Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ascG (P24242) - Overview - Molecular Target Synopsis

Protein


ascG, HTH-type transcriptional regulator AscG
UniProt P24242

Also Known as ASCG_ECOLI, ascG

Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene.

3DBI
CRYSTAL STRUCTURE OF SUGAR-BINDING TRANSCRIPTIONAL REGULATOR (LACI FAMILY) FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE
RCSB/PDB
Inspect Structure
See all 3D Structures for ascG

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
336P24242-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project ascG has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For ascG there are:
2 structures (5 chains) solved
1 are solved in complex with at least one small molecule ligand
1 are solved with an approved drug

ascG is solved in complex with the approved drug(s):

FRU/FRUCTOSE (3BRQ_A).

(see details)
Molecular Target 3D Synopsis