Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ERCC5 (P28715) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0Z_B 48.94 1.0E-24 2.4Å - 2014-08-27
XPG I-region (100%) (view alignment) fen (O50123) - 1MC8_B 35.17 8.0E-13 3Å - 2002-10-16
XPG I-region (100%) (view alignment) GEN1 (Q17RS7) - HUMAN 5T9J_B 40.62 2.0E-21 3Å - 2016-09-21
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0W_B 48.94 1.0E-24 2.1Å - 2014-08-27
(view alignment) ERCC5 (P28715) Kpna2 (P52293) HUMAN 5EKF_B 100 0 1.964Å - 2016-02-10
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0Z_E 48.94 1.0E-24 2.4Å - 2014-08-27
XPG I-region (100%) (view alignment) GEN1 (Q17RS7) - HUMAN 5T9J_A 40.62 2.0E-21 3Å - 2016-09-21
XPG I-region (100%) (view alignment) fen (O50123) - 1MC8_A 35.17 8.0E-13 3Å - 2002-10-16
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0Z_A 48.94 1.0E-24 2.4Å - 2014-08-27
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q10_A 48.94 1.0E-24 2.7Å - 2014-08-27
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q10_B 48.94 1.0E-24 2.7Å - 2014-08-27
(view alignment) ERCC5 (P28715) Kpna2 (P52293) 5EKG_B 100 0 2.8Å - 2016-02-10
XPG I-region (100%) (view alignment) fen (O93634) - 1B43_B 36.55 4.0E-14 2Å - 2000-01-12
(view alignment) ERCC5 (P28715) Kpna2 (P52293) 5EKG_C 100 0 2.8Å - 2016-02-10
XPG I-region (100%) (view alignment) fen (O93634) - 1B43_A 36.55 4.0E-14 2Å - 2000-01-12
XPG N-terminal domain (97%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0R_B 49.47 3.0E-25 2.75Å - 2014-08-27
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0W_A 48.94 1.0E-24 2.1Å - 2014-08-27
XPG N-terminal domain (96%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0Z_F 48.94 1.0E-24 2.4Å - 2014-08-27
XPG N-terminal domain (97%), XPG I-region (100%) (view alignment) RAD2 (P07276) - BAKER'S YEAST 4Q0R_A 49.47 3.0E-25 2.75Å - 2014-08-27
(view alignment) ERCC5 (P28715) Kpna2 (P52293) HUMAN 5EKF_C 100 0 1.964Å - 2016-02-10