SLC2A5 (P22732) - Overview - Molecular Target Synopsis
SLC2A5, Solute carrier family 2, facilitated glucose transporter member 5
Also Known as GTR5_HUMAN, SLC2A5, GLUT5
Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low efficiency (PubMed:1695905). Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: SLC2A5 is active in the following subcellular-locations: apical cell membrane, cell membrane, sarcolemma.
GO terms: SLC2A5 is active in the following subcellular-locations: apical plasma membrane, extracellular exosome, integral component of plasma membrane, plasma membrane, sarcolemma, specific granule membrane.