No
5 empty 1.95 62 17.8 No No
6 empty 2.26 57.1 18.7 No No
7 bound 2.37 56.4 15.7 No No
8 empty 2.02 67.9 8 No No
9 empty 1.96 81.5 7.8 No No
10 empty 2.07 77.2 6.8 No No
1K4G_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.61 72.8 40.6 Yes Yes
2 empty 2.33 67.8 32.3 No No
3 empty 2.38 67.4 24.8 No No
4 empty 2.07 73.4 14.2 No No
5 empty 2.51 63.1 19.5 No No
6 empty 2.17 73.1 10.6 No No
7 empty 2.02 60 17.6 No No
8 empty 2.11 63.5 14.4 No No
9 empty 2.37 58.1 15.9 No No
10 empty 2.12 75.6 8.3 No No
1Y5V_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.46 73 22.4 Yes No
2 bound 2.2 70.4 25.3 No No
3 empty 1.84 59.2 14.2 No No
4 empty 1.86 55.7 19.2 No No
5 empty 1.7 67 12.9 No No
6 empty 1.9 66 12.5 No No
7 empty 2.25 53.2 15.2 No No
8 empty 2.41 58.1 12.4 No No
9 bound 2.31 59.3 9.7 No No
10 empty 2.01 43.7 11.2 No No
4HVX_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.49 78 21.3 Yes No
2 bound 1.91 74.4 11.8 No No
3 empty 1.67 63.1 17.3 No No
4 empty 1.85 69 15.5 No No
5 empty 2.29 62.8 16.4 No No
6 empty 2.04 72.6 14.3 No No
7 empty 2.13 69.7 12.4 No No
8 bound 2.35 61.2 16.2 No No
9 empty 2.22 62.1 14.7 No No
10 empty 1.4 54.9 10.9 No No
1Q2R_D Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.06 80.8 25.8 Yes Yes
2 empty 2.08 65.8 37.4 No No
3 empty 1.96 72.8 16.5 No No
4 empty 2.31 66.1 15.4 No No
5 empty 2.18 65.9 16.3 No No
6 empty 2.18 64.9 16.9 No No
7 empty 1.73 69.3 10.7 No No
8 empty 2.45 54.3 19.5 No No
9 empty 2.2 58.8 13 No No
10 empty 2.03 76.6 7.8 No No
4FSA_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.65 69.9 36 Yes No
2 empty 1.75 60.8 22.4 No No
3 empty 1.86 75 12.9 No No
4 empty 2.27 72.2 11.4 No No
5 empty 2.22 72.3 12.5 No No
6 bound 2.36 60.1 15.7 No No
7 empty 2.09 59.7 13.5 No No
8 empty 2.07 79.7 8 No No
9 empty 2.17 67.3 9 No No
10 empty 2.07 69.1 8.5 No No
4L56_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.8 74 29.4 Yes Yes
2 empty 1.54 70.8 18.6 No No
3 bound 1.97 68.2 20.7 No No
4 bound 1.76 66 13.5 No No
5 bound 2.21 64.6 12.4 No No
6 bound 2.09 66.4 16.9 No No
7 empty 1.89 73.6 10.5 No No
8 empty 1.88 50 12.4 No No
9 empty 2.18 46.3 12.4 No No
10 empty 2.19 75.4 6.9 No No
2NSO_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.55 73.2 40 Yes Yes
2 empty 1.86 61.7 24.7 No No
3 empty 2.33 72 22 No No
4 empty 2.03 73.8 12.2 No No
5 empty 2.41 62.6 20.4 No No
6 empty 2.17 62.2 15.7 No No
7 empty 2.09 56.4 19.3 No No
8 bound 2.4 58.9 15.6 No No
9 empty 1.94 78.6 7.9 No No
10 empty 2.32 72.1 6.3 No No
1WKD_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 71.2 41.2 Yes Yes
2 empty 2.5 65.3 20.4 No No
3 empty 1.99 73.8 13.7 No No
4 empty 2.07 65.2 17.2 No No
5 empty 2.4 59.6 17 No No
6 empty 1.98 68.2 12.8 No No
7 empty 2.25 63.1 12.9 No No
8 empty 2.4 57.2 16.1 No No
9 empty 2.2 59.9 12.5 No No
10 empty 2.17 77.4 8.2 No No
2QZR_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 72.8 35.6 Yes No
2 bound 2.14 65.9 41.1 No No
3 empty 1.94 75 13 No No
4 empty 2.23 67.3 19.3 No No
5 empty 2.31 59.5 18 No No
6 bound 2.37 63 15.6 No No
7 empty 2.24 78.4 8 No No
8 empty 1.98 66.3 8.8 No No
9 empty 1.98 76.1 6.4 No No
10 empty 1.7 60 10.3 No No
3BLO_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 65.3 42.3 Yes No
2 bound 1.7 77.5 17.8 Yes No
3 empty 1.88 75.6 15.4 No No
4 empty 2.37 62.7 17.5 No No
5 empty 2.27 62.1 17.3 No No
6 empty 2.07 70.8 9.2 No No
7 bound 2.4 62.3 15.9 No No
8 empty 1.59 72.7 9.1 No No
9 empty 2.21 59.3 15.6 No No
10 empty 2.35 71 7 No No
4KWO_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.62 71.2 53.4 Yes Yes
2 bound 2.19 77.6 12.9 No No
3 empty 2.29 59.2 19.4 No No
4 empty 2.08 53.5 17.4 No No
5 empty 1.99 68.7 12.2 No No
6 empty 2 68.7 9.2 No No
7 empty 2.26 75.2 6.6 No No
8 empty 1.89 80.3 7.4 No No
9 empty 2.48 67.7 9.5 No No
10 empty 2.09 66.1 9 No No
4Q8V_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 69.2 52.2 Yes Yes
2 empty 2.05 70.3 24 No No
3 empty 1.67 60.6 21.6 No No
4 empty 2.04 77.6 13 No No
5 empty 2.31 58.4 18.8 No No
6 empty 2.16 60.7 15.9 No No
7 bound 2.38 58.1 15.7 No No
8 empty 1.98 62.9 14.4 No No
9 empty 1.88 79 7.4 No No
10 empty 2.06 72.3 8 No No
4Q8W_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.72 69.6 52 Yes Yes
2 empty 2.34 66.7 25.1 No No
3 bound 2.14 71 24.1 No No
4 empty 1.71 60.4 22.2 No No
5 empty 1.96 75.1 16 No No
6 empty 2.27 60.3 18.9 No No
7 empty 2.13 58.8 15.2 No No
8 bound 2.37 61.1 15.9 No No
9 empty 2.33 63.2 8.9 No No
10 empty 1.96 78.8 8.2 No No
1Q2S_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 75.5 30.1 Yes Yes
2 empty 2.21 68.8 25.8 No No
3 empty 1.95 71.8 15.3 No No
4 empty 2.55 67.2 18.8 No No
5 empty 2.21 62.8 22.2 No No
6 empty 1.86 61.6 14.6 No No
7 empty 2.23 61.8 23.1 No No
8 empty 2.38 58.8 16.1 No No
9 empty 2.18 63.1 16.2 No No
10 empty 2.52 73.1 11.6 No No
4GH1_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 78.2 31.6 Yes No
2 empty 2.18 72.4 24.8 No No
3 empty 1.95 64.3 22.6 No No
4 empty 1.76 59.7 22.4 No No
5 empty 1.91 74 12.8 No No
6 empty 2.04 59.8 22.3 No No
7 empty 1.87 76.7 8.2 No No
8 empty 2.1 63.7 11.1 No No
9 bound 2.33 58.9 8.8 No No
10 empty 2.07 61.9 11.5 No No
1P0E_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.36 62.7 40 Yes No
2 bound 2.02 81.2 20.5 Yes Yes
3 empty 1.89 72.3 14 No No
4 empty 2.09 62.2 16.6 No No
5 empty 2.38 64.9 13.6 No No
6 empty 1.84 60.4 13.9 No No
7 empty 2.33 62.6 22.9 No No
8 empty 1.93 60.1 17.5 No No
9 empty 1.91 68.2 11 No No
10 empty 2.36 55.5 16 No No
1F3E_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.72 75.3 28.5 Yes Yes
2 empty 2.23 67.7 29.5 No No
3 empty 2.37 66.5 24.5 No No
4 empty 1.96 74 18 No No
5 empty 2.51 64.8 22.6 No No
6 empty 2.19 70.3 15.8 No No
7 empty 2.05 63.4 17.5 No No
8 empty 2.35 61.3 16.8 No No
9 empty 1.99 77.8 8 No No
10 empty 2.56 59.8 11.1 No No
4GI4_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.63 80.6 28.1 Yes Yes
2 empty 1.8 60.6 25.9 No No
3 empty 1.77 70.4 15.3 No No
4 empty 2.19 66.6 16.3 No No
5 empty 2.03 68.2 17.4 No No
6 empty 2 60.5 16.7 No No
7 empty 2.14 66.1 12 No No
8 empty 1.9 62 8.5 No No
9 empty 2.12 76.6 10.6 No No
10 empty 1.68 65.2 8.4 No No
3UVI_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.71 70.5 44.5 Yes Yes
2 bound 2.14 72.3 24.5 No No
3 empty 2.03 57.7 26 No No
4 empty 1.91 76 11.8 No No
5 empty 2.37 61.6 19.2 No No
6 empty 2.17 62.8 17.2 No No
7 empty 1.91 77.7 7.3 No No
8 empty 1.95 65.9 8 No No
9 empty 2.08 74.2 6.6 No No
10 bound 2.68 67.2 7.7 No No
5I06_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.65 69.8 22.9 Yes Yes
2 empty 2 67.9 21.8 No No
3 bound 2 72.7 14.8 No No
4 empty 2.12 57.4 18.5 No No
5 empty 1.66 62.3 11.4 No No
6 bound 1.96 66.2 13.1 No No
7 empty 1.91 64 16.3 No No
8 bound 2.02 63.2 12.5 No No
9 empty 2.15 65.1 10.9 No No
10 empty 2.01 51.1 13.6 No No
1Q63_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.65 76.5 22.7 Yes No
2 empty 2.31 67.4 42.6 No No
3 empty 2.41 64.8 24.4 No No
4 empty 1.95 74.9 17 No No
5 empty 2.32 57.4 15.1 No No
6 empty 2.21 64.7 18.3 No No
7 empty 2.17 64.2 11.9 No No
8 empty 2.42 54.5 11.9 No No
9 empty 2.43 62.1 15.8 No No
10 empty 2.31 52.7 17.3 No No
1PUD_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 71.4 30.3 Yes No
2 empty 2.06 61.7 26.8 No No
3 empty 2.51 67.3 20.4 No No
4 empty 2.05 75 15.3 No No
5 empty 2.13 69.2 21.3 No No
6 empty 2.2 62.2 17.1 No No
7 empty 2.36 59.2 16.8 No No
8 empty 2.22 62.7 14.3 No No
9 empty 2.4 61 16.1 No No
10 empty 2.22 61.4 12.6 No No
3SM0_A Queuine tRNA-ribosyltransferase No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.56 70.7 19.8 No No
2 bound 2.12 67 26.7 No No
3 empty 1.89 65.9 16.9 No No
4 empty 1.59 61.9 14.2 No No
5 empty 1.74 67.6 13.3 No No
6 empty 1.87 57.1 16.5 No No
7 empty 2.1 48.7 12 No No
8 empty 2.08 59.4 12.8 No No
9 bound 2.33 60.9 9 No No
10 empty 2.19 65.3 10.3 No No
3BLD_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 73.5 30.6 Yes No
2 empty 1.59 61.1 20 No No
3 empty 1.92 61.8 25.2 No No
4 empty 1.93 74.1 13.4 No No
5 empty 2.18 72.7 16.8 No No
6 empty 2.25 62.7 19 No No
7 bound 2.43 61.6 16.3 No No
8 empty 2.06 51.8 12.2 No No
9 empty 2.44 70.9 12.3 No No
10 empty 1.95 78.5 8.7 No No
5SW3_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 65.5 38.7 Yes No
2 bound 1.86 77.6 25.6 No No
3 empty 2.16 68.5 23.4 No No
4 bound 1.91 74.1 13.1 No No
5 bound 2.35 63.1 19.5 No No
6 empty 2.39 68.1 18.1 No No
7 empty 2.14 57.4 19 No No
8 bound 2.51 58.2 17.5 No No
9 empty 2.28 61.6 10.9 No No
10 empty 2.23 81.3 8.3 No No
3C2Y_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 65.2 42 Yes No
2 bound 1.65 71 40 No No
3 empty 2.07 76.3 14 No No
4 empty 2.17 74.4 12.7 No No
5 empty 2.04 60.8 17.2 No No
6 empty 2.41 65.3 16.2 No No
7 bound 2.38 59.6 15.8 No No
8 bound 2.04 55.6 15.3 No No
9 empty 1.93 80.6 8 No No
10 empty 2.23 71.4 6.4 No No
1P0D_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 75.5 36.9 Yes Yes
2 empty 2.35 64.9 43.1 No No
3 empty 1.94 74.7 13.6 No No
4 empty 2.07 63.4 17 No No
5 empty 2.37 58.5 15.7 No No
6 empty 2.15 67.3 9.7 No No
7 empty 1.94 77.5 7.5 No No
8 empty 2.39 69.7 7.9 No No
9 empty 1.88 66.7 7.2 No No
10 empty 2.15 53.6 12.9 No No
4Q4S_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.76 68.1 39.9 Yes Yes
2 bound 2.24 64.9 42.1 No No
3 empty 1.98 74.5 15.1 No No
4 empty 2.14 61.4 17.2 No No
5 empty 2.29 62.1 19.8 No No
6 bound 2.31 58.4 15.6 No No
7 empty 2.25 55.7 11.9 No No
8 empty 2.01 66.8 9.8 No No
9 empty 2.05 76.3 7.3 No No
10 empty 2.19 67.4 9.5 No No
1OZQ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 70 55.2 Yes Yes
2 empty 2.03 74.5 12.2 No No
3 empty 2.15 61.9 21.9 No No
4 empty 2.03 68.6 12 No No
5 empty 2.13 57.6 23.3 No No
6 empty 1.99 62 17.6 No No
7 empty 2.42 57.6 15.8 No No
8 empty 2.19 63 12.2 No No
9 empty 1.96 75.6 7.7 No No
10 empty 2.18 73.8 6.7 No No
3UNT_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.51 75.2 38.9 Yes Yes
2 empty 2.03 61 31.1 No No
3 empty 1.8 73.2 14.2 No No
4 empty 2.16 61.6 17.7 No No
5 empty 2.23 62.5 17.7 No No
6 bound 2.06 73 10.3 No No
7 bound 2.38 59.9 16 No No
8 empty 2.06 58.1 16.1 No No
9 empty 2.27 77.2 8.4 No No
10 empty 1.99 81.2 7.1 No No
1K4H_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.51 70.6 43.5 Yes Yes
2 empty 2.14 66.7 29.3 No No
3 empty 2.35 67.3 24.3 No No
4 empty 2.03 72.7 15.2 No No
5 empty 2.32 65.6 19.7 No No
6 empty 2.2 71.2 16.3 No No
7 empty 2.05 60.7 16.1 No No
8 empty 2.35 60.8 15.7 No No
9 empty 2.15 77.5 7.9 No No
10 empty 2.31 62.5 17 No No
5LPO_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.47 69 37.1 Yes Yes
2 empty 1.98 67.1 23.7 No No
3 empty 2.04 62.1 26.2 No No
4 bound 1.81 73 12.7 No No
5 empty 2.11 64.3 17.8 No No
6 empty 1.95 68.9 12.4 No No
7 bound 2.1 60.9 16.5 No No
8 empty 2.19 53.5 14.8 No No
9 empty 2.09 64.3 10.1 No No
10 empty 2.18 66.5 10.7 No No
1WKE_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.78 71.2 43.5 Yes Yes
2 empty 2.56 66.7 19.3 No No
3 empty 2.06 74.2 14.4 No No
4 empty 2.27 70.1 25.1 No No
5 empty 2.11 63.8 17 No No
6 empty 2.28 58.9 16 No No
7 empty 2.21 60.1 14.2 No No
8 empty 2.39 59.9 15.9 No No
9 empty 2.2 60.9 12.3 No No
10 empty 2.09 78.2 7.5 No No
5JGM_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 76.1 23.7 Yes Yes
2 bound 2.07 65.7 26.2 No No
3 bound 1.74 71.5 12.9 No No
4 empty 2.38 64.3 15.6 No No
5 empty 2.23 59 19.1 No No
6 empty 1.6 61.3 13.9 No No
7 empty 1.97 65 16.1 No No
8 empty 1.93 67.7 12.2 No No
9 empty 2.11 49.5 14.1 No No
10 empty 2.05 54 13.8 No No
5J9N_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 71.6 40 Yes Yes
2 bound 2.09 71.8 23.3 No No
3 empty 1.79 60.8 21.2 No No
4 empty 1.91 74.6 10.8 No No
5 empty 1.85 58.7 16.7 No No
6 bound 2.39 59.8 15.7 No No
7 empty 2.17 53.3 12.1 No No
8 empty 2.08 77.8 7.6 No No
9 empty 2.53 67.4 8.4 No No
10 empty 2.34 75.4 6.1 No No
3BLL_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 73.4 31.2 Yes No
2 empty 1.73 65.8 27.9 No No
3 empty 2.03 72.8 11.8 No No
4 empty 1.48 58 19.8 No No
5 empty 2.2 58.9 18.3 No No
6 empty 2.13 73.3 12.2 No No
7 empty 2.07 72.4 12.2 No No
8 empty 2.4 72 6.5 No No
9 empty 1.99 78.6 8.2 No No
10 empty 2.12 55.9 16.7 No No
1PXG_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.64 68.3 34.5 Yes No
2 bound 2.2 66.8 25.8 No No
3 empty 1.77 60.1 15.5 No No
4 empty 1.97 62.7 15.7 No No
5 empty 1.94 69.5 14.2 No No
6 empty 2.11 57 18.8 No No
7 empty 2.13 55.9 17.3 No No
8 empty 2.25 60.5 12.3 No No
9 empty 2.08 52 13.2 No No
10 empty 1.44 59.7 12.8 No No
1Q4W_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.71 72.6 40.1 Yes Yes
2 empty 2.38 67.7 25 No No
3 empty 2.04 73.8 15.1 No No
4 empty 2.23 67.4 18.3 No No
5 empty 2.16 70.7 12.8 No No
6 empty 2.17 61.9 18.8 No No
7 empty 2.44 62.2 15.7 No No
8 empty 2.57 64.5 12.2 No No
9 empty 2.08 79.7 8 No No
10 empty 2.24 65.8 8.3 No No
5J9M_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 69.8 51.8 Yes Yes
2 bound 2.11 64.5 41.3 No No
3 empty 2.04 68.8 24.6 No No
4 bound 1.78 77.5 11.8 No No
5 empty 2.26 61 19.7 No No
6 bound 2.39 62.5 15.7 No No
7 empty 1.87 78.2 7.2 No No
8 empty 2.02 62.7 9.6 No No
9 empty 2.02 71.3 7.7 No No
10 empty 2.06 73 6.3 No No
6FMN_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 73.3 43.9 Yes Yes
2 empty 2.26 64.5 24.9 No No
3 bound 2.19 71.7 21.2 No No
4 empty 1.69 61.7 21.8 No No
5 empty 1.89 77.1 13.8 No No
6 empty 2.25 65 18.6 No No
7 empty 2.33 60 18.1 No No
8 bound 2.37 58.9 16.1 No No
9 empty 2.53 66.7 11 No No
10 empty 2.22 78.9 8.6 No No
1Q2R_C Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 76.2 29.1 Yes No
2 empty 2.28 64.3 42.2 No No
3 empty 1.96 70.3 15.6 No No
4 empty 2.5 60.8 24.6 No No
5 empty 2.45 58.9 17.7 No No
6 empty 2.38 57.7 16.5 No No
7 empty 2.55 69.8 10.6 No No
8 empty 2.11 57.7 14 No No
9 empty 2.17 64.7 11.4 No No
10 empty 2.18 64 17.3 No No
2PWU_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.76 77.9 22 Yes Yes
2 empty 2.09 65.4 42 No No
3 empty 1.91 68.6 16.2 No No
4 empty 1.8 75.9 15.2 No No
5 empty 1.59 69.4 14.8 No No
6 empty 2.35 65.3 22.3 No No
7 bound 2.37 58.3 15.9 No No
8 empty 2.34 55.1 17.4 No No
9 empty 2.37 66.2 9.3 No No
10 empty 1.96 79.4 7.6 No No
2Z1V_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.88 72.2 46.5 Yes Yes
2 empty 1.94 64 28.4 No No
3 empty 2.22 63.1 24.6 No No
4 empty 2.1 77.4 15.3 No No
5 bound 2.34 71.6 21.1 No No
6 empty 2.01 58.4 16.4 No No
7 empty 2.29 65 10.4 No No
8 bound 2.37 59.9 15.8 No No
9 empty 1.94 80.7 8.5 No No
10 empty 2.59 64.4 14.8 No No
4LEQ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 81.3 21.1 Yes Yes
2 bound 2.12 72.8 22.8 No No
3 empty 2.27 63.2 24.1 No No
4 empty 2.36 64 19.7 No No
5 empty 1.8 61.1 21.9 No No
6 empty 1.76 74.9 11.6 No No
7 empty 1.98 57.2 15.7 No No
8 bound 2.33 59.9 15.7 No No
9 empty 2.09 56.8 16.6 No No
10 empty 1.96 79.3 8 No No
5I07_B Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 68.5 36.7 Yes Yes
2 empty 2.03 51 19.9 No No
3 empty 1.82 72.9 16.3 No No
4 empty 2.12 61.7 18.5 No No
5 empty 2.05 65.3 15 No No
6 bound 1.8 71.6 10.1 No No
7 empty 2.1 50.4 11.8 No No
8 empty 1.94 77.3 8.1 No No
9 empty 2.02 66.5 8.3 No No
10 empty 1.49 52.8 9.6 No No
4Q8M_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.76 74 38.8 Yes Yes
2 bound 2.14 65.3 42.2 No No
3 empty 2.04 73.5 17.9 No No
4 empty 2.38 63.3 19.4 No No
5 empty 2.48 61.6 17.1 No No
6 empty 2.18 62 11.5 No No
7 bound 2.33 58.2 16.2 No No
8 empty 1.85 58.4 16.6 No No
9 empty 2.11 82.1 7.2 No No
10 empty 1.93 68.2 7.9 No No
2NQZ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.57 80.3 19.8 Yes Yes
2 empty 1.64 61.5 21.9 No No
3 bound 1.89 74.3 11.8 No No
4 empty 2.29 58.5 18.9 No No
5 empty 2.08 69.7 16.4 No No
6 empty 2.01 71.9 12 No No
7 empty 2 66.3 15.5 No No
8 empty 2.12 57.9 13.2 No No
9 empty 2.09 59 20.1 No No
10 bound 2.37 60.1 15.8 No No
4Q8U_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 80.4 21.8 Yes Yes
2 bound 2.12 71.8 24.1 No No
3 empty 1.63 62.7 21.5 No No
4 empty 2.12 68.4 23.5 No No
5 empty 2.09 63.2 16.1 No No
6 empty 1.99 75.5 13.2 No No
7 empty 2.35 57.8 18.5 No No
8 empty 2.16 61.6 12.5 No No
9 bound 2.38 62 15.5 No No
10 empty 2.17 55.7 17.4 No No
4Q8T_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.91 70.5 40.3 Yes Yes
2 bound 2.21 72.3 23.3 No No
3 empty 1.7 62.5 21.2 No No
4 empty 2.12 67.6 22.6 No No
5 empty 2 73.8 12.4 No No
6 empty 2.34 59.2 19 No No
7 bound 2.35 59.2 15.6 No No
8 empty 2.17 55.4 14.5 No No
9 empty 2.11 77.3 8.7 No No
10 empty 2.47 69.1 13.5 No No
5I00_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.55 73.1 38.6 Yes Yes
2 bound 2.03 71.3 24 No No
3 empty 1.56 61.6 21.4 No No
4 bound 1.88 75.2 12.7 No No
5 empty 2.19 62.3 19.1 No No
6 empty 2.09 72.6 11.5 No No
7 empty 2.03 54.4 16.8 No No
8 bound 2.43 59.9 15.9 No No
9 empty 1.92 63.6 10.6 No No
10 empty 2.39 68.8 11.4 No No
4H7Z_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.58 75.5 41.2 Yes No
2 bound 2.22 71.7 21.2 No No
3 empty 1.68 60.5 21.8 No No
4 empty 1.87 73.6 13 No No
5 empty 2.5 59.9 19.8 No No
6 empty 2.4 62.5 17.6 No No
7 empty 2.02 64.7 11.8 No No
8 bound 2.42 60.2 15.9 No No
9 empty 2.12 56.7 15.5 No No
10 empty 2.39 66.7 13 No No
5LPQ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.61 69.5 45.8 Yes Yes
2 empty 2.41 60.6 22.9 No No
3 empty 1.88 71.3 17.8 No No
4 empty 1.58 72.4 10.3 No No
5 empty 2.02 60.8 15.4 No No
6 empty 2.12 66.6 8.4 No No
7 empty 2.07 67.7 8.2 No No
8 empty 1.81 76.7 7.6 No No
9 empty 2.09 51.5 9.3 No No
10 empty 2.68 73.8 7.3 No No
2OKO_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 79.6 21.4 Yes Yes
2 bound 2.14 65.2 42.7 No No
3 empty 2.39 65.2 22.2 No No
4 bound 1.97 76.4 12.2 No No
5 empty 1.97 60 17.8 No No
6 bound 2.38 59.5 15.7 No No
7 empty 2.33 58.8 17 No No
8 empty 2.15 69.1 13 No No
9 bound 2.22 74.3 6.8 No No
10 bound 2.01 78.6 7.2 No No
5I03_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.51 74.4 31.2 Yes No
2 empty 2.23 69.4 32.1 No No
3 empty 1.96 65.3 25.7 No No
4 bound 2.01 74 12.3 No No
5 empty 2.17 65.8 18.8 No No
6 bound 2.25 67.6 20.5 No No
7 empty 1.97 56.4 15.8 No No
8 empty 2.42 68.4 12.5 No No
9 empty 2.21 63.6 12.3 No No
10 empty 2.36 72.4 7.9 No No
5N6F_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 69.2 40.8 Yes Yes
2 bound 2.08 71.4 25.9 No No
3 empty 1.52 60.7 23.5 No No
4 empty 2.67 68.1 22.2 No No
5 bound 1.95 71.7 15.9 No No
6 empty 2.27 62.2 11.6 No No
7 empty 2.05 67.3 13 No No
8 empty 2.4 58.4 15.6 No No
9 empty 2.29 62.6 10.6 No No
10 empty 2.37 68 12.8 No No
3BL3_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.49 73 33.8 Yes No
2 empty 2.26 61.8 20.5 No No
3 empty 1.93 74.7 12.4 No No
4 empty 1.54 59.6 20.6 No No
5 empty 2.18 62.3 19.4 No No
6 empty 2.15 75.6 12.1 No No
7 empty 2.09 73.3 14.6 No No
8 empty 2.18 57.5 15.2 No No
9 empty 2.09 77.7 7.8 No No
10 bound 2.38 67.5 8.9 No No
1EFZ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 76 37.1 Yes Yes
2 empty 2.15 66 42.2 No No
3 empty 2.11 73.7 15.3 No No
4 empty 2.32 62.3 18.2 No No
5 empty 2.18 62.3 17.7 No No
6 empty 2.43 60.6 15.8 No No
7 empty 2.29 55.8 12.9 No No
8 empty 2.1 77.5 7.9 No No
9 empty 2.33 66 8.4 No No
10 empty 2.38 57.3 12.6 No No
2Z7K_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 71.2 41.6 Yes Yes
2 empty 2.27 65.5 42.2 No No
3 empty 1.72 76.3 12.9 No No
4 empty 2.21 62.8 16.7 No No
5 empty 2.27 66 13.2 No No
6 empty 2.16 88.7 15.4 Yes No
7 bound 2.35 57.5 16 No No
8 empty 2.16 58.1 15.9 No No
9 empty 1.9 78 8.6 No No
10 empty 2.29 64.5 9 No No
4PUJ_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 76.6 28.1 Yes No
2 bound 2.08 71.5 24.8 No No
3 empty 1.97 75.9 16.1 No No
4 empty 1.6 63.1 16.9 No No
5 empty 2.42 63.4 18 No No
6 empty 2.41 67.2 27 No No
7 empty 2.42 54.4 17.3 No No
8 empty 2.13 62.1 18.9 No No
9 empty 2.14 65.5 13.6 No No
10 bound 2.39 59.1 15.9 No No
5I02_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.73 72.5 42.3 Yes Yes
2 empty 2.08 68.2 25.6 No No
3 bound 2.15 76.1 12.9 No No
4 empty 2.3 67.8 17.7 No No
5 empty 2.01 54.8 16.1 No No
6 empty 2.12 64.3 13.6 No No
7 bound 2.09 75.7 6.4 No No
8 empty 1.89 81.6 7.9 No No
9 empty 2.23 68.5 7.8 No No
10 empty 1.91 66.9 9.6 No No
4GG9_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.65 78.1 23.1 Yes No
2 empty 2.06 64.3 32 No No
3 empty 2.09 64.7 23.3 No No
4 empty 1.82 74.7 11.9 No No
5 bound 2.12 69.6 14.7 No No
6 empty 2.06 57.1 21 No No
7 empty 1.52 65.5 12.5 No No
8 empty 2.18 65.4 12.4 No No
9 empty 2.02 65.7 7.7 No No
10 empty 1.94 80.9 9 No No
6FSO_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 70.7 38.6 Yes Yes
2 bound 1.74 70 12.9 No No
3 bound 2.13 69.2 19.3 No No
4 empty 1.58 62.5 12.3 No No
5 empty 1.98 55.8 12.2 No No
6 empty 2.21 56.7 16.9 No No
7 bound 1.94 64.1 11.2 No No
8 empty 1.48 55.9 10.3 No No
9 empty 2.14 52 12.9 No No
10 empty 2.15 69 12.3 No No
1Y5X_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.7 76.3 33.8 Yes Yes
2 empty 2.2 66 41.7 No No
3 empty 2.25 66 19.2 No No
4 empty 2.02 75 19.6 No No
5 empty 2.42 62.1 17.9 No No
6 empty 2.29 66.5 10.7 No No
7 empty 2.38 58.2 17.6 No No
8 empty 2.37 55.8 15.8 No No
9 empty 1.92 79.3 7.9 No No
10 empty 2.04 71.1 8.5 No No
3EOU_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.83 76.9 27.7 Yes No
2 bound 2.1 67.2 36.9 No No
3 empty 2.02 66.2 23.9 No No
4 empty 1.8 74.1 12.2 No No
5 empty 2.16 62.6 16.1 No No
6 bound 2.39 59.6 15.7 No No
7 empty 2.13 57.2 12.2 No No
8 empty 1.77 63.6 9.2 No No
9 empty 1.9 80.1 8 No No
10 empty 2.24 64.8 9.4 No No
4Q4Q_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 64.1 43.5 Yes No
2 bound 1.89 77.5 27.4 No No
3 empty 2.29 65.3 25.2 No No
4 bound 2.04 71.8 18.7 No No
5 empty 2.11 62.7 17.6 No No
6 empty 2.12 61.7 15.8 No No
7 bound 2.43 56.5 15.7 No No
8 empty 2.09 56.1 12.7 No No
9 empty 2.02 63.4 10.2 No No
10 empty 1.9 80.7 0 No No
3GE7_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 81 23.3 Yes Yes
2 empty 2.21 67.2 42.1 No No
3 empty 2.01 70.7 22.9 No No
4 empty 1.89 74 11.6 No No
5 empty 2.08 62 17.8 No No
6 bound 2.39 60.2 15.8 No No
7 empty 2.15 56.2 16.4 No No
8 empty 2.2 68.2 9.3 No No
9 empty 2 81.7 7.8 No No
10 empty 2.08 72.5 6.2 No No
5JT7_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.83 74.3 39.8 Yes Yes
2 bound 2.11 73.1 23.3 No No
3 empty 1.64 62 22.8 No No
4 empty 1.84 65.9 19.5 No No
5 empty 1.82 75.5 12.2 No No
6 empty 2.07 60.4 15.5 No No
7 empty 2.19 66.8 11.8 No No
8 empty 2.29 66.1 12.7 No No
9 bound 2.38 59.2 15.7 No No
10 empty 1.92 77.9 12.2 No No
4DY1_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.67 81.1 25.8 Yes Yes
2 empty 2.13 66.9 42.3 No No
3 empty 2.05 72.2 18 No No
4 empty 2.21 63.2 21.8 No No
5 empty 2.36 62.7 17.5 No No
6 empty 2.17 83.2 12.2 No No
7 empty 1.95 61.1 16.6 No No
8 empty 2.16 62 22.8 No No
9 empty 2.43 57.5 16.1 No No
10 empty 1.81 96.3 0 Yes No
5J9O_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.79 80.5 32.9 Yes Yes
2 bound 2.18 66 42.6 No No
3 empty 1.87 67.8 16.8 No No
4 empty 1.72 75.8 15.3 No No
5 empty 2.38 66.6 17.9 No No
6 empty 1.86 61.2 16.7 No No
7 bound 2.31 60.2 15.9 No No
8 empty 2.01 53.5 11.7 No No
9 empty 2.15 81.9 7.7 No No
10 empty 2.52 66.8 9.3 No No
5JGO_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 75.4 22.8 Yes Yes
2 bound 2.11 66.2 25.7 No No
3 bound 1.97 67.8 13.7 No No
4 empty 1.61 60.9 13.4 No No
5 empty 2.17 63.1 15.7 No No
6 empty 1.92 64.4 11.5 No No
7 empty 1.87 65.4 13.2 No No
8 empty 2.02 53.8 15.6 No No
9 bound 2.32 60.3 13 No No
10 empty 1.42 53.3 11.7 No No
4PUK_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 70.2 39.9 Yes Yes
2 bound 2.11 72.1 24 No No
3 empty 1.66 59.6 21.5 No No
4 bound 1.82 75 12.7 No No
5 empty 2.22 62.9 16.7 No No
6 empty 2.05 60.3 21.4 No No
7 bound 2.39 57.8 15.7 No No
8 empty 1.88 79.7 7 No No
9 empty 2.06 70.5 8.2 No No
10 empty 1.93 66.1 7.5 No No
5LPP_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 69.1 42.5 Yes Yes
2 empty 2.07 66.2 23.2 No No
3 empty 2.38 67.6 22.2 No No
4 empty 1.94 73.8 15.2 No No
5 empty 2.35 59 19.5 No No
6 empty 2.4 75.8 6.4 No No
7 empty 1.95 78.6 7.7 No No
8 empty 2.08 56 12.1 No No
9 empty 2.13 67.8 6 No No
10 empty 2.05 64.4 9.8 No No
1S39_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.71 73.1 38.2 Yes Yes
2 empty 2.07 62.4 26.8 No No
3 empty 2.43 64.2 23.4 No No
4 empty 1.96 76.6 16.1 No No
5 empty 1.98 72.7 9.9 No No
6 empty 2.32 72.1 13.2 No No
7 empty 2.05 63.3 16.3 No No
8 empty 2.4 62.7 15.8 No No
9 empty 2.39 67.4 14.5 No No
10 empty 2.24 52.4 12.6 No No
4Q4M_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 83.1 23 Yes Yes
2 empty 2.38 63.1 24.1 No No
3 empty 2.17 70.9 24 No No
4 empty 1.67 60.2 21.6 No No
5 empty 1.84 78.6 12.3 No No
6 empty 2.39 61.8 18.3 No No
7 empty 2.03 64.5 11.5 No No
8 bound 2.38 60.4 16.2 No No
9 empty 2.09 55 15.2 No No
10 empty 2.29 67 13.3 No No
4PUL_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.7 77.7 23.1 Yes No
2 empty 2.16 71.4 23.3 No No
3 empty 1.7 61.2 21.9 No No
4 empty 2.1 66.4 24.8 No No
5 empty 1.94 75.2 12.1 No No
6 bound 2.38 59.5 15.7 No No
7 empty 2.01 54.9 17.4 No No
8 empty 2.27 63.7 15.3 No No
9 empty 2.06 79.9 8.3 No No
10 empty 2.07 72.3 7.3 No No
4E2V_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 70.4 40.7 Yes Yes
2 empty 2.15 67.3 27.3 No No
3 empty 2.07 73.1 16.2 No No
4 empty 2.39 60.9 19.2 No No
5 bound 2.17 70.5 13.6 No No
6 empty 2.09 55.9 15.1 No No
7 bound 2.33 59.3 16.4 No No
8 empty 1.57 57.7 11.1 No No
9 empty 2.08 79.2 8 No No
10 empty 2.13 69.2 9.4 No No
4HSH_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.5 75.6 35 Yes Yes
2 bound 2.22 67.3 36.9 No No
3 bound 2.11 76 13.3 No No
4 empty 2.38 60.1 19.4 No No
5 empty 2.21 60.8 13.2 No No
6 empty 2.08 55.6 17 No No
7 empty 2.17 62.5 10.7 No No
8 bound 2.38 60.6 16.1 No No
9 empty 1.68 57.4 10.3 No No
10 empty 2.03 71.6 11 No No
4FR6_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 72.9 32.5 Yes Yes
2 empty 2.06 66.8 25.3 No No
3 empty 2.41 68.6 21.1 No No
4 empty 1.9 75.3 12.4 No No
5 empty 2.01 55.6 15.7 No No
6 empty 2.07 67.4 13.8 No No
7 empty 2.58 75.6 7.9 No No
8 empty 1.85 80 8.9 No No
9 empty 2.58 57.8 12 No No
10 empty 2.51 69.6 8.8 No No
4GKT_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.72 76.9 30.8 Yes No
2 empty 2.11 68.5 29.2 No No
3 empty 1.74 61 22.3 No No
4 empty 1.95 73.2 11 No No
5 empty 2.19 69.7 12.8 No No
6 empty 2.2 73.3 12.3 No No
7 bound 2.37 60.1 15.7 No No
8 empty 2.05 57.3 15.8 No No
9 empty 2.01 77.6 11.3 No No
10 empty 2.39 76.1 7.6 No No
5JT5_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.96 68.7 51.7 Yes Yes
2 bound 2.17 65.9 42 No No
3 empty 2.52 68.4 23 No No
4 bound 1.86 74.7 14.9 No No
5 empty 2.4 60.3 19.7 No No
6 bound 2.31 61.2 15.6 No No
7 empty 2.48 69.4 8.4 No No
8 empty 2.09 77.6 7.2 No No
9 empty 2.1 63.6 8.2 No No
10 empty 2.43 68.5 6.7 No No
5UTI_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.27 66.6 42.2 Yes Yes
2 bound 1.92 78.5 29.6 No No
3 empty 2.23 70.5 24.2 No No
4 empty 1.91 72.3 13.7 No No
5 empty 2.29 66.8 17.5 No No
6 empty 2.43 60.3 16.7 No No
7 empty 2.52 60.1 17 No No
8 empty 2.12 55.6 12.8 No No
9 empty 1.79 79.2 8.3 No No
10 empty 2.06 73.8 7 No No
5EGR_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.49 68.7 37.2 Yes No
2 bound 2.13 69.5 22.8 No No
3 empty 1.74 60.5 22.6 No No
4 empty 1.9 73.1 13.7 No No
5 empty 2.01 60.6 16.1 No No
6 empty 2.09 55.1 16.6 No No
7 bound 2.37 59.1 15.8 No No
8 empty 1.8 78.2 8.2 No No
9 empty 2.38 67.4 8.5 No No
10 empty 2.02 63.9 9.2 No No
4JBR_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.62 74.2 36.6 Yes Yes
2 empty 1.89 69.1 16.6 No No
3 empty 1.63 56.6 21.9 No No
4 empty 1.79 63.5 15.1 No No
5 empty 2.18 64.2 14 No No
6 empty 2.38 68.1 10.8 No No
7 empty 1.94 67.6 8.8 No No
8 empty 2.09 61.2 14.5 No No
9 empty 1.94 65.1 10.9 No No
10 empty 1.83 68.4 9.7 No No
5JXQ_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 72 40.5 Yes Yes
2 bound 2.14 65.6 42 No No
3 empty 2.01 74.4 16.8 No No
4 empty 2 57.5 16.4 No No
5 empty 2.17 67.9 15.3 No No
6 empty 2.34 59.8 15.7 No No
7 empty 2.1 54.7 14.6 No No
8 empty 2.52 69.8 10.2 No No
9 empty 2.54 69.6 7.7 No No
10 empty 1.91 78.8 8.4 No No
1Q65_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.39 69.5 38.2 Yes Yes
2 empty 2.36 65.7 42.3 No No
3 empty 1.94 73.6 15.9 No No
4 empty 2.1 66.5 17.6 No No
5 empty 1.97 62.7 17.7 No No
6 empty 2.41 63.6 15.8 No No
7 empty 2.05 78.5 8.6 No No
8 empty 2.61 63 11.1 No No
9 empty 2.01 64.6 9.9 No No
10 empty 2.17 50.2 11.6 No No
5I09_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.48 80.4 21.1 Yes Yes
2 bound 2.11 66.1 41.6 No No
3 empty 2.29 66.2 23.6 No No
4 bound 1.85 75.3 12.3 No No
5 empty 2.12 59.3 15.9 No No
6 empty 2.02 61.8 16.2 No No
7 empty 2.08 59.2 19.1 No No
8 bound 2.41 59.1 15.9 No No
9 empty 2.39 70.7 8.7 No No
10 empty 1.99 78.6 8.3 No No
4PUN_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.64 75.2 42.6 Yes Yes
2 empty 2.22 66.6 41.5 No No
3 empty 2.22 63.8 17.4 No No
4 empty 1.78 76.2 13 No No
5 empty 2.25 64.6 16.7 No No
6 empty 2.18 60.7 23.4 No No
7 bound 2.39 59.6 16.4 No No
8 empty 1.88 75.4 8.6 No No
9 empty 2 79.2 9.9 No No
10 empty 2.05 62.4 8.8 No No
3HFY_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.54 69.8 53 Yes Yes
2 empty 1.98 68.7 16.5 No No
3 empty 1.87 74.4 12 No No
4 empty 2.05 68.1 12.4 No No
5 empty 2.36 60.3 18.6 No No
6 empty 2.04 79.1 7.4 No No
7 empty 2.34 70.8 7 No No
8 empty 1.79 64.1 13.9 No No
9 empty 1.98 65.7 13.1 No No
10 empty 1.85 67.7 8.3 No No
4HQV_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.52 73.3 45.6 Yes Yes
2 empty 2.22 63.2 33.1 No No
3 empty 2.03 75.7 14.4 No No
4 empty 2.26 64.5 17 No No
5 empty 2.15 61.6 17.1 No No
6 bound 1.99 70.2 12.2 No No
7 bound 2.43 59.9 15.7 No No
8 empty 2.24 67.1 8.5 No No
9 empty 1.97 77 7.6 No No
10 empty 1.91 63.2 9.7 No No
5JSV_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 80.5 20.7 Yes Yes
2 bound 2.2 66.6 41.3 No No
3 empty 2.46 65 20.5 No No
4 empty 1.87 75.2 14 No No
5 empty 1.97 70.4 13.6 No No
6 empty 2.02 60.9 15.9 No No
7 empty 2.22 60 15.3 No No
8 bound 2.34 62 15.7 No No
9 empty 2.06 58 16.3 No No
10 empty 1.98 78.2 10.6 No No
2Z1X_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 78.1 17.7 Yes No
2 empty 1.86 61.7 29.4 No No
3 bound 2.01 70.8 21.8 No No
4 empty 2.11 65.7 22.1 No No
5 bound 1.94 75.6 11.5 No No
6 empty 2.23 65.2 15.2 No No
7 bound 2.28 56.1 15.4 No No
8 empty 2.06 54.3 15.9 No No
9 empty 2.18 77.5 8.7 No No
10 bound 2.85 68.7 10 No No
4Q8P_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.57 79.7 25.5 Yes Yes
2 empty 1.62 62.5 26 No No
3 empty 2.49 65.6 25 No No
4 empty 2.04 75.7 15.2 No No
5 bound 2.28 72.4 20.3 No No
6 empty 2.43 64 17.4 No No
7 empty 2.4 59.3 12 No No
8 empty 2.09 73.4 12.5 No No
9 bound 2.29 58.2 15.6 No No
10 empty 2.04 55.1 15.3 No No
4GD0_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.56 78.7 27.8 Yes Yes
2 empty 2.1 65.2 34.4 No No
3 empty 1.98 74.6 12.9 No No
4 empty 2.27 66.8 16.2 No No
5 empty 2.21 65.2 17.6 No No
6 bound 2.13 71.8 16.7 No No
7 empty 2.06 62.7 16 No No
8 empty 1.63 64.6 11.9 No No
9 empty 2.18 56.6 15.1 No No
10 bound 2.4 60.8 15.7 No No
1N2V_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.73 72.6 42.3 Yes Yes
2 empty 2.22 66.3 27.5 No No
3 empty 1.97 74.2 17.6 No No
4 empty 2.33 65.5 18.8 No No
5 empty 2.16 71.9 16.3 No No
6 empty 2.03 61.7 18.4 No No
7 empty 2.21 66.6 14.3 No No
8 empty 2.38 60 15.6 No No
9 empty 1.92 60.4 17.8 No No
10 empty 2.56 76.2 11 No No
4Q4R_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 74 35 Yes Yes
2 bound 2.15 73.3 23.3 No No
3 empty 1.7 59.3 22.5 No No
4 empty 1.98 62.5 24.9 No No
5 empty 2.01 76.2 13.4 No No
6 empty 2.16 63.3 15.7 No No
7 bound 2.32 59 15.6 No No
8 empty 2.01 76.7 8.6 No No
9 empty 2.47 69.5 13.5 No No
10 bound 1.69 60 11.4 No No
3RR4_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.6 70.5 50.9 Yes Yes
2 empty 2.19 70 20.7 No No
3 empty 1.66 60.6 21.2 No No
4 empty 1.91 74.4 12.9 No No
5 empty 2.07 61.2 18.2 No No
6 empty 2.08 76.1 8.3 No No
7 empty 2.38 70.9 8 No No
8 empty 1.98 62.8 8.7 No No
9 empty 2.09 75.3 6.3 No No
10 empty 2.75 65 9.4 No No
4Q8Q_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 65.6 45 Yes No
2 bound 1.69 78.4 18.4 Yes No
3 empty 2.32 72.4 27.8 No No
4 empty 2.07 73 17.7 No No
5 empty 1.61 59.9 21.3 No No
6 empty 2.09 66.3 25.4 No No
7 empty 2.12 61.6 18.8 No No
8 empty 2.21 63.6 11.6 No No
9 empty 2.11 56.9 14 No No
10 empty 1.92 78.3 6.9 No No
2POT_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.69 72.1 35.3 Yes No
2 empty 1.82 61.6 28.7 No No
3 bound 2.1 72.1 22 No No
4 bound 1.9 71.8 13.7 No No
5 empty 2.08 61.4 15.5 No No
6 bound 2.24 67.3 17 No No
7 empty 2.09 54.3 16.4 No No
8 empty 2.02 80.6 8.1 No No
9 bound 2.05 71.8 6.8 No No
10 empty 1.93 77.4 10.2 No No
1Y5X_D Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.82 70.8 42.3 Yes Yes
2 empty 1.95 77.1 15.1 No No
3 empty 2.15 72.9 15.5 No No
4 empty 1.9 67.8 11.3 No No
5 empty 2.15 56.1 15 No No
6 empty 2.08 69.1 8 No No
7 empty 1.97 79.7 7.7 No No
8 empty 1.85 69.6 9.6 No No
9 empty 2.59 79.6 8.8 No No
10 empty 2.25 66.2 7.2 No No
4Q4O_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 71.3 46.7 Yes Yes
2 bound 2.16 71.1 22.8 No No
3 empty 1.64 60.7 21.8 No No
4 empty 2.06 67.5 24.4 No No
5 empty 1.96 75.4 15 No No
6 empty 2.05 60.3 16.2 No No
7 empty 2.19 63.7 13 No No
8 bound 2.38 57.4 15.6 No No
9 empty 2.03 77.6 8.4 No No
10 empty 2.44 68.6 13.5 No No
1Q66_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.42 75 27.4 Yes No
2 empty 2.29 65.8 42 No No
3 empty 1.98 74.1 17.4 No No
4 empty 2.33 67.1 17.1 No No
5 empty 2.2 64.9 18.6 No No
6 empty 2.13 61.6 16.3 No No
7 empty 2.25 61.5 15.8 No No
8 empty 2.37 64.1 14.1 No No
9 empty 2.36 58.3 12.9 No No
10 empty 1.99 80.3 7.2 No No
5LPS_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.78 74.6 29.5 Yes No
2 empty 2.01 68 19 No No
3 empty 2.16 65.1 22.1 No No
4 empty 1.79 66.7 18.5 No No
5 empty 1.96 75.7 12.9 No No
6 empty 1.98 63.2 18.5 No No
7 empty 2.11 55.8 15.7 No No
8 empty 1.87 67.6 15.5 No No
9 empty 2 57.9 15.1 No No
10 empty 1.8 68.3 9 No No
1OZM_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.51 74.2 37.7 Yes Yes
2 empty 2.47 64.9 42.2 No No
3 empty 2.01 75.2 12.9 No No
4 empty 2.11 62.4 18.2 No No
5 empty 2.08 60.8 17.6 No No
6 empty 2.22 59.4 15.6 No No
7 empty 2.26 57.6 15.6 No No
8 empty 2.1 57.7 17.3 No No
9 empty 2.21 64 9.6 No No
10 empty 1.95 76.3 9 No No
1Y5W_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.69 76 18.9 Yes No
2 empty 2.16 67.7 20.4 No No
3 bound 2.06 69.2 23.7 No No
4 empty 1.83 64.6 13.6 No No
5 empty 1.49 54.9 14.4 No No
6 empty 2.01 62.7 10.4 No No
7 empty 2.21 54.8 15.4 No No
8 empty 2.07 46.3 11.3 No No
9 bound 2.29 62.4 9.3 No No
10 empty 1.81 67.2 10.1 No No
3TLL_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 65.7 41.5 Yes No
2 bound 1.73 75.8 31.3 Yes No
3 empty 2.14 66.5 24.9 No No
4 empty 1.92 74.8 14 No No
5 empty 2.1 61.8 16.3 No No
6 empty 2.24 60.7 10.1 No No
7 empty 2.23 54.1 12.4 No No
8 empty 2.07 79.5 8.5 No No
9 empty 2.92 67.8 9 No No
10 empty 2.21 71 8.1 No No
4GIY_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 72.2 32.1 Yes No
2 empty 2.14 67.8 24 No No
3 empty 1.9 74.2 13.7 No No
4 empty 1.75 70.3 16.5 No No
5 empty 1.83 67.8 11.7 No No
6 empty 1.9 57.8 17.3 No No
7 empty 2.41 74 8.7 No No
8 empty 1.83 78 7 No No
9 empty 2.48 71.7 7.7 No No
10 empty 1.88 69.1 8.3 No No
5JSW_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 71.7 40 Yes Yes
2 bound 2.12 67.5 41.5 No No
3 bound 1.78 77.5 13.3 No No
4 empty 2.1 58.1 18.6 No No
5 empty 2.16 64.8 17.6 No No
6 empty 2.33 54.8 18 No No
7 bound 2.35 58.9 15.8 No No
8 empty 1.9 79.1 7.6 No No
9 empty 2.17 63.8 9.3 No No
10 empty 2.25 73.2 6.2 No No
2BBF_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.5 75.7 29.6 Yes Yes
2 empty 2.34 67.5 36.7 No No
3 empty 1.95 76.5 12.3 No No
4 empty 2.45 62.1 19.5 No No
5 empty 2.33 64.8 17.2 No No
6 empty 2.18 60.6 20.6 No No
7 empty 2.11 61.1 17.5 No No
8 empty 2.28 62.9 15.2 No No
9 empty 1.8 68.2 11.6 No No
10 empty 2.4 62 15.8 No No
4LBU_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 72.6 27 Yes Yes
2 empty 2.03 69.5 16.6 No No
3 empty 2.09 67 15.2 No No
4 empty 1.62 61.7 12.7 No No
5 empty 1.98 60.8 17.5 No No
6 empty 2.05 54.1 14.1 No No
7 bound 1.88 68.5 12.9 No No
8 empty 2.08 55.3 14.6 No No
9 empty 1.39 51.4 11.8 No No
10 empty 2 46.3 12.2 No No
1Q2S_B Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 70.3 53.6 Yes Yes
2 empty 2.24 64.4 26 No No
3 empty 2.12 63.6 16.4 No No
4 empty 2.28 65 19.7 No No
5 empty 2.29 56.1 18.9 No No
6 empty 2.15 59.4 15.8 No No
7 empty 1.78 66.8 12.1 No No
8 empty 2.42 64.8 15.5 No No
9 empty 2.28 60.7 10.4 No No
10 empty 2.42 68.2 7.7 No No
2PWV_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 66 41.6 Yes No
2 bound 1.83 72.1 33.9 No No
3 empty 2.36 69.6 25.2 No No
4 bound 1.98 75.4 12.9 No No
5 empty 2.27 60.8 19.4 No No
6 empty 2.18 61.9 13 No No
7 bound 2.31 59.2 16.4 No No
8 empty 2.46 53.2 18.9 No No
9 empty 1.95 77 8 No No
10 empty 2.04 76.5 6.4 No No
3GC5_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 68.1 51 Yes Yes
2 bound 2.09 66.5 39.7 No No
3 empty 2.39 68.1 25 No No
4 empty 2.01 75.3 17 No No
5 empty 2.21 62.7 17.8 No No
6 bound 2.38 60.4 16 No No
7 empty 2 79.5 7.2 No No
8 empty 1.7 71.6 9.1 No No
9 empty 2.11 71.3 6.2 No No
10 empty 2.11 65.9 9.6 No No
4HTB_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.57 73.7 37.8 Yes Yes
2 empty 2.06 65.9 40.8 No No
3 empty 1.78 75.8 15.4 No No
4 empty 2.33 65.3 19.3 No No
5 empty 2.39 64 18.7 No No
6 empty 2.2 61.4 16 No No
7 empty 2.25 57.3 11.8 No No
8 empty 2.31 66.8 12.7 No No
9 bound 2.45 70.8 7.6 No No
10 empty 1.95 77.9 8 No No
4FR1_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.54 74.7 23.7 Yes No
2 empty 2.08 68.5 23.3 No No
3 empty 1.46 57.2 19.2 No No
4 empty 1.96 74.5 12.2 No No
5 empty 2.18 75.3 11.4 No No
6 empty 2.47 65.5 12.9 No No
7 empty 2.33 73.2 9.6 No No
8 empty 2.18 55.5 13.7 No No
9 empty 2.3 60.1 11.1 No No
10 empty 2.42 75 7.4 No No
4DXX_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 76.7 24.8 Yes No
2 empty 1.84 70.6 15.4 No No
3 bound 2.01 67.2 16.6 No No
4 empty 1.71 59.2 14.5 No No
5 empty 1.63 57.1 17.6 No No
6 empty 1.98 53.7 16.9 No No
7 empty 1.98 69.2 12.8 No No
8 empty 1.98 62.8 15.4 No No
9 empty 1.96 51.8 11.4 No No
10 bound 2.3 57.5 14.1 No No
4PUM_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 67.9 29.1 Yes No
2 bound 2.14 67.1 24.8 No No
3 empty 1.89 68.4 24.8 No No
4 empty 1.86 72.3 12.7 No No
5 empty 1.79 64.3 13.9 No No
6 empty 2.11 53.2 18.6 No No
7 empty 2.28 66.8 11.6 No No
8 empty 1.45 56.4 10.9 No No
9 bound 2.26 61 9.3 No No
10 empty 2.49 66.5 9.8 No No
1S38_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 73.8 34.2 Yes Yes
2 empty 2.17 66.5 25.8 No No
3 empty 2.23 62.7 26.6 No No
4 empty 2.39 65.7 17.3 No No
5 empty 2.01 74.3 12.8 No No
6 empty 2.19 68.6 15.5 No No
7 empty 2.17 59.6 20.8 No No
8 empty 2.03 62.1 17.6 No No
9 empty 2.37 61.2 15.8 No No
10 empty 1.98 79.1 7.7 No No
5LPT_B Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.86 68 35 Yes Yes
2 empty 1.56 60.5 25.9 No No
3 empty 2.06 53.8 20.4 No No
4 empty 1.76 72.3 13.9 No No
5 bound 2.06 72.6 12.7 No No
6 empty 2.23 62.5 15 No No
7 empty 2.07 63 10.9 No No
8 empty 2 75.4 7.8 No No
9 empty 2.33 59.4 9.9 No No
10 empty 2.2 71.6 7.9 No No
4GHR_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.52 78.8 20.3 Yes Yes
2 empty 2.17 63.8 34.2 No No
3 empty 2.12 67.7 21.9 No No
4 empty 2.06 64.5 12 No No
5 empty 1.93 73.5 14 No No
6 empty 2.18 71.1 14 No No
7 bound 2.4 63.2 16.6 No No
8 empty 1.74 64.4 13.6 No No
9 empty 1.93 78.1 8.2 No No
10 empty 2.24 72 8.7 No No
4IPP_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.51 74.5 32.4 Yes No
2 empty 2.04 64.9 33.1 No No
3 empty 1.89 75.1 13.3 No No
4 empty 1.82 69.2 19 No No
5 empty 2.37 65.7 17.3 No No
6 empty 1.99 60 17.1 No No
7 bound 2.09 71.4 13 No No
8 empty 2.07 59 13.8 No No
9 bound 2.37 60.1 15.7 No No
10 empty 2.24 64.6 9.4 No No
3GC4_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.98 75.5 33.6 Yes No
2 empty 2.03 65.8 34.2 No No
3 empty 1.86 75.6 12.8 No No
4 empty 2.13 64 18.6 No No
5 empty 2.26 65.9 15.7 No No
6 empty 2.09 72.1 10.5 No No
7 bound 2.17 56.3 13.9 No No
8 empty 1.9 78.7 8.5 No No
9 bound 2.24 77 6.3 No No
10 empty 1.7 55.9 9.5 No No
4GH3_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.5 78.4 20.3 Yes No
2 empty 1.92 66.4 23.3 No No
3 empty 1.62 59.2 21.7 No No
4 empty 2.03 68.2 25.6 No No
5 empty 1.91 76 13.4 No No
6 empty 1.75 67.1 11 No No
7 empty 1.91 67.1 10.8 No No
8 empty 1.76 86.8 14.4 Yes No
9 empty 2.4 58.3 15.7 No No
10 empty 2.16 53 12.4 No No
3S1G_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.94 80.5 23 Yes Yes
2 empty 2.16 70 24.9 No No
3 empty 2.14 64.6 21.8 No No
4 empty 1.72 62.1 22.8 No No
5 empty 1.87 75.2 12.8 No No
6 empty 1.97 63.4 15.5 No No
7 bound 2.43 59.8 16.3 No No
8 empty 2.09 57 14.6 No No
9 empty 2.07 66.8 11.7 No No
10 empty 1.83 78.8 8.6 No No
4GCX_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2 70.9 45.7 Yes Yes
2 bound 2.1 64.3 41.6 No No
3 empty 1.95 73.8 12.8 No No
4 empty 2.21 61.5 19.5 No No
5 empty 2.27 62.1 19.3 No No
6 bound 2.37 60.9 15.7 No No
7 empty 1.56 68.3 10.7 No No
8 empty 2.35 70.2 8.4 No No
9 empty 1.95 80.6 7.9 No No
10 empty 1.95 57.9 11.4 No No
1Q2R_B Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 83.4 25.1 Yes Yes
2 empty 2.07 65.9 42.5 No No
3 empty 1.93 70.7 17.2 No No
4 empty 2.4 70.5 20.1 No No
5 empty 2.33 62.4 18.4 No No
6 empty 1.98 62.5 15.7 No No
7 empty 2.14 57.3 13.7 No No
8 empty 2.46 44 19.4 No No
9 empty 2.38 65.7 10.2 No No
10 empty 2.07 79.7 8.1 No No
5LPQ_B Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.56 68.9 44.2 Yes Yes
2 empty 2.43 58 22.9 No No
3 empty 1.86 69.6 15 No No
4 empty 2.25 63.4 20.1 No No
5 empty 2.16 73.9 8.4 No No
6 empty 1.45 64.6 10.8 No No
7 empty 1.92 58 14.6 No No
8 empty 2.05 68.6 9.4 No No
9 empty 2.65 71.8 8 No No
10 empty 1.9 71.3 8.2 No No
4Q4P_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.9 72.3 37.3 Yes Yes
2 empty 1.94 62.4 27.3 No No
3 empty 2.15 71.9 23.3 No No
4 empty 1.99 68.6 25.1 No No
5 empty 2.1 75.9 15.4 No No
6 empty 2.1 64 16.2 No No
7 bound 2.35 58.6 15.6 No No
8 empty 2.06 76.4 8.3 No No
9 empty 1.96 66.1 8.3 No No
10 empty 1.98 65.6 8.8 No No
1WKF_A Queuine tRNA-ribosyltransferase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.8 77.5 32.9 Yes No
2 empty 1.94 60.3 28.4 No No
3 empty 2.49 66.9 20.3 No No
4 empty 2.01 75.8 14.3 No No
5 empty 2.38 70.7 23.9 No No
6 empty 2.1 62.7 17.6 No No
7 empty 2.32 60.2 16.1 No No
8 empty 2.26 61.2 15.3 No No
9 empty 2.38 59.9 15.9 No No
10 empty 1.95 77 9.4 No No
5JT6_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.88 74.7 29.3 Yes Yes
2 bound 2.16 65.9 23.8 No No
3 empty 1.99 55.2 17.6 No No
4 empty 1.67 66.4 12.3 No No
5 empty 1.77 63.2 14.3 No No
6 empty 2.63 68.7 10.3 No No
7 empty 2.02 50.2 13 No No
8 empty 1.46 50.5 11.5 No No
9 empty 1.55 95.1 0 Yes No
10 empty 2.03 43.3 9.9 No No
6FPU_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.77 72.1 42.7 Yes Yes
2 empty 2.32 66.5 23.4 No No
3 bound 2.23 71.4 23.2 No No
4 empty 1.64 60 22 No No
5 empty 1.92 75.6 12.8 No No
6 empty 2.3 59.7 16.8 No No
7 bound 2.32 55.7 15.6 No No
8 empty 2.29 62 12.5 No No
9 empty 2.03 77.9 8.2 No No
10 empty 2.04 74.4 6.8 No No
2QII_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.97 76.5 34.2 Yes Yes
2 bound 2.35 66.2 41.9 No No
3 empty 2.42 68.9 24.4 No No
4 empty 1.99 75.6 14.3 No No
5 empty 2.09 59 16.8 No No
6 empty 2.45 62.2 12.1 No No
7 empty 2.35 63.7 10 No No
8 bound 2.31 65 9 No No
9 empty 2.39 69.2 8 No No
10 empty 1.97 77.7 7.9 No No
5I07_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.8 68.8 40.2 Yes Yes
2 empty 2.03 59.1 21.7 No No
3 bound 2.08 70.8 16 No No
4 empty 1.9 74.7 13.8 No No
5 empty 2.2 61.7 9.4 No No
6 empty 1.34 69.3 7.7 No No
7 empty 2.12 53.6 14.9 No No
8 empty 2.05 77 8.2 No No
9 empty 2.6 67.3 14.9 No No
10 empty 2.16 66.5 7.4 No No
1Q2R_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.03 75.4 35.8 Yes Yes
2 empty 2.31 71.3 21.9 No No
3 empty 2.01 58.9 27.8 No No
4 empty 1.94 70.7 15.6 No No
5 empty 2.58 64.5 24.4 No No
6 empty 2.77 65.7 17 No No
7 empty 2.42 57.8 16.3 No No
8 empty 2.42 57.4 16.6 No No
9 empty 2.65 68.9 9.9 No No
10 empty 2.13 58.2 15.3 No No
4H6E_A Queuine tRNA-ribosyltransferase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.5 72.6 41 Yes Yes
2 empty 2.01 61.8 24.8 No No
3 bound 2.1 74 14 No No
4 bound 2.4 71.3 21.4 No No
5 empty 2.01 61.9 18.2 No No
6 empty 1.99 57.5 14.2 No No
7 bound 2.45 62.7 15.8 No No
8 empty 2.52 68.7 8.7 No No
9 empty 2.26 64 9.1 No No
10 empty 1.99 78 7.7 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed62
Domains assessed as druggable using the strict criteria40
Domains assessed as druggable using the relaxed criteria62

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1EFZ_A (29659) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2Å Yes Yes
1ENU_A (29660) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.95Å Yes Yes
1F3E_A (29661) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.85Å Yes Yes
1K4G_A (72054) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.7Å Yes Yes
1K4H_A (72055) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.8Å Yes Yes
1N2V_A (85288) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.1Å Yes Yes
1OZM_A (93850) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.95Å Yes Yes
1OZQ_A (93854) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.9Å Yes Yes
1P0B_A (93863) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.7Å Yes Yes
1P0D_A (93864) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.9Å Yes Yes
1P0E_A (93865) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.4Å Yes Yes
1PUD_A (29658) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.85Å Yes No
1PXG_A (95287) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.7Å Yes No
1Q2R_D (95637) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.9Å Yes Yes
1Q2R_C (95636) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.9Å Yes No
1Q2R_A (95634) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.9Å Yes Yes
1Q2R_B (95635) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.9Å Yes Yes
1Q2S_B (95639) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 3.2Å Yes Yes
1Q2S_C (95640) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 3.2Å Yes Yes
1Q2S_D (95641) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 3.2Å Yes Yes
1Q2S_A (95638) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 3.2Å Yes Yes
1Q4W_A (95832) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.93Å Yes Yes
1Q63_A (95957) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.85Å Yes No
1Q65_A (95958) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.1Å Yes Yes
1Q66_A (95959) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.75Å Yes No
1R5Y_A (97134) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.2Å Yes Yes
1S38_A (105234) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.8Å Yes Yes
1S39_A (112010) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.95Å Yes Yes
1WKD_A (29664) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.6Å Yes Yes
1WKE_A (29663) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.2Å Yes Yes
1WKF_A (29662) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.2Å Yes No
1Y5V_A (122653) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.58Å Yes No
1Y5W_A (122654) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.58Å Yes No
1Y5X_A (122655) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.1Å Yes Yes
1Y5X_D (122656) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2.1Å Yes Yes
2BBF_A (128265) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.7Å Yes Yes
2NQZ_A (3150603) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.46Å Yes Yes
2NSO_A (3150650) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.6Å Yes Yes
2OKO_A (3160747) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.5Å Yes Yes
2POT_A (3180041) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.8Å Yes No
2PWU_A (149904) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.77Å Yes Yes
2PWV_A (3180294) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.7Å Yes No
2QII_A (150810) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.7Å Yes Yes
2QZR_A (151491) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.95Å Yes No
2Z1V_A (3280343) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.55Å Yes Yes
2Z1W_A (3280344) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.63Å Yes Yes
2Z1X_A (3280345) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.63Å Yes No
2Z7K_A (154198) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.28Å Yes Yes
3BL3_A (3320277) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 2.25Å Yes No
3BLD_A (3320285) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.19Å Yes No
3BLL_A (3320298) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.26Å Yes No
3BLO_A (3320302) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.6Å Yes No
3C2N_A (3330183) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.58Å Yes No
3C2Y_A (3330206) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.78Å Yes Yes
3C2Z_A (3330207) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.65Å Yes No
3EOS_A (4192453) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.78Å Yes No
3EOU_A (4161577) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 1.93Å Yes No
3GC4_A (3430233) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.8Å Yes No
3GC5_A (3430234) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.4Å Yes Yes
3GE7_A (3430367) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.5Å Yes Yes
3GEV_A (3430406) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, UNMATCHED 1.53Å Yes No
3HFY_A (4169462) Queuine tRNA-ribosyltransferase TIM beta/alpha-barrel, tRNA-guanine transglycosylase, tRNA-guanine transglycosylase 2Å Yes Yes
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score