PREP, Prolyl endopeptidase
Enzyme Classification 188.8.131.52
Also Known as
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
Isoforms / Transcripts (Protein Coding)
UniProt: PREP is active in the following subcellular-locations: cytoplasm.
GO terms: PREP is active in the following subcellular-locations: cytoplasm, cytosol.
Gene Copy Number Variation
In COSMIC - Cell Lines Project PREP has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)
Screening and Chemistry
PREP has been screened with 169 compounds (207 bioactivities), 147 compounds have bioactivities that show binding affinity of <= 500nM (181 bioactivities). (see details)