Molecular Target Synopsis
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LTF (P24627) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/07/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 23/07/2019)


Chains assessed79
Chains with at least one site assessed as druggable using the strict criteria21
Chains with at least one site assessed as druggable using the relaxed criteria79


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
5CRY_B Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 64.7 38.9 Yes No
2 bound 2.24 64.4 32.8 No No
3 bound 2.02 66.9 33.2 No No
4 empty 2.43 70.4 21.5 No No
5 empty 2.03 60.7 22.7 No No
6 empty 2.13 61 19.2 No No
7 empty 2.26 65.7 15.8 No No
8 empty 2.48 66.9 15.6 No No
9 empty 2.13 65.5 11.1 No No
10 empty 2.22 66.2 13.5 No No
1SDX_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 65.1 34.2 Yes No
2 empty 2.41 66.9 24.7 No No
3 bound 2.03 66 34.5 No No
4 empty 2.14 64 21.2 No No
5 empty 1.94 70.2 14.5 No No
6 empty 2.15 64.7 19.4 No No
7 empty 1.84 60.9 16.4 No No
8 empty 1.72 94.4 9.1 Yes No
9 empty 1.89 56 13.3 No No
10 empty 1.95 71 10.1 No No
2O51_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.5 65 47.2 Yes No
2 empty 1.83 63.8 28.1 No No
3 empty 2.15 62.8 22 No No
4 empty 2.04 60.9 15.6 No No
5 bound 2.02 71.2 11.8 No No
6 empty 1.78 94.1 8.9 Yes No
7 empty 2.2 68 13.1 No No
8 bound 2.03 60.4 14.5 No No
9 empty 2.38 59 9.2 No No
10 empty 2.04 68.4 9.8 No No
3TAJ_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.16 69.2 38.5 Yes Yes
2 empty 1.95 68.6 19.5 No No
3 empty 2.33 61.2 27.7 No No
4 empty 2.12 68.4 23.8 No No
5 empty 2.17 62.7 21.8 No No
6 bound 1.95 73.9 13.7 No No
7 bound 1.96 67.2 13.9 No No
8 empty 1.76 92.5 0 Yes No
9 empty 2.43 55.3 16 No No
10 empty 2.23 70.4 10.1 No No
2HCA_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.41 65 45.5 Yes No
2 empty 2.01 67 20.8 No No
3 empty 2.14 62.1 22.6 No No
4 empty 1.99 61.8 17 No No
5 bound 1.88 67.2 17.8 No No
6 empty 1.76 94.7 9 Yes No
7 empty 2.18 69.9 14.5 No No
8 empty 2.07 53.2 15.2 No No
9 bound 2.09 61.1 9.8 No No
10 empty 2.08 66.5 9.3 No No
5CRY_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.56 67.9 42.4 Yes Yes
2 empty 1.73 66.8 27.3 No No
3 empty 1.96 64.9 36.1 No No
4 empty 2.18 67.7 19 No No
5 empty 2.05 58.2 20.5 No No
6 empty 2.02 65.5 14.8 No No
7 empty 1.65 61 18.4 No No
8 empty 2.26 55.2 16.3 No No
9 empty 1.7 94.3 0 Yes No
10 empty 1.97 57.9 11.7 No No
4FOR_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.3 65.1 32.3 Yes No
2 bound 1.96 63.4 30.6 No No
3 empty 2.41 65.7 21.5 No No
4 empty 2.26 62.3 23.3 No No
5 empty 2.09 60 24.1 No No
6 empty 1.94 66 17.6 No No
7 empty 2.27 66.7 17.3 No No
8 empty 1.74 89.8 11.7 Yes No
9 empty 1.74 66.8 14.8 No No
10 bound 2.1 72.1 9.5 No No
3K0V_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 64.6 47.9 Yes No
2 empty 2.04 69.6 20.7 No No
3 empty 2.26 65.5 21.6 No No
4 bound 1.84 68.5 22.1 No No
5 empty 2.07 64.7 16.5 No No
6 empty 2.26 68.3 17.6 No No
7 bound 1.92 65 13.7 No No
8 empty 2.07 57.8 17.7 No No
9 empty 2.27 58.5 17.9 No No
10 empty 1.72 91.6 0 Yes No
2DSF_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 65.1 46.3 Yes No
2 empty 1.93 64.7 23.1 No No
3 empty 1.99 62.3 20.5 No No
4 empty 2.18 65 14.4 No No
5 empty 1.96 68.2 14.4 No No
6 bound 1.89 62 17.6 No No
7 empty 2.26 66.5 17.5 No No
8 empty 2.39 56.2 16.8 No No
9 empty 1.8 94 8.7 Yes No
10 empty 2.04 56.7 14.6 No No
4OQO_B Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 60.1 54.2 Yes No
2 empty 2.2 71 17.3 No No
3 empty 1.87 71.1 11.4 No No
4 empty 1.97 60.7 12.4 No No
5 bound 2.2 63.5 15.1 No No
6 empty 1.68 73.9 11.9 No No
7 empty 2.32 63.6 13.3 No No
8 empty 1.86 59.2 16 No No
9 empty 2.31 60 15.6 No No
10 empty 2.5 65.2 10.7 No No
3CRB_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 64.1 33.3 Yes No
2 empty 1.95 64.5 39.8 No No
3 bound 2 67.3 38.6 No No
4 empty 2.38 67.6 23.8 No No
5 empty 2.02 65 20.9 No No
6 empty 1.89 62.7 18.3 No No
7 empty 1.75 94.3 0 Yes No
8 empty 1.98 50.6 16.9 No No
9 empty 1.85 62.4 9.4 No No
10 empty 2.49 56.2 10 No No
4OQO_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 63.8 45.5 Yes No
2 empty 2.07 60.1 26.3 No No
3 empty 1.97 68.8 12.8 No No
4 bound 2.15 63.9 17.6 No No
5 empty 2.2 64.8 11 No No
6 empty 1.83 63.7 12.8 No No
7 empty 2.1 60.5 13.3 No No
8 empty 2.32 41 11 No No
9 empty 2.33 66.4 13.1 No No
10 empty 1.72 65.8 10.8 No No
3E9X_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 65.4 34.8 Yes No
2 empty 1.94 69.1 21.4 No No
3 empty 2.35 66.9 18.8 No No
4 empty 1.78 67.3 22.2 No No
5 empty 2.21 63.4 20.3 No No
6 empty 1.94 66.6 16.1 No No
7 empty 2.25 66.4 16.5 No No
8 empty 1.65 97.1 0 Yes No
9 bound 1.96 67.8 12.2 No No
10 empty 2.27 59 12.5 No No
2AYS_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 65.3 33.5 Yes No
2 empty 2.4 67.4 24.7 No No
3 empty 2.02 64.9 21.8 No No
4 empty 2.14 62.8 21.8 No No
5 bound 2.08 66.9 23.4 No No
6 empty 2.04 65.7 16.4 No No
7 bound 1.97 66.3 17.3 No No
8 empty 2.07 70 13.7 No No
9 empty 1.73 94.6 0 Yes No
10 empty 2.13 48.3 17.6 No No
2DWJ_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 63.5 32.7 Yes No
2 empty 2.4 64.7 24.3 No No
3 empty 1.88 67.5 19.5 No No
4 empty 2.15 65.9 21.3 No No
5 empty 2.12 65.2 20.4 No No
6 empty 2.13 64 16.7 No No
7 bound 2 71.2 15.9 No No
8 empty 1.75 91.2 10 Yes No
9 bound 2 68.1 12.6 No No
10 empty 1.85 66.1 11.5 No No
2H4I_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 65.3 33.5 Yes No
2 empty 2.36 67.8 19.8 No No
3 bound 1.96 67.9 26.2 No No
4 empty 2.18 60.2 20.6 No No
5 empty 2.24 67.4 16.5 No No
6 empty 1.99 71.5 13.1 No No
7 empty 2.01 66.4 14.2 No No
8 empty 1.75 94 0 Yes No
9 empty 2.04 57 16.2 No No
10 empty 1.78 64.3 14.4 No No
2NUV_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.37 64.2 43.7 Yes No
2 empty 1.98 63.6 31.7 No No
3 empty 2.08 65.8 18.4 No No
4 empty 2.07 64.9 16.3 No No
5 empty 2.26 68.8 17.2 No No
6 bound 2.04 68.5 13.3 No No
7 bound 1.99 65.2 15 No No
8 empty 2.17 51.9 14.9 No No
9 empty 1.75 90.1 10.2 Yes No
10 empty 2.22 50.2 12.6 No No
2DYX_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.98 63.9 33 Yes No
2 empty 1.97 64.4 33 No No
3 empty 2.36 67.2 24.2 No No
4 bound 1.95 66.3 33.5 No No
5 empty 2.17 65.4 19.8 No No
6 empty 2.25 67.9 17.3 No No
7 empty 1.97 63.7 16.3 No No
8 empty 1.76 94.4 9.2 Yes No
9 empty 2.21 53.4 14.2 No No
10 empty 1.86 66.4 9.5 No No
3IB2_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 65.2 35.2 Yes No
2 empty 2.39 68 23.5 No No
3 empty 1.99 71.1 21.3 No No
4 empty 2.14 63.1 23 No No
5 bound 2.04 67.8 22.8 No No
6 empty 1.96 66.7 16.2 No No
7 bound 2.06 64.5 15.2 No No
8 empty 2.19 71.9 13.3 No No
9 empty 1.71 95.5 9.1 Yes No
10 empty 2.34 54.9 16.7 No No
3O97_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.2 63.5 32.9 Yes No
2 empty 2.26 64.3 26 No No
3 empty 1.99 70.3 20.8 No No
4 empty 2.17 61.9 20.9 No No
5 empty 1.97 65 17 No No
6 bound 1.96 71.8 14.5 No No
7 empty 1.73 95.4 8.5 Yes No
8 empty 2.08 70.2 13.3 No No
9 bound 2.06 65.4 14.6 No No
10 empty 2.15 57.1 16.9 No No
2O1L_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 64 33.4 Yes No
2 empty 1.88 63.7 29 No No
3 empty 2.21 65 24.2 No No
4 bound 1.99 66.9 26.4 No No
5 empty 2.21 64.9 22.3 No No
6 empty 1.92 65 15.9 No No
7 bound 2.33 66.9 17.7 No No
8 empty 1.78 94.3 8.8 Yes No
9 empty 1.95 67.7 9.8 No No
10 empty 2.06 46.4 12.6 No No
2QJE_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 64 32.4 Yes No
2 empty 2.31 64.5 25.3 No No
3 empty 1.83 63.1 28.9 No No
4 empty 2.18 64.4 21 No No
5 empty 1.93 63 16.2 No No
6 bound 2.03 69.2 14.1 No No
7 bound 1.95 63.8 13.8 No No
8 empty 1.75 93.6 8.9 Yes No
9 empty 2.06 72.8 12.3 No No
10 empty 2.32 60.2 10.3 No No
2P1S_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.08 65.2 34 Yes No
2 empty 2.36 66.7 21.5 No No
3 bound 1.95 65.6 23.7 No No
4 empty 1.97 66.8 21.5 No No
5 empty 2.25 61.1 23.3 No No
6 empty 2.07 68.3 16.7 No No
7 empty 2.24 69.7 13.3 No No
8 empty 1.77 94 0 Yes No
9 empty 2.12 52.3 17.4 No No
10 empty 1.87 66.1 10.6 No No
4GRK_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.43 66.6 44.9 Yes Yes
2 bound 1.91 64.5 31.8 No No
3 empty 2.13 63.1 21.7 No No
4 empty 1.95 64.6 16.2 No No
5 empty 2.27 68.9 17 No No
6 empty 1.83 59.4 16.3 No No
7 empty 1.71 93.1 8.9 Yes No
8 empty 1.86 67.9 15.3 No No
9 empty 2.32 58.8 9.9 No No
10 bound 2.49 63.7 11.6 No No
3VDF_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.1 68.8 31.5 Yes Yes
2 empty 2.33 66.8 27.4 No No
3 bound 1.9 64.7 30.3 No No
4 empty 2.28 62 23.2 No No
5 empty 2.16 56.4 24 No No
6 empty 2.26 67.4 16.6 No No
7 empty 1.78 93.8 11.7 Yes No
8 empty 1.76 67.5 14.8 No No
9 empty 2.04 69 9 No No
10 empty 2.4 51.3 10.8 No No
3MJN_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.84 63.5 33.3 Yes No
2 empty 2.38 65.7 24.7 No No
3 empty 1.87 67.4 22.9 No No
4 empty 2.08 65.4 20.2 No No
5 bound 2.07 67.6 21.1 No No
6 empty 1.92 68.2 15.1 No No
7 empty 2.26 67.4 15.9 No No
8 bound 1.97 64.9 15.7 No No
9 empty 1.71 95.1 0 Yes No
10 empty 2.12 54.3 16.7 No No
5HBC_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.51 67.6 42.4 Yes Yes
2 empty 1.73 66.9 27.3 No No
3 empty 1.96 64.9 36.1 No No
4 empty 2.12 58.2 27.3 No No
5 empty 2.19 67.4 19 No No
6 empty 2.02 65.7 14.8 No No
7 empty 1.65 61.4 18.4 No No
8 empty 2.26 55.7 16.3 No No
9 empty 1.67 92.7 0 Yes No
10 empty 2.31 61.9 10.4 No No
3IB0_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.53 66.1 44.8 Yes Yes
2 bound 2 65.5 23.5 No No
3 empty 1.95 71.6 23.2 No No
4 empty 2.27 66.8 16.6 No No
5 empty 1.99 65.2 17.1 No No
6 empty 1.96 58.8 18.8 No No
7 empty 1.97 64 14.5 No No
8 empty 1.75 94.5 11.3 Yes No
9 bound 2.36 57.7 10.8 No No
10 empty 2.46 65.8 10.5 No No
2ALU_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 63.3 34.7 Yes No
2 empty 2.38 66.9 20.5 No No
3 bound 1.95 65.3 33.2 No No
4 empty 2.11 62.9 20.6 No No
5 empty 1.82 65.6 17.8 No No
6 empty 1.99 63.8 14.2 No No
7 empty 2.17 64.9 13.5 No No
8 empty 1.73 92.7 0 Yes No
9 empty 2.14 51.2 17.9 No No
10 empty 1.93 60.7 10.7 No No
3UK4_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.22 65 34.6 Yes No
2 bound 1.95 67.1 27.1 No No
3 empty 2.4 69.6 18.9 No No
4 empty 2.12 62.1 23.1 No No
5 empty 1.92 63.7 16.6 No No
6 empty 2.29 68.4 16.9 No No
7 empty 1.9 64.9 16.9 No No
8 empty 1.75 93.2 10.5 Yes No
9 empty 2.3 55.1 11 No No
10 empty 1.98 67 10.1 No No
3CI8_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.01 62.7 32.9 Yes No
2 empty 1.89 64.9 31.4 No No
3 empty 2.34 67.7 24.4 No No
4 bound 2.04 69.5 23.8 No No
5 empty 2.11 62.6 20.6 No No
6 empty 2.02 64.3 15.2 No No
7 empty 2.17 66.5 17.2 No No
8 empty 1.75 94.1 0 Yes No
9 empty 2.18 52.7 16.3 No No
10 empty 1.96 66.4 9.1 No No
4FIM_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.21 67.4 31.9 Yes Yes
2 bound 1.98 64.6 31.3 No No
3 empty 2.42 64.6 20.5 No No
4 empty 1.87 63.1 23.1 No No
5 empty 1.93 63.1 16.4 No No
6 empty 2.26 67.3 19 No No
7 empty 1.91 62.9 16.1 No No
8 empty 1.74 93.3 11.7 Yes No
9 empty 1.98 67.9 13.7 No No
10 empty 2.37 59.1 10.9 No No
3TOD_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.5 68.7 42.4 Yes Yes
2 bound 2.01 65.7 28.5 No No
3 empty 2.13 59.9 21.5 No No
4 empty 2.31 65.9 16.7 No No
5 empty 1.89 58.8 23.9 No No
6 bound 1.93 64 17.3 No No
7 bound 1.74 92 12.2 Yes No
8 empty 2.56 59.7 12 No No
9 empty 1.94 72.5 10.3 No No
10 empty 2.13 53.6 10.1 No No
4DIG_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 68.6 32.3 Yes Yes
2 bound 1.88 64.3 33.6 No No
3 empty 2.4 63.8 21.2 No No
4 empty 2.24 62.1 25.4 No No
5 empty 2 64 14.8 No No
6 empty 2.31 69 16.5 No No
7 empty 1.81 62.6 17.2 No No
8 empty 1.73 91.4 0 Yes No
9 empty 2.14 56.5 9.7 No No
10 empty 1.9 72.1 9.7 No No
3RGY_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 64.4 33.4 Yes No
2 empty 2 64.7 30 No No
3 empty 2.34 66.4 20.1 No No
4 empty 2.19 66.3 16.8 No No
5 empty 2.16 62.7 21.9 No No
6 bound 2.04 66.7 23 No No
7 empty 2.22 66.8 19.4 No No
8 bound 1.93 68.1 13.2 No No
9 empty 1.72 95.2 10.5 Yes No
10 empty 2.38 55.4 18.2 No No
3UGW_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.99 66.2 34.9 Yes Yes
2 bound 1.89 66.4 25.5 No No
3 empty 2.17 67.1 19.1 No No
4 empty 2.18 62.2 21.8 No No
5 bound 1.9 62.7 16.1 No No
6 empty 2.21 69 16.2 No No
7 empty 2.22 56.6 20.2 No No
8 empty 1.75 93.2 0 Yes No
9 empty 2.37 53.8 18.8 No No
10 empty 2.07 72.1 9.2 No No
2DWH_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 64.2 33 Yes No
2 empty 2.38 66.3 22.8 No No
3 empty 1.92 61.3 25.9 No No
4 bound 1.72 64.5 19.8 No No
5 empty 2.02 59.9 19.2 No No
6 bound 1.87 65.3 14.8 No No
7 empty 1.94 62.9 15.3 No No
8 empty 2.11 57.4 15 No No
9 empty 2.09 69.4 12.8 No No
10 empty 1.75 95.3 8.3 Yes No
3USD_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.45 68 42.1 Yes Yes
2 bound 1.93 65.3 25.4 No No
3 empty 2.06 63.5 16.8 No No
4 empty 2.23 64 17.7 No No
5 empty 2.12 64.6 17.9 No No
6 empty 1.83 57 17.3 No No
7 empty 1.69 94.2 9.1 Yes No
8 empty 1.69 62.4 16 No No
9 empty 2.35 57.3 13.5 No No
10 empty 2.26 47.7 12 No No
4FJP_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.14 68.8 32.2 Yes Yes
2 empty 2.49 65.6 27.7 No No
3 bound 1.93 64.2 26.3 No No
4 empty 2.33 61.3 24.5 No No
5 empty 2.07 59.5 25.5 No No
6 empty 2.26 65.4 19 No No
7 empty 1.79 92.9 11.7 Yes No
8 empty 1.91 67.3 14.9 No No
9 empty 2 69.4 9.4 No No
10 empty 2.38 60.3 9 No No
5HBC_B Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 64.9 38.9 Yes No
2 bound 2.25 64.5 32.8 No No
3 bound 2.02 66.5 33.4 No No
4 empty 2.44 70 21.5 No No
5 empty 2.02 60.4 22.7 No No
6 empty 2.22 61.9 20.8 No No
7 empty 2.26 65.7 15.8 No No
8 empty 2.48 65.7 15.1 No No
9 empty 2.14 65.2 11.1 No No
10 empty 2.22 66.2 13.5 No No
3U72_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 68.6 32.2 Yes Yes
2 bound 1.91 67.2 23.4 No No
3 empty 2.5 64.4 18.8 No No
4 empty 2.05 59.9 24.7 No No
5 empty 2.05 60.9 22.3 No No
6 empty 2.02 64.3 16.8 No No
7 empty 2.26 69.3 16.1 No No
8 empty 1.75 91.8 11.2 Yes No
9 empty 1.81 68.2 12.8 No No
10 empty 2.32 61.4 10.4 No No
3SDF_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.18 67.5 35 Yes Yes
2 empty 1.78 67.4 32.7 No No
3 empty 2.32 64 20.6 No No
4 empty 2.27 65.2 20.6 No No
5 bound 2.02 69.3 20.5 No No
6 empty 1.95 65.4 16.4 No No
7 empty 2.22 71.8 15.7 No No
8 bound 1.94 65.3 13.8 No No
9 empty 1.7 93.7 6.8 Yes No
10 empty 2.24 56.1 14.8 No No
2DVC_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 64.5 35.6 Yes No
2 empty 1.84 65.7 25.8 No No
3 empty 2.28 65.8 20.3 No No
4 empty 2.06 64 15.7 No No
5 empty 2.16 63.8 20.2 No No
6 bound 1.77 66.1 21.4 No No
7 empty 2.18 64.9 20.1 No No
8 empty 1.73 94.3 9.2 Yes No
9 bound 1.56 58.8 13.1 No No
10 empty 2.04 64.5 9.4 No No
4G77_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.24 66.3 32.7 Yes Yes
2 empty 2.45 67.2 26.9 No No
3 empty 1.94 65.9 27.5 No No
4 bound 2 65.9 27.7 No No
5 empty 2.21 60.4 23.5 No No
6 empty 2.23 67 16.2 No No
7 empty 1.77 91.3 11.7 Yes No
8 empty 1.92 68.9 14.7 No No
9 empty 2.22 60.5 15.1 No No
10 empty 2.38 59.2 10.3 No No
2ZMB_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 64 33.8 Yes No
2 empty 1.91 66.9 31 No No
3 empty 2.35 69.2 20.5 No No
4 bound 1.99 69.4 22.7 No No
5 empty 2.14 65.3 21.3 No No
6 empty 2.19 68.5 17 No No
7 empty 2.08 64.3 15.4 No No
8 empty 1.79 94.9 10.8 Yes No
9 empty 2.32 53 20.3 No No
10 empty 2.4 59.4 10.8 No No
3CFL_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.89 64.7 33.6 Yes No
2 empty 1.86 65.7 35.4 No No
3 empty 2.36 68 22 No No
4 bound 2.05 67.6 27.2 No No
5 empty 2.01 64.7 22.2 No No
6 empty 2.17 65.7 17.3 No No
7 empty 1.95 65.6 14.8 No No
8 empty 1.74 94.4 0 Yes No
9 empty 1.95 52.5 17 No No
10 empty 1.97 60.2 11.4 No No
4G2Z_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.34 67 32.7 Yes Yes
2 bound 1.97 64.7 32.3 No No
3 empty 2.42 64 23.5 No No
4 empty 2.34 59.7 24.7 No No
5 empty 1.99 64.8 16.7 No No
6 empty 2.14 57.9 23.2 No No
7 empty 2.31 67.3 18.3 No No
8 empty 1.72 89.9 0 Yes No
9 empty 1.88 65.7 14.8 No No
10 empty 2.42 52.2 12.4 No No
2OCU_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 64.3 35.7 Yes No
2 bound 2.1 63.5 32.4 No No
3 empty 2.21 63.6 24.9 No No
4 empty 2.21 65.4 21.5 No No
5 empty 2.11 67.7 23.2 No No
6 empty 1.99 61.7 16.2 No No
7 bound 2.12 69.1 14.7 No No
8 bound 2.02 64.4 15.1 No No
9 empty 1.78 93.3 0 Yes No
10 bound 2.4 59.6 9.5 No No
2E1S_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 64.7 32.7 Yes No
2 empty 1.87 64.7 30.4 No No
3 empty 2.32 66.4 20.2 No No
4 empty 2.08 63.2 17.8 No No
5 bound 2.08 64.9 22.5 No No
6 empty 2.14 65 16.2 No No
7 bound 1.94 67.5 14.3 No No
8 empty 2.24 67.9 14.1 No No
9 empty 2.19 56.9 14.2 No No
10 empty 1.72 93.8 0 Yes No
3V5A_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.35 67.4 42.6 Yes Yes
2 bound 1.95 65.3 28.6 No No
3 empty 2.05 58.5 30.1 No No
4 empty 2.29 62.4 24.1 No No
5 empty 2.24 65.9 16.1 No No
6 empty 1.75 93.6 0 Yes No
7 empty 2.2 65.6 13.7 No No
8 empty 1.73 67 16.1 No No
9 bound 2.02 68.3 9.7 No No
10 empty 2.35 51.6 10.2 No No
2PX1_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.93 63.2 31.6 Yes No
2 bound 1.91 64.4 27.7 No No
3 empty 2.2 65.5 23.7 No No
4 bound 1.99 65.2 31.7 No No
5 empty 2.16 65.3 22.3 No No
6 empty 2.07 65.6 16.8 No No
7 empty 2.11 57.6 17 No No
8 empty 1.95 63.3 14.8 No No
9 empty 1.74 92.9 0 Yes No
10 empty 2.08 58.4 12.2 No No
4N6P_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.07 66 33.8 Yes No
2 bound 2.44 69.5 20.2 No No
3 empty 2.34 65.8 20.4 No No
4 empty 1.99 66 22.3 No No
5 empty 2.09 64.9 16.1 No No
6 empty 2.26 67.2 18.2 No No
7 bound 1.81 63.6 13.7 No No
8 empty 1.84 56.6 18.8 No No
9 empty 1.74 94.8 9.6 Yes No
10 empty 2 65.5 14.2 No No
2DXY_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.11 64.2 35.6 Yes No
2 empty 2.2 69.6 20.8 No No
3 empty 1.92 69.7 17.9 No No
4 empty 2.14 63.1 22.5 No No
5 empty 2.1 66 16.9 No No
6 bound 2.11 70 19.4 No No
7 empty 2.26 67.3 16.9 No No
8 bound 1.95 67.4 13.3 No No
9 empty 1.73 96.8 0 Yes No
10 empty 2.3 51.6 17.4 No No
2B65_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.48 65.4 46.3 Yes No
2 bound 2.02 64.1 35.3 No No
3 empty 2.1 65.6 28.7 No No
4 empty 2.04 65.9 15.2 No No
5 empty 2.15 63.8 22.3 No No
6 empty 2.29 65.6 19.7 No No
7 empty 1.78 94.4 9.7 Yes No
8 empty 2.14 61.4 12 No No
9 empty 2.33 60.7 9.2 No No
10 empty 2 70.8 9.3 No No
2DOJ_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.04 64.1 34.3 Yes No
2 empty 1.87 66.6 27 No No
3 empty 2.48 69.9 20.5 No No
4 empty 2.02 64.8 17.1 No No
5 empty 2.09 64.9 20.6 No No
6 bound 1.8 66.4 23.2 No No
7 empty 1.75 95 8.7 Yes No
8 empty 2.14 73.2 13.3 No No
9 empty 2.11 57.9 17.5 No No
10 bound 2.09 64.5 13.5 No No
2Q8J_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.95 65.2 32.6 Yes No
2 empty 1.94 63.8 39.5 No No
3 empty 2.38 66.6 21 No No
4 bound 1.89 66 26.4 No No
5 empty 2.11 62.4 20.1 No No
6 empty 2.16 64.5 20.2 No No
7 empty 1.95 63.5 15.7 No No
8 empty 1.67 91.3 0 Yes No
9 empty 2.31 56.7 15.2 No No
10 empty 2.08 63.6 9.6 No No
3TTR_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 64.3 45.6 Yes No
2 empty 1.96 68.8 20.4 No No
3 empty 2.08 59.4 22 No No
4 bound 1.97 66.1 24.6 No No
5 empty 2.14 68.8 15.9 No No
6 empty 2.29 66.7 16 No No
7 empty 2.26 59.4 20.6 No No
8 empty 1.72 95.9 8.9 Yes No
9 bound 1.96 62.9 14 No No
10 empty 1.99 80.1 9.8 No No
2E0S_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 63 32.3 Yes No
2 empty 1.94 62.7 35.2 No No
3 empty 2.33 66.5 22.8 No No
4 bound 1.97 66.3 34.3 No No
5 empty 2.08 62.9 20.6 No No
6 empty 2.18 65.4 18.2 No No
7 empty 2.03 66.3 16.8 No No
8 empty 2.11 53 17.9 No No
9 empty 1.77 94.2 10.1 Yes No
10 empty 1.97 66 9.4 No No
3IAZ_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.28 62.6 33.7 Yes No
2 empty 1.82 65.2 26.5 No No
3 bound 2.19 65.1 30.7 No No
4 empty 2.4 71.3 21.2 No No
5 empty 2.23 63.3 20.6 No No
6 empty 2.05 65.1 15.2 No No
7 bound 2.03 68 15 No No
8 empty 1.76 94.6 9.1 Yes No
9 empty 2.48 52.8 12.4 No No
10 empty 2.37 59.8 9.7 No No
3IB1_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.15 62.4 34.8 Yes No
2 empty 2.1 66.9 21.5 No No
3 empty 2.43 66 25 No No
4 empty 2.22 60.8 22.5 No No
5 bound 2.05 69.9 16.8 No No
6 empty 2.02 67.9 18.8 No No
7 bound 1.97 65.7 16.3 No No
8 empty 2.23 66.6 15.1 No No
9 empty 1.75 94.3 9.3 Yes No
10 empty 2 65.9 9.4 No No
2DP8_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.54 65.7 44.4 Yes No
2 empty 2 62.5 34.9 No No
3 empty 2.24 63.8 21.6 No No
4 bound 1.89 66.4 19 No No
5 empty 2.19 68.7 17.3 No No
6 empty 1.75 95.1 0 Yes No
7 bound 1.99 63.5 14.9 No No
8 empty 1.93 69 11 No No
9 empty 2.1 64.6 10.5 No No
10 empty 1.94 71.8 10.1 No No
3U8Q_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.23 67.7 34.4 Yes Yes
2 bound 1.96 65.7 30.3 No No
3 empty 2.44 70 18.9 No No
4 empty 2.32 60.2 19.9 No No
5 empty 2.4 66.4 17.3 No No
6 empty 1.83 59.4 20.3 No No
7 empty 1.99 62.7 15.6 No No
8 empty 1.78 94.2 0 Yes No
9 empty 2.42 58.3 11.8 No No
10 empty 1.93 69.8 10.9 No No
2R71_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.52 65.2 46.6 Yes No
2 bound 2.02 65.5 23.7 No No
3 bound 1.97 64.7 25.2 No No
4 empty 2.16 64.5 16.9 No No
5 empty 2.17 65.2 22.7 No No
6 empty 2.22 69.2 17.3 No No
7 empty 1.77 89.7 10 Yes No
8 empty 2.3 66.2 13.8 No No
9 empty 2.35 63.5 8.7 No No
10 empty 1.88 66.8 9.6 No No
2G93_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.49 66.1 43.6 Yes No
2 empty 1.92 68.8 19.8 No No
3 empty 2.14 60.4 23 No No
4 empty 2.04 67.7 18 No No
5 empty 2.17 65.2 21.7 No No
6 empty 2.26 67.7 18.9 No No
7 bound 2.01 66.6 15.4 No No
8 empty 1.73 94 8.9 Yes No
9 empty 2.1 55.2 18.6 No No
10 empty 1.9 67.5 10.4 No No
2DWA_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.92 64 33.4 Yes No
2 empty 2.36 66.9 25.9 No No
3 empty 2.1 63.2 26.9 No No
4 empty 2.21 65.8 20.2 No No
5 bound 2.13 68.2 23.1 No No
6 empty 1.94 63.8 16.5 No No
7 empty 2.2 66.1 18.4 No No
8 bound 2 66.9 17.1 No No
9 empty 1.75 94.2 9 Yes No
10 empty 2.14 57.2 17.1 No No
3TUS_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.56 66.9 44.8 Yes Yes
2 empty 1.94 68.7 19.8 No No
3 empty 2.24 64 25.3 No No
4 empty 1.98 66.1 15.6 No No
5 empty 2.13 65.4 18 No No
6 bound 2 69.8 11.9 No No
7 bound 1.98 65.9 17.5 No No
8 empty 1.66 94.9 0 Yes No
9 empty 2.35 59.8 14.1 No No
10 empty 1.81 66 13.4 No No
2DS9_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.48 65.9 47.4 Yes No
2 empty 1.84 67.2 21.8 No No
3 empty 2 61.2 16.3 No No
4 empty 2.14 69.1 16.3 No No
5 empty 1.94 64.5 14.5 No No
6 bound 2.22 67 15 No No
7 bound 1.97 64.3 16.7 No No
8 empty 2.17 55.5 14.6 No No
9 empty 1.77 92.6 0 Yes No
10 empty 2.15 60.9 10.2 No No
2NWJ_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.46 63.8 45.3 Yes No
2 empty 2.01 62.7 28.4 No No
3 empty 2.13 63.4 20.7 No No
4 empty 2 64.7 15.9 No No
5 bound 2.22 65.7 15.9 No No
6 bound 2.1 69 14.5 No No
7 bound 2.06 63.2 12.9 No No
8 empty 1.69 90.8 10.4 Yes No
9 empty 2.26 56.4 19.7 No No
10 empty 2.38 60.1 9.6 No No
4DXU_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.26 66.3 32.3 Yes Yes
2 bound 1.88 63.8 32.6 No No
3 empty 2.49 66.5 20.3 No No
4 empty 2.25 61.6 23.7 No No
5 empty 1.97 66.7 15.6 No No
6 empty 2.05 60.4 25.9 No No
7 empty 2.31 66 16.4 No No
8 empty 1.72 93 11.3 Yes No
9 empty 1.77 67.9 14.8 No No
10 empty 2.25 59.2 9.3 No No
4NED_A Lactotransferrin Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.17 67 35.8 Yes Yes
2 bound 1.93 68.8 23 No No
3 empty 2.36 64.8 19.5 No No
4 empty 2.18 64.2 20.9 No No
5 empty 1.85 71.2 14.4 No No
6 empty 2.18 65 15.2 No No
7 empty 2.18 69 16.1 No No
8 empty 1.7 94.1 11.3 Yes No
9 bound 1.98 63.6 12.4 No No
10 bound 2.54 54.4 17.3 No No
2R9J_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.02 64.6 32 Yes No
2 empty 2.36 66.3 20.7 No No
3 empty 1.85 68.8 21.1 No No
4 empty 2.13 64.2 18.2 No No
5 bound 1.95 67.6 22.6 No No
6 empty 2 63.8 16.4 No No
7 bound 1.97 65.6 17.1 No No
8 empty 1.76 92.9 8.6 Yes No
9 empty 2.06 57.4 16.6 No No
10 empty 1.91 66.3 12.6 No No
1NKX_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 1.87 61.3 33.8 Yes No
2 empty 2.38 69.3 21.2 No No
3 bound 2.04 65.9 26.7 No No
4 empty 1.88 62.9 25.1 No No
5 empty 2.08 63.5 19.7 No No
6 empty 2.08 65.3 15.4 No No
7 empty 2.27 67.2 14.7 No No
8 empty 1.72 95.7 0 Yes No
9 empty 2.11 50.7 17 No No
10 empty 2.02 66.9 13.1 No No
4G8H_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.12 64.8 32.8 Yes No
2 empty 1.94 66 29.5 No No
3 bound 1.92 63.8 33.7 No No
4 empty 2.32 69.8 19.2 No No
5 empty 2.1 63.5 21.8 No No
6 empty 1.99 63.8 16.6 No No
7 empty 2.25 64.6 17.9 No No
8 empty 1.76 93.3 0 Yes No
9 empty 2.33 60 10.3 No No
10 empty 2.25 56.2 13.7 No No
2DXR_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.42 65.6 46.5 Yes No
2 bound 1.96 65.8 38.1 No No
3 empty 1.98 64.5 32.2 No No
4 empty 2.17 64 21.5 No No
5 empty 1.99 65.5 15.7 No No
6 empty 1.78 95.7 0 Yes No
7 empty 2.31 56.6 21.6 No No
8 empty 2.14 65 10 No No
9 empty 2.49 55.9 10.4 No No
10 empty 2.22 57.4 11.2 No No
2DQV_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.44 62.4 45.6 Yes No
2 empty 2.02 65.3 26.2 No No
3 bound 1.98 65.2 21.2 No No
4 empty 2.07 66.2 16.4 No No
5 empty 2.18 57.2 20.3 No No
6 empty 2.3 69.2 18.3 No No
7 empty 2.23 55.5 17.8 No No
8 bound 1.97 63.9 14.2 No No
9 empty 1.73 91.8 0 Yes No
10 empty 2.31 56.5 14.3 No No
2DWI_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.13 62.1 33.5 Yes No
2 empty 2.4 67.8 23.3 No No
3 empty 1.98 65.6 25.4 No No
4 empty 2.01 66.8 24.8 No No
5 empty 2.25 63.4 19.8 No No
6 empty 2.16 66.8 17.9 No No
7 empty 2.08 67.2 15.5 No No
8 bound 1.94 64.8 14 No No
9 empty 2.07 57.2 18.3 No No
10 empty 1.75 93.7 8.9 Yes No
3KJ7_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.05 63.9 33.3 Yes No
2 empty 1.94 67.3 28.5 No No
3 empty 2.4 65.5 21.7 No No
4 empty 2.2 64.7 20.6 No No
5 bound 1.91 68.9 22.6 No No
6 empty 2.01 65.6 16.6 No No
7 empty 2.16 66.5 17.4 No No
8 bound 1.9 62.2 16.4 No No
9 empty 1.72 94 9.3 Yes No
10 empty 2.28 56.3 16.7 No No
1BLF_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 73.2 22.6 Yes No
2 bound 2.12 67.3 33 No No
3 empty 1.56 71.9 31.1 No No
4 empty 1.72 72.4 21.3 No No
5 empty 2.15 62.7 27.2 No No
6 empty 2.22 65.9 27.7 No No
7 bound 1.84 64.8 21.7 No No
8 empty 2.19 64.1 22.1 No No
9 empty 2.18 62.7 27.5 No No
10 bound 2.18 65.4 24.2 No No
2FA7_A Lactotransferrin Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.54 65.2 44.5 Yes No
2 empty 1.96 63.2 26.5 No No
3 empty 2.18 63.3 20.5 No No
4 bound 1.88 66.3 23 No No
5 empty 2.32 70.6 18.7 No No
6 bound 1.97 64 18.2 No No
7 empty 1.71 94.9 9.1 Yes No
8 empty 2.41 64.7 9.9 No No
9 empty 2.15 56.2 14.3 No No
10 empty 2.36 59.4 9.8 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed56
Domains assessed as druggable using the strict criteria6
Domains assessed as druggable using the relaxed criteria56

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1BLF_A (35859) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.8Å Yes Yes
1BLF_A (35860) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.8Å Yes Yes
1NKX_A (91943) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.9Å Yes No
1SDX_A (98812) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.06Å Yes No
1SDX_E (98812) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.06Å Yes No
2ALU_A (126981) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.09Å Yes No
2AYS_A (127570) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.86Å Yes No
2B65_A (127953) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.5Å Yes No
2DOJ_A (131604) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.4Å Yes No
2DP8_A (131608) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.5Å Yes No
2DQV_A (131643) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.7Å Yes No
2DS9_A (131687) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.78Å Yes No
2DSF_A (131688) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.8Å Yes No
2DVC_A (131777) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 3Å Yes No
2DWA_A (131848) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.07Å Yes No
2DWH_A (131851) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.8Å Yes No
2DWI_A (131852) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.2Å Yes No
2DWJ_A (131853) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.3Å Yes No
2DXR_A (131878) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.85Å Yes No
2DXY_A (131879) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.03Å Yes No
2DYX_A (131955) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2Å Yes No
2E0S_A (131956) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.15Å Yes No
2E1S_A (131971) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.7Å Yes No
2FA7_A (133184) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.38Å Yes No
2G93_A (134789) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.9Å Yes No
2H4I_A (136075) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.55Å Yes No
2HCA_A (136324) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.8Å Yes No
2NUV_A (138623) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.25Å Yes No
2NWJ_A (138719) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.75Å Yes No
2O1L_A (138873) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.97Å Yes No
2O51_A (138917) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 3Å Yes No
2OCU_A (139020) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.38Å Yes No
2P1S_A (139458) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.93Å Yes No
2PX1_A (139774) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.5Å Yes No
2Q8J_A (139890) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.7Å Yes No
2QJE_A (150829) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.3Å Yes No
2R71_A (151625) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.07Å Yes No
2R9J_A (151788) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.5Å Yes No
2ZMB_A (154689) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.9Å Yes No
3CFL_A (156613) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.25Å Yes No
3CI8_A (156663) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.4Å Yes No
3CRB_A (156945) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.6Å Yes No
3E9X_A (158073) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.7Å Yes No
3IAZ_A (4059925) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2Å Yes No
3IB0_A (4087126) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 1.4Å Yes No
3IB1_A (4178064) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.2Å Yes No
3IB2_A (4191431) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.29Å Yes No
3K0V_A (3490564) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, UNMATCHED 1.91Å Yes No
3KJ7_A (3500976) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, UNMATCHED 1.91Å Yes No
3MJN_A (3550315) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, UNMATCHED 2.38Å Yes No
3O97_A (3570399) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, UNMATCHED 2.68Å Yes No
3RGY_A (4078624) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2Å Yes No
3SDF_A (4066154) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.1Å Yes Yes
3TAJ_A (3710758) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, UNMATCHED 1.7Å Yes Yes
3TOD_A (3710897) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, UNMATCHED 1.38Å Yes Yes
3TTR_A (4007445) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.27Å Yes No
3TUS_A (4151350) Lactotransferrin Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin 2.5Å Yes Yes
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score