Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

cynR (P27111) - Overview - Molecular Target Synopsis

Protein


cynR, HTH-type transcriptional regulator CynR
UniProt P27111

Also Known as CYNR_ECOLI, cynR

Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region.

3HFU
CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF E. COLI CYNR WITH ITS SPECIFIC EFFECTOR AZIDE
RCSB/PDB
Inspect Structure
See all 3D Structures for cynR

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
299P27111-1

Sub-cellular localization


UniProt: cynR is active in the following subcellular-locations: cytoplasm.
GO terms: cynR is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project cynR has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For cynR there are:
2 structures (6 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis