Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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Germline Genetics

Defa4 (P28311) - Overview - Molecular Target Synopsis

Protein


Defa4, Alpha-defensin 4
UniProt P28311

Also Known as DEFA4_MOUSE, Defa4, Defcr4

Probably contributes to the antimicrobial barrier function of the small bowel mucosa.

2LEY
SOLUTION STRUCTURE OF (R7G)-CRP4
RCSB/PDB
Inspect Structure
See all 3D Structures for Defa4

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
92P28311-1

Sub-cellular localization


UniProt: Defa4 is active in the following subcellular-locations: secreted.
GO terms: Defa4 is active in the following subcellular-locations: extracellular space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project Defa4 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For Defa4 there are:
5 structures (5 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis