Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpl14 (P22450) - Overview - Molecular Target Synopsis

Protein


rpl14, 50S ribosomal protein L14
UniProt P22450

Also Known as RL14_HALMA, rpl14

Forms part of two intersubunit bridges in the 70S ribosome (By similarity). Binds to 23S rRNA. The L3/L14/L24e cluster may contact the 16S rRNA in 2 intersubunit bridges (By similarity). Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e.

3OW2
CRYSTAL STRUCTURE OF ENHANCED MACROLIDE BOUND TO 50S RIBOSOMAL SUBUNIT
RCSB/PDB
Inspect Structure
See all 3D Structures for rpl14

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
132P22450-1

Sub-cellular localization


GO terms: rpl14 is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpl14 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpl14 there are:
67 structures (67 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis