Molecular Target Synopsis
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RPB10 (P22139) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 07/05/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 07/05/2019)


Chains assessed173
Chains with at least one site assessed as druggable using the strict criteria1
Chains with at least one site assessed as druggable using the relaxed criteria19


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
2R92_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 60.5 17.7 No No
2 empty 1.46 62.8 13.1 No No
3 empty 2.01 65.2 11.5 No No
4 empty 1.55 55 10.9 No No
5 empty 2.46 60.8 8.6 No No
6 empty 2.82 51.2 6.8 No No
7 empty 2.46 67.7 7.2 No No
8 empty 1.39 68.8 7.5 No No
9 empty 3.16 60 6.2 No No
10 empty 2.66 62.6 5.9 No No
3M4O_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 55 21.9 No No
2 empty 1.4 60.1 16.3 No No
3 empty 1.48 54.8 10.8 No No
4 empty 2.51 54.7 11 No No
5 empty 1.79 58 9.7 No No
6 empty 2.39 57.3 10.8 No No
7 empty 2.99 61.8 9.1 No No
8 empty 3.5 42.1 7.6 No No
9 empty 1.42 64.8 7 No No
10 empty 1.67 59.5 5.2 No No
3S2D_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 58.9 20.6 No No
2 empty 1.61 64 12 No No
3 empty 1.73 57.3 9.6 No No
4 empty 1.86 52 9.8 No No
5 empty 2.51 56 9 No No
6 empty 1.51 62.8 8.1 No No
7 empty 2.33 50.8 8.6 No No
8 empty 3.02 58.7 6.3 No No
9 empty 3.24 66.4 6.9 No No
6F41_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.74 56.1 19.7 No No
2 empty 1.58 63.6 18.2 No No
3 empty 1.7 68.8 9.4 No No
4 empty 1.06 57.4 9.6 No No
5 empty 2.31 49.5 9.7 No No
6 empty 1.95 63.7 7.6 No No
7 empty 2.31 63.4 9.3 No No
8 empty 1.6 52.4 6.9 No No
9 empty 2.35 57.7 5.5 No No
10 empty 3.27 57.1 5.8 No No
4V1O_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.21 59.8 22.5 No No
2 empty 1.77 66.2 12.3 No No
3 empty 1.72 50.5 9.3 No No
4 empty 1.9 51.7 7.4 No No
5 empty 2.13 78 5.9 No No
6 empty 2.66 62.3 6.4 No No
7 empty 3.75 49.5 5.3 No No
8 empty 2.4 52.4 6.4 No No
9 empty 3.08 56.8 5.2 No No
10 empty 2.02 73.5 5.9 No No
4A3K_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.21 58.6 21.6 No No
2 empty 1.54 62.2 13.6 No No
3 empty 1.59 62.1 10.3 No No
4 empty 2.87 63 6.7 No No
5 empty 1.85 55.8 7.7 No No
6 empty 2.4 75.4 5.7 No No
7 empty 3.58 52.8 7.3 No No
8 empty 2.44 51.9 6.3 No No
9 empty 2.81 53.1 5.7 No No
10 empty 2.86 59.6 6.8 No No
4BY1_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 62.3 19.8 No No
2 empty 1.45 61.7 12.5 No No
3 empty 1.86 51.5 9.6 No No
4 empty 2.02 62.4 7.7 No No
5 empty 2.23 75.6 7 No No
6 empty 2.4 51.7 7.6 No No
7 empty 2.07 55 7.4 No No
8 empty 1.37 57.7 8.3 No No
9 empty 3.05 61.1 6.5 No No
10 empty 3.8 51.2 5.2 No No
6BLP_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 56.9 21 No No
2 empty 1.25 60.6 15.4 No No
3 empty 1.71 59.6 9.9 No No
4 empty 1.9 52.6 11.5 No No
5 empty 1.77 61.9 6.8 No No
6 empty 2.08 62.7 5.2 No No
7 empty 3.73 51.6 6.2 No No
2JA7_V DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 57 20.7 No No
2 empty 1.4 61.4 12.6 No No
3 empty 2.04 62.9 12.7 No No
4 empty 1.75 52.2 10.4 No No
5 empty 2.92 48.3 10 No No
6 empty 2.65 77.2 8.4 No No
7 empty 1.47 62.8 7.4 No No
8 empty 3.21 56.1 5.8 No No
9 empty 3 53.9 5.6 No No
10 empty 2.07 61.6 8.4 No No
3S17_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.97 60.2 27 Yes No
2 empty 1.7 58 10.6 No No
3 empty 1.92 59.9 10.7 No No
4 empty 1.87 58.6 8.2 No No
5 empty 3.05 64.3 9 No No
6 empty 2.94 54.4 7.2 No No
7 empty 3.56 44.4 6.5 No No
8 empty 3.15 57.1 6.2 No No
9 empty 2.79 66.2 0 No No
10 empty 1.69 64.4 4.4 No No
5C44_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 63.1 22.6 No No
2 empty 1.46 64.1 12.8 No No
3 empty 1.64 52 9.6 No No
4 empty 2.07 78 6.1 No No
5 empty 1.3 65.9 4.5 No No
6 empty 2.62 61.5 6.6 No No
7 empty 2.62 83.5 0 No No
8 empty 3.09 54.7 6.7 No No
9 empty 2.58 60.9 6.8 No No
10 empty 1.92 58 6.8 No No
3M3Y_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 56.3 18.4 No No
2 empty 1.4 61.7 16.8 No No
3 empty 1.7 61.4 11.2 No No
4 empty 1.94 52.6 13.2 No No
5 empty 2.53 44.2 6.3 No No
6 empty 2.17 52 6.8 No No
7 empty 1.33 65.9 5 No No
4A3C_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 60.3 24.6 Yes No
2 empty 1.65 64.8 13.9 No No
3 empty 1.64 52.1 9.6 No No
4 empty 2.11 65.4 8.5 No No
5 empty 2.38 53.8 6.8 No No
6 empty 2.21 51 6.6 No No
7 empty 2.37 62.3 8.6 No No
8 empty 3.86 58.3 5.6 No No
9 empty 3.04 59.5 4.7 No No
10 empty 1.6 63.5 5.4 No No
6EU1_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 64 20.8 No No
2 empty 1.43 63.6 14.5 No No
3 empty 2.66 58.6 8.3 No No
4 empty 2.51 47.4 8.9 No No
5 empty 1.78 64.7 6.8 No No
6 empty 2.54 62.3 7 No No
7 empty 1.94 56 7.3 No No
8 empty 1.53 57.5 6.4 No No
9 empty 2.64 73 6.9 No No
10 empty 1.76 62.2 5.9 No No
5OQM_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 57.8 22.2 No No
2 empty 1.63 61.4 11.3 No No
3 empty 1.43 53.1 9 No No
4 empty 2.93 60.2 7.2 No No
5 empty 2.94 64.6 5.5 No No
6 empty 3.01 58.7 6.3 No No
7 empty 3.14 53.6 6.4 No No
8 empty 1.69 59.3 7.2 No No
9 empty 1.82 47.9 6.9 No No
10 empty 3.02 71.6 5.5 No No
1TWC_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 62.4 18.6 No No
2 empty 1.44 61.4 14.9 No No
3 empty 1.85 63.4 7.9 No No
4 empty 2.59 52.3 8.2 No No
5 empty 2.13 52 8.3 No No
6 empty 2.09 58.1 7 No No
7 empty 3.61 55.6 6.5 No No
8 empty 3.06 49.2 7.3 No No
9 empty 1.52 64.4 5.5 No No
10 empty 1.48 61.8 6.3 No No
2NVY_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.28 59.9 22 No No
2 empty 1.4 64.8 12.2 No No
3 empty 1.92 56.9 10.5 No No
4 empty 2.92 45.5 6.6 No No
5 empty 1.51 59.5 5.4 No No
6 empty 1.52 62.4 4.8 No No
7 empty 2.87 75.3 5.8 No No
8 empty 2.03 66.7 5.1 No No
9 empty 2.36 61.5 6.1 No No
10 empty 3.42 56.1 6.4 No No
5N60_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.3 58.9 18.9 No No
2 empty 1.7 59.9 18.2 No No
3 empty 1.82 65.6 12 No No
4 empty 1.74 60.9 8.8 No No
5 empty 2.48 51.3 9.9 No No
6 empty 2.35 56.2 8.2 No No
7 empty 2.64 66.4 7.9 No No
8 empty 2.68 50.7 9.6 No No
9 empty 2.39 60.2 7 No No
10 empty 1.73 58.7 6.5 No No
3CQZ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 59.6 20.7 No No
2 empty 1.49 64.1 17.9 No No
3 empty 1.71 56.8 8.9 No No
4 empty 1.98 55.3 8.8 No No
5 empty 1.97 53.6 10 No No
6 empty 2.78 56 6.1 No No
7 empty 3.03 57.1 6.1 No No
8 empty 3.77 48.5 7.1 No No
9 empty 1.53 57.8 6.3 No No
3GTP_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 53.6 20.1 No No
2 empty 1.3 60.7 12 No No
3 empty 1.81 53.8 10 No No
4 empty 1.76 59.3 10.4 No No
5 empty 2.7 58.1 10.1 No No
6 empty 2.98 67.2 9.6 No No
7 empty 2.92 66.4 6.7 No No
8 empty 3.63 43.3 6.1 No No
9 empty 1.39 67.5 7 No No
10 empty 3.2 58.8 6.3 No No
5LMX_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 54.2 21.3 No No
2 empty 2.13 56.9 18.3 No No
3 empty 1.83 61.1 14.3 No No
4 empty 1.8 61.3 9.7 No No
5 empty 2.24 59.1 10.1 No No
6 empty 2.82 75.5 7.6 No No
7 empty 1.57 60 7.5 No No
8 empty 1.97 70.7 7.2 No No
9 empty 2.68 67.8 4.6 No No
10 empty 2.58 63.7 5.2 No No
5FJ8_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 62.5 22.8 No No
2 empty 1.63 64.5 16 No No
3 empty 2.46 51.8 11.4 No No
4 empty 1.92 65.4 8.8 No No
5 empty 1.39 54.3 7.5 No No
6 empty 1.49 71.1 7.7 No No
7 empty 1.47 54.7 8 No No
8 empty 2.46 75.9 7.1 No No
9 empty 2.11 73.4 4.9 No No
10 empty 1.82 61.5 4.7 No No
5OT2_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 60.2 17.8 No No
2 empty 1.58 63.5 13 No No
3 empty 1.95 47.3 10.6 No No
4 empty 1.76 64.9 8.6 No No
5 empty 2.55 61.3 7.8 No No
6 empty 2.26 61.6 8.4 No No
7 empty 1.85 63.3 5 No No
8 empty 1.44 64.9 7.5 No No
9 empty 4 53.6 6.3 No No
10 empty 3.3 59.5 0 No No
5W66_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 56.2 22.9 No No
2 empty 2.64 54.9 14.2 No No
3 empty 1.77 63.4 10.7 No No
4 empty 1.04 56 10.8 No No
5 empty 1.91 61.3 9.3 No No
6 empty 1.9 60.1 8.2 No No
7 empty 3.3 61 6.2 No No
8 empty 2.68 65.3 4.8 No No
9 empty 2.5 54.2 7.2 No No
4A3G_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.36 60.7 28.6 Yes No
2 empty 1.47 64 13.5 No No
3 empty 1.51 54.1 10.1 No No
4 empty 1.91 52.5 8.1 No No
5 empty 3.51 51.9 6.9 No No
6 empty 3.1 57.5 6 No No
7 empty 2.45 63 6.2 No No
8 empty 2.53 54.1 5.8 No No
9 empty 1.71 63 6.3 No No
10 empty 2.94 62.7 5.4 No No
3GTK_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 54.5 18.7 No No
2 empty 1.56 61.7 12.7 No No
3 empty 1.78 59.2 10.1 No No
4 empty 1.5 50.7 10.8 No No
5 empty 1.61 61.1 7.4 No No
6 empty 2.65 63.5 7.1 No No
7 empty 3.18 57.6 6.7 No No
8 empty 2.33 73.1 0 No No
9 empty 3.61 43.1 6.7 No No
10 empty 2.18 55.2 7.6 No No
4Y7N_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 56.1 21.3 No No
2 empty 1.12 61.8 15 No No
3 empty 1.83 59.2 10.1 No No
4 empty 1.67 55.3 11.3 No No
5 empty 3.21 59.5 8.8 No No
6 empty 3.69 48 7.9 No No
7 empty 1.53 63.9 4.8 No No
8 empty 1.12 75.4 5 No No
3K1F_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 58 23.5 No No
2 empty 1.43 63.7 14.9 No No
3 empty 1.56 56.2 9.6 No No
4 empty 2.82 64.6 7.2 No No
5 empty 1.78 55.1 7.5 No No
6 empty 1.88 54.9 8.5 No No
7 empty 1.62 59.6 6.8 No No
8 empty 3.1 56.2 5.9 No No
9 empty 2.65 62.1 6.2 No No
10 empty 2.92 63 5.4 No No
5IP9_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 58.8 21.6 No No
2 empty 1.72 62.1 11.7 No No
3 empty 2.02 60.5 8.4 No No
4 empty 1.63 53.8 10.9 No No
5 empty 2.37 52.5 7.3 No No
6 empty 1.49 64.2 6.5 No No
7 empty 2.5 57.1 5.9 No No
8 empty 3.34 53.2 6.1 No No
4A3J_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 60 21.9 No No
2 empty 1.78 61.3 12 No No
3 empty 1.6 53.8 9.9 No No
4 empty 2.1 58.1 10.8 No No
5 empty 2.79 59.4 7.5 No No
6 empty 3.1 53.7 6.9 No No
7 empty 2.5 52.5 5.9 No No
8 empty 2.65 64.3 5.1 No No
9 empty 1.97 58.6 6.4 No No
10 empty 2.21 55.7 5.2 No No
4A3F_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 57.8 24.5 Yes No
2 empty 1.64 61.7 14.7 No No
3 empty 1.66 53.4 9.2 No No
4 empty 2.53 75.7 6.8 No No
5 empty 1.88 57 7.9 No No
6 empty 2.07 70.4 6 No No
7 empty 3.07 61.5 6.3 No No
8 empty 3.32 61.4 5.4 No No
9 empty 2.63 51.6 5.6 No No
10 empty 2.89 56.6 5.1 No No
5M5X_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.84 52.8 18.1 No No
2 empty 2.54 51.1 14.9 No No
3 empty 1.58 62.8 8.7 No No
4 empty 1.43 53 10.4 No No
5 empty 1.95 66.5 9.1 No No
6 empty 1.38 58.2 7.7 No No
7 empty 2.48 56.7 10 No No
8 empty 3.05 64.3 5.8 No No
9 empty 2.54 62.6 9.4 No No
10 empty 2.6 66.7 4.8 No No
1TWA_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 62.2 18.1 No No
2 empty 1.48 62.1 13.9 No No
3 empty 1.84 61.9 8.7 No No
4 empty 2.06 54.2 9.8 No No
5 empty 2.7 54.5 8.1 No No
6 empty 2.55 53.3 6.5 No No
7 empty 2.99 54 7.7 No No
8 empty 3.72 56.6 5 No No
9 empty 1.39 59 6.3 No No
10 empty 1.57 62.3 5.2 No No
4C2M_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.34 56.2 20 No No
2 empty 1.69 60.6 18.4 No No
3 empty 1.81 62.9 12.1 No No
4 empty 1.84 62.3 8.3 No No
5 empty 2.25 68 6.9 No No
6 empty 2.56 67.5 7.2 No No
7 empty 2.34 52.6 7.8 No No
8 empty 2.66 46.6 9.3 No No
9 empty 2.36 56.1 8 No No
10 empty 1.62 61.5 5.5 No No
4BBR_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 61.6 18.3 No No
2 empty 1.49 63.6 13.8 No No
3 empty 1.89 61.5 8.4 No No
4 empty 2.18 50.8 12.2 No No
5 empty 2.23 57.9 12.1 No No
6 empty 2.81 54.5 9.8 No No
7 empty 2.49 59 7.1 No No
8 empty 2.56 63.8 7.8 No No
9 empty 3.75 55.3 5.5 No No
10 empty 2.45 52.4 6.4 No No
3HOU_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 58.6 20.8 No No
2 empty 1.2 64.6 11.3 No No
3 empty 2.12 52 9.7 No No
4 empty 2.89 57.8 8.6 No No
5 empty 1.39 66.4 6.6 No No
6 empty 2.87 52.6 8.6 No No
7 empty 2.26 60 6.2 No No
8 empty 3.55 59.3 5.8 No No
9 empty 3.81 42.7 5.8 No No
5OA1_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 54.2 21.3 No No
2 empty 2.14 58.2 17.4 No No
3 empty 1.8 67.4 12.8 No No
4 empty 1.79 64.3 10 No No
5 empty 2.69 69.6 9.1 No No
6 empty 1.54 66 9.2 No No
7 empty 2.5 57.3 6.5 No No
8 empty 2.06 67.4 5.8 No No
9 empty 2.45 57.3 5.9 No No
10 empty 3.15 54.8 6.6 No No
4A3D_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 56.8 22.9 No No
2 empty 1.79 64.7 13.7 No No
3 empty 1.7 51.9 9.7 No No
4 empty 2.11 73.9 6.7 No No
5 empty 1.91 54.7 7.7 No No
6 empty 2.64 59.8 7.7 No No
7 empty 3.67 53.3 6 No No
8 empty 1.57 59.2 7.5 No No
9 empty 2.43 50.7 6.2 No No
10 empty 3.38 60 5.1 No No
1I50_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.2 60.5 18.8 No No
2 empty 1.51 66.9 12.8 No No
3 empty 1.7 58 10.1 No No
4 empty 1.96 63.6 7.5 No No
5 empty 1.34 54.8 7.1 No No
6 empty 2.43 75.4 7.4 No No
7 empty 1.92 67.5 6.5 No No
8 empty 1.93 50 8.6 No No
9 empty 3.88 51.7 6.8 No No
10 empty 3.43 56.6 6.4 No No
5FMF_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 59.1 22.4 No No
2 empty 1.76 61.3 13.5 No No
3 empty 1.66 47.5 10.1 No No
4 empty 1.92 54.5 7.8 No No
5 empty 2.14 70.2 6.2 No No
6 empty 2.34 57.1 6.2 No No
7 empty 2.73 57.9 5.6 No No
8 empty 3.5 47.9 5.6 No No
9 empty 1.46 55.4 5.9 No No
10 empty 3.23 54 6 No No
1WCM_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 61.7 21.9 No No
2 empty 1.51 61 13.1 No No
3 empty 1.59 56.3 11 No No
4 empty 2.58 72.6 7.7 No No
5 empty 2.92 56.2 8.2 No No
6 empty 1.43 64.1 7.5 No No
7 empty 3.2 63.9 6.6 No No
8 empty 2.33 62.6 5.8 No No
9 empty 1.07 66.3 5.8 No No
10 empty 3.59 44.6 4.8 No No
5W5Y_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 57.3 19 No No
2 empty 2.6 57 16 No No
3 empty 1.72 64.4 10.9 No No
4 empty 1.14 54.6 11.7 No No
5 empty 1.82 57.4 10 No No
6 empty 1.99 59.5 7.2 No No
7 empty 2.81 78.1 0 No No
8 empty 3.32 69.4 0 No No
9 empty 1.03 61.6 0 No No
10 empty 2.63 67.1 5.1 No No
3GTM_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 59 23.7 No No
2 empty 1.57 60.9 16.9 No No
3 empty 1.89 52.8 11.2 No No
4 empty 2.43 62.2 8.6 No No
5 empty 1.71 65.8 7.3 No No
6 empty 2.56 55.6 7.8 No No
7 empty 2.8 58.8 6.4 No No
8 empty 3.48 41.1 6.8 No No
9 empty 2.3 48.9 6.4 No No
10 empty 1.93 44.6 5.7 No No
4BXX_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 58.1 23.8 No No
2 empty 1.77 64.5 13.3 No No
3 empty 1.57 52 10.7 No No
4 empty 2.36 54 7.8 No No
5 empty 2.15 78.3 0 No No
6 empty 1.67 59.6 7.4 No No
7 empty 3.77 50 5 No No
8 empty 1.48 59.5 6 No No
9 empty 3.32 50.6 6.2 No No
5FJ9_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.94 63.3 22.4 No No
2 empty 1.58 61.5 14.7 No No
3 empty 2.14 49.8 11.6 No No
4 empty 2.02 69.4 7.2 No No
5 empty 1.33 54.3 8.4 No No
6 empty 1.53 78.6 6.8 No No
7 empty 1.43 55.9 7.3 No No
8 empty 2.33 52.6 8.3 No No
9 empty 2.51 71.8 6.4 No No
10 empty 1.96 62.3 4.9 No No
5M3F_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.36 57.7 19.6 No No
2 empty 1.7 56.1 17.7 No No
3 empty 1.78 60.2 12.9 No No
4 empty 1.84 60.4 9.3 No No
5 empty 2.9 68.7 8.2 No No
6 empty 2.32 63.1 8.5 No No
7 empty 2.37 54.4 13 No No
8 empty 2.69 62.4 8.7 No No
9 empty 1.79 60.2 5.4 No No
10 empty 2.57 58 6.5 No No
3J0K_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 61.5 22.2 No No
2 empty 1.48 62.2 13.3 No No
3 empty 1.55 52.4 10.6 No No
4 empty 2.73 59.9 10.8 No No
5 empty 2.53 60.8 6.6 No No
6 empty 3.01 68.8 6.4 No No
7 empty 3.25 60 6.3 No No
8 empty 1.58 62.6 5 No No
9 empty 1.58 53 6.6 No No
10 empty 2.5 57.5 5.1 No No
3GTO_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 53.7 20 No No
2 empty 1.35 60.5 12.6 No No
3 empty 1.75 58.9 9.2 No No
4 empty 1.66 60.7 9.1 No No
5 empty 3.06 62.5 7.3 No No
6 empty 2.26 71.4 5 No No
7 empty 2.94 71.8 6 No No
8 empty 2.92 48.6 7.3 No No
9 empty 1.99 64.7 5.8 No No
10 empty 1.24 55.1 7.1 No No
2NVZ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 55.9 16.9 No No
2 empty 1.82 57.8 15.5 No No
3 empty 1.44 61.1 13.2 No No
4 empty 1.67 55.6 10.5 No No
5 empty 2.3 65.2 9.7 No No
6 empty 1.07 64.2 8 No No
7 empty 2.53 64.9 6.1 No No
8 empty 1.48 63.5 7.5 No No
9 empty 3.24 68.7 6.4 No No
10 empty 3 60.7 7.2 No No
5M3M_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 53.3 20.9 No No
2 empty 1.81 59.5 20 No No
3 empty 1.63 60.1 15.5 No No
4 empty 1.82 67.7 8.8 No No
5 empty 2.89 73.4 9.6 No No
6 empty 2.57 48.3 8.1 No No
7 empty 2.67 61.1 7.7 No No
8 empty 2.15 70.2 7.9 No No
9 empty 1.6 62.1 6.1 No No
10 empty 3.19 55.8 6.3 No No
5G5L_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.84 57.7 16.4 No No
2 empty 1.69 59.7 19.4 No No
3 empty 1.82 64.2 12.5 No No
4 empty 1.28 55.2 12 No No
5 empty 1.78 60.3 8 No No
6 empty 2.2 66.5 4.1 No No
7 empty 2.61 67.6 6.3 No No
8 empty 2.61 45 8.8 No No
9 empty 2.82 53.7 8.9 No No
10 empty 2.54 61.5 10 No No
2JA6_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 60.1 21.3 No No
2 empty 1.41 61.2 13.6 No No
3 empty 1.7 53.1 11.2 No No
4 empty 2.45 71.4 10.7 No No
5 empty 2.86 55.1 9.8 No No
6 empty 2.91 53.5 9.3 No No
7 empty 1.92 59.5 10.1 No No
8 empty 2.16 57.4 9.2 No No
9 empty 1.7 67.1 6.3 No No
10 empty 2.88 45.3 6.1 No No
1Y1V_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 61.8 21.5 No No
2 empty 1.47 65.1 13.6 No No
3 empty 1.55 55.1 10.8 No No
4 empty 2.73 57.7 10.3 No No
5 empty 2.8 72.9 7.3 No No
6 empty 2.42 60.3 8 No No
7 empty 1.51 64.6 6.1 No No
8 empty 1.82 47.2 7.6 No No
9 empty 3.03 52.6 5.5 No No
10 empty 2.48 50.6 6.1 No No
6EU2_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 59.9 22.9 No No
2 empty 1.51 59.4 15.9 No No
3 empty 1.33 56.1 11.9 No No
4 empty 1.94 50.2 10.7 No No
5 empty 1.95 67.5 11.3 No No
6 empty 2.36 51.9 8.7 No No
7 empty 2.38 55.4 7.8 No No
8 empty 2.08 56.7 7.5 No No
9 empty 3.07 52.5 7.7 No No
2E2H_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 58.5 22 No No
2 empty 1.4 60.8 15.2 No No
3 empty 1.57 54.6 11.4 No No
4 empty 1.78 61.2 9.8 No No
5 empty 1.37 63.7 7.6 No No
6 empty 1.33 70.2 7.2 No No
7 empty 2.75 57.5 10 No No
8 empty 3.36 65.3 0 No No
9 empty 3.07 59.4 6.8 No No
10 empty 2.26 60.6 6.7 No No
3GTG_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 59.6 21.2 No No
2 empty 1.49 57.1 15.8 No No
3 empty 1.59 55.3 11.4 No No
4 empty 1.8 58.6 10.9 No No
5 empty 1.69 60.7 7.8 No No
6 empty 2.26 64 7.2 No No
7 empty 2.82 63.4 6.3 No No
8 empty 2.68 55.6 7.7 No No
9 empty 3.11 54 7.3 No No
10 empty 1.19 61.1 6.7 No No
5C4X_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 59.6 18.2 No No
2 empty 2.34 48.7 16.3 No No
3 empty 1.42 61.2 13.7 No No
4 empty 1.77 62.9 8.6 No No
5 empty 1.71 85.9 0 Yes No
6 empty 1.17 57.8 7.5 No No
7 empty 2.94 64 9.7 No No
8 empty 2.41 63.8 6.8 No No
9 empty 2.79 48 6.3 No No
10 empty 1.71 55.7 7.4 No No
3PO3_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 56.3 18 No No
2 empty 1.42 63.8 12 No No
3 empty 1.54 55.5 10.2 No No
4 empty 2.04 63.2 8.4 No No
5 empty 2.73 54.2 10.6 No No
6 empty 1.38 66.4 8.8 No No
7 empty 2.37 55 8.2 No No
8 empty 2.22 49 7.2 No No
9 empty 3.62 57 5.3 No No
10 empty 2.85 60.5 6 No No
2R93_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 56.6 20.7 No No
2 empty 1.97 64.2 13.9 No No
3 empty 1.41 63.5 11.7 No No
4 empty 1.63 52.1 10.6 No No
5 empty 2.53 65 8.7 No No
6 empty 2.91 60.2 9.7 No No
7 empty 2.62 69.7 7.6 No No
8 empty 2.07 57 8 No No
9 empty 2.39 59.2 7.8 No No
10 empty 2.73 46.3 7.6 No No
4V1M_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.2 58.9 21.4 No No
2 empty 1.76 63.8 14.4 No No
3 empty 1.72 50 9.3 No No
4 empty 2.1 58.2 9.2 No No
5 empty 2.19 83 0 No No
6 empty 2.67 59.6 7.3 No No
7 empty 2.94 59.2 7.1 No No
8 empty 3.6 51.4 7.6 No No
9 empty 2.45 50.7 5.5 No No
10 empty 2.79 51.5 5 No No
5C3E_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 60.7 22.2 No No
2 empty 1.44 50.9 13.2 No No
3 empty 1.54 60.8 16.4 No No
4 empty 2.08 56.6 7.7 No No
5 empty 2.58 65.6 7.6 No No
6 empty 1.05 51.1 5.8 No No
7 empty 2.54 64.1 4.9 No No
8 empty 3.26 61.6 4.7 No No
9 empty 2.94 54.4 5.5 No No
10 empty 2.54 55.7 6 No No
3S2H_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 59.9 23.7 No No
2 empty 1.54 65.1 11.7 No No
3 empty 1.51 54.3 10.7 No No
4 empty 1.99 53.4 7.3 No No
5 empty 3.29 56.6 6 No No
6 empty 3.68 43.2 6.3 No No
7 empty 1.57 58.1 6 No No
8 empty 1.6 69.4 5.9 No No
9 empty 3.15 50 6 No No
6CNB_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.86 61.9 21.6 No No
2 empty 1.32 59.3 17.2 No No
3 empty 2.86 46.3 8.5 No No
4 empty 2.36 55.6 9.3 No No
5 empty 2.04 65 6.3 No No
6 empty 1.77 50 7.2 No No
7 empty 2.74 76.1 7.1 No No
8 empty 1.52 60 6.6 No No
9 empty 2.84 60.2 7.6 No No
10 empty 2.75 60.6 6.1 No No
3S16_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 56.1 20.9 No No
2 empty 1.42 63.8 13.4 No No
3 empty 1.8 59.7 9.7 No No
4 empty 1.59 56.7 10.6 No No
5 empty 2.22 53 10.7 No No
6 empty 2.88 73.6 0 No No
7 empty 2.73 54.9 7.3 No No
8 empty 2.52 64.1 5.5 No No
9 empty 3.29 69.9 4 No No
10 empty 3.07 69.4 6.3 No No
4C3J_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 53.3 18.6 No No
2 empty 2.14 58.1 19.8 No No
3 empty 1.82 65.4 12.9 No No
4 empty 1.79 63.6 9.1 No No
5 empty 2.44 71.4 7.3 No No
6 empty 2.44 55.9 12.7 No No
7 empty 1.63 54.5 6.3 No No
8 empty 2.08 73.2 5.7 No No
9 empty 3.02 56.2 6 No No
10 empty 3.08 50 5.5 No No
1Y77_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 60.5 21.9 No No
2 empty 1.46 62.6 14.9 No No
3 empty 1.58 54.3 11 No No
4 empty 2.92 54.9 10.1 No No
5 empty 2.52 69.4 8.4 No No
6 empty 2.83 62.6 8.6 No No
7 empty 1.62 67 6.3 No No
8 empty 2.87 47.9 6.6 No No
9 empty 1.32 69.8 5.9 No No
10 empty 1.64 55.4 5.4 No No
1R9T_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 58.6 20.1 No No
2 empty 1.42 59.6 12.8 No No
3 empty 1.83 58.3 10.7 No No
4 empty 1.56 63.2 8.3 No No
5 empty 2.24 53.9 7.7 No No
6 empty 2.68 54.5 6.5 No No
7 empty 1.37 66.7 6.4 No No
8 empty 3 82.7 0 No No
9 empty 1.42 65 6.1 No No
10 empty 1.24 62.1 5.9 No No
3GTL_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 58.7 22 No No
2 empty 1.35 59.9 12.8 No No
3 empty 1.72 50.9 8.6 No No
4 empty 1.66 67.9 6.7 No No
5 empty 3.02 65.8 8.4 No No
6 empty 2.66 47.7 9.3 No No
7 empty 1.64 70.2 7 No No
8 empty 2.25 59.8 6.2 No No
9 empty 3.6 52.1 6.5 No No
10 empty 3.09 64.9 5.8 No No
4X67_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 56 20.6 No No
2 empty 1.02 59.8 12.5 No No
3 empty 1.84 59.5 10.6 No No
4 empty 1.94 57.1 11.2 No No
5 empty 1.86 53.5 10.8 No No
6 empty 1.36 63 6.7 No No
7 empty 3.6 47.3 6.4 No No
8 empty 3.1 58.3 6.6 No No
9 empty 1.19 62.3 5.2 No No
10 empty 3.36 53.6 5.5 No No
2JA8_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 59.1 18.3 No No
2 empty 1.39 59.3 14.6 No No
3 empty 1.94 66.2 12.5 No No
4 empty 1.68 54.8 9.9 No No
5 empty 2.88 53.2 9.9 No No
6 empty 2.69 78 7.5 No No
7 empty 1.6 62.6 6.3 No No
8 empty 3.28 52.2 6.2 No No
9 empty 2.98 43.9 6.1 No No
10 empty 1.42 71.4 5.8 No No
1SFO_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 55.9 21.5 No No
2 empty 1.27 60.6 12.8 No No
3 empty 1.64 54.9 10.2 No No
4 empty 1.81 65.4 8.3 No No
5 empty 1.5 64.2 6.8 No No
6 empty 2.56 58.7 6.8 No No
7 empty 2.74 83.3 0 No No
8 empty 3.55 43.2 6.9 No No
9 empty 2.85 60.7 7.4 No No
10 empty 1.13 64.1 6 No No
2YU9_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.72 60.5 15 No No
2 empty 1.37 62.2 12.8 No No
3 empty 2.03 52.8 12.1 No No
4 empty 1.66 54.3 10.8 No No
5 empty 1.8 56.4 10 No No
6 empty 2.59 56.6 9.9 No No
7 empty 2.57 74.1 7 No No
8 empty 3.05 59.6 6.5 No No
9 empty 2.57 60.6 0 No No
10 empty 1.46 68 6.8 No No
5FJA_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 64.7 23.7 No No
2 empty 1.48 62.1 18.2 No No
3 empty 2.54 51.9 10.9 No No
4 empty 2.25 73.9 7.2 No No
5 empty 2.16 61.7 8.5 No No
6 empty 1.51 75.6 6.7 No No
7 empty 1.51 57.7 6.6 No No
8 empty 3.27 63 6.1 No No
9 empty 3.14 67.1 5.7 No No
10 empty 1.06 60 5 No No
6I84_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 58.4 23.2 No No
2 empty 1.65 66.4 10.7 No No
3 empty .89 57.6 11.8 No No
4 empty 1.9 56.3 9.2 No No
5 empty 1.84 60.6 8 No No
6 empty 1.66 64.7 8.6 No No
7 empty 2.21 46.3 6.2 No No
8 empty 2.3 61.1 8.6 No No
9 empty 2.07 61.8 6.4 No No
10 empty .75 65.1 5.6 No No
3S14_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 56.8 22.6 No No
2 empty 1.58 65.3 11.4 No No
3 empty 1.75 63.3 9.1 No No
4 empty 1.89 57.1 11.2 No No
5 empty 3.21 64.1 8.1 No No
6 empty 2.99 55.5 6.8 No No
7 empty 1.99 61.7 7.6 No No
8 empty 1.34 55.9 6.5 No No
9 empty 3.3 46.2 7.9 No No
10 empty 1.46 59.2 5 No No
3HOZ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 61.6 18.8 No No
2 empty 1.47 64.6 12.8 No No
3 empty 1.51 51.7 11.8 No No
4 empty 1.85 59.9 8.5 No No
5 empty 2.95 63.4 10.3 No No
6 empty 1.45 63.8 5.8 No No
7 empty 2.11 56.3 9 No No
8 empty 3.26 65.4 5.2 No No
9 empty 2.12 53.2 5.5 No No
10 empty 1.93 63 6 No No
5FYW_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 57.9 22.1 No No
2 empty 1.74 61.4 14.3 No No
3 empty 1.76 51.2 10.7 No No
4 empty 2.36 57.2 8.9 No No
5 empty 2.52 54.8 10.9 No No
6 empty 1.88 50.4 7.5 No No
7 empty 1.56 63.4 6.3 No No
8 empty 2.61 76.3 3.8 No No
9 empty 2.49 54 6.1 No No
5N5Y_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 57.2 18.4 No No
2 empty 1.71 58.5 19.6 No No
3 empty 1.81 65 12.1 No No
4 empty 1.79 61.7 8.2 No No
5 empty 2.44 58.8 10.4 No No
6 empty 3.05 54.5 9.4 No No
7 empty 2.57 51.9 8.4 No No
8 empty 1.98 63 8.6 No No
9 empty 2.55 67.8 8.5 No No
10 empty 1.57 57.3 5 No No
2NVQ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 55.5 19.8 No No
2 empty 1.3 62.2 12.7 No No
3 empty 1.79 61.7 9.8 No No
4 empty 2.01 55.5 10.7 No No
5 empty 3.22 68 6.6 No No
6 empty 2.55 61.8 0 No No
7 empty 2.08 60 7.1 No No
8 empty 1.2 57.3 5.3 No No
9 empty 2.7 52 7.8 No No
10 empty 3.15 63.1 6.1 No No
3S1M_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 59 21.3 No No
2 empty 1.48 62.7 14.9 No No
3 empty 1.98 58.9 10.4 No No
4 empty 2.77 63.3 8.1 No No
5 empty 1.83 54.3 8.3 No No
6 empty 2.42 53.8 7.8 No No
7 empty 2.74 60.6 6.9 No No
8 empty 1.3 60.3 4.9 No No
9 empty 2.26 61.9 4.6 No No
10 empty 1.74 69.9 5 No No
1TWH_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 63.6 19 No No
2 empty 1.61 63.5 13.4 No No
3 empty 1.98 66.3 7.1 No No
4 empty 2.77 52.6 12.7 No No
5 empty 2.59 56.7 9.3 No No
6 empty 1.3 55.5 7.1 No No
7 empty 2.07 48.7 9.1 No No
8 empty 1.38 62.1 6.8 No No
9 empty 2.58 73 7.7 No No
10 empty 3.3 53 5.1 No No
3FKI_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 64 16.4 No No
2 empty 1.94 59.3 17.4 No No
3 empty 1.69 53.7 12.3 No No
4 empty 1.5 63.1 12.3 No No
5 empty 2.35 75.2 7.8 No No
6 empty 2.88 50 8.7 No No
7 empty 3.41 42.2 7.6 No No
8 empty 2.97 57.6 6.3 No No
9 empty 1.98 55.9 6.9 No No
10 empty 1.74 69.8 5.4 No No
3K7A_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 57.8 20.3 No No
2 empty 1.37 62.9 12.1 No No
3 empty 1.82 61 8.9 No No
4 empty 1.9 50.3 9.6 No No
5 empty 2.46 56.7 10.6 No No
6 empty 2.96 54 6 No No
7 empty 1.79 58.9 7.8 No No
8 empty 3.13 37.4 6.6 No No
9 empty 1.57 70.3 0 No No
10 empty 1.27 53.2 4 No No
6HLR_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 55.5 19.3 No No
2 empty 2.15 59.6 18 No No
3 empty 1.7 62.3 12.8 No No
4 empty 2.86 57 8.2 No No
5 empty 1.99 58.6 7.3 No No
6 empty 2.14 55.7 10.7 No No
7 empty 1.96 63.7 5.6 No No
8 empty 2.92 87.6 0 Yes No
9 empty 1.71 71.1 4.2 No No
10 empty 1.14 57.1 7 No No
6H68_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 59.5 21.7 No No
2 empty 2.74 66.5 13.9 No No
3 empty 2.16 60.8 11.8 No No
4 empty 1.54 66 12.8 No No
5 empty 1.62 52.4 11.9 No No
6 empty 2.72 49.6 8.1 No No
7 empty 2.86 67.1 8.8 No No
8 empty 2.16 51.3 7.3 No No
9 empty 2.62 79.5 7.1 No No
10 empty 2.38 74.2 5 No No
1TWG_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 60.7 18.2 No No
2 empty 1.63 62.4 12.6 No No
3 empty 1.86 66 9 No No
4 empty 2.54 55.8 7.1 No No
5 empty 1.35 50.9 5.9 No No
6 empty 1.82 60.2 7.6 No No
7 empty 1.85 54.2 8 No No
8 empty 2.82 75.5 7.3 No No
9 empty 3.66 53.8 6.2 No No
10 empty 2.08 51.5 5.4 No No
2E2I_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 59.6 21.7 No No
2 empty 1.42 61.9 12.4 No No
3 empty 1.68 52.2 10.3 No No
4 empty 1.93 55.8 10.8 No No
5 empty 2.84 51.4 9.8 No No
6 empty 1.91 68.4 5.3 No No
7 empty 1.62 63.2 5.6 No No
8 empty 3.85 49.5 6.6 No No
9 empty 2.76 59.8 5.8 No No
10 empty 2.55 64.8 3.8 No No
4C3I_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 54.2 20.5 No No
2 empty 2.17 56.6 19 No No
3 empty 1.74 61.9 13.8 No No
4 empty 1.84 58.6 9 No No
5 empty 2.67 72.9 7.3 No No
6 empty 2.26 61.4 8.4 No No
7 empty 1.02 56.3 7 No No
8 empty 3.15 59.8 5.5 No No
9 empty 2.13 73.5 5.6 No No
10 empty 3.18 54.4 4.7 No No
6CNC_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 62.9 21.3 No No
2 empty 1.41 61.2 17.1 No No
3 empty 1.38 52.4 8.2 No No
4 empty 2.44 47 8.8 No No
5 empty 2.58 68.8 9.8 No No
6 empty 1.76 67.4 5.4 No No
7 empty 2.91 68.2 4.7 No No
8 empty 3.62 73.7 4.5 No No
9 empty 2.55 54.7 5.9 No No
10 empty 1.77 52.3 6.3 No No
4C3H_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 54.7 21.1 No No
2 empty 2.18 57.4 18.8 No No
3 empty 1.82 67.2 10.6 No No
4 empty 1.79 64.1 9.5 No No
5 empty 2.59 69.9 10.4 No No
6 empty 2.32 60.8 7 No No
7 empty 1.58 59.8 5.1 No No
8 empty 2.05 75.2 4.9 No No
9 empty 2.51 61.8 8 No No
10 empty 3.06 55.4 5.5 No No
6H67_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 57.3 19.5 No No
2 empty 2.21 54.8 22.4 No No
3 empty 1.67 61.9 12.5 No No
4 empty 1.9 64.6 6.9 No No
5 empty 2.6 54 8.5 No No
6 empty 3.16 57 6.8 No No
7 empty 1.21 53.5 6.3 No No
8 empty 2.14 57.9 7.8 No No
9 empty 3.33 84.4 0 Yes No
10 empty 2.37 46 7.1 No No
1R9S_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 60.3 21.9 No No
2 empty 1.39 63 15.1 No No
3 empty 1.89 50.7 10.1 No No
4 empty 2.99 55.6 9.2 No No
5 empty 2.82 53 8 No No
6 empty 3.41 58.5 7.5 No No
7 empty 1.95 53.1 7.6 No No
8 empty 2.64 53.5 5.9 No No
9 empty 3.11 39.2 6.4 No No
5M5Y_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.02 56.3 21.4 No No
2 empty 2.37 54.4 17.6 No No
3 empty 1.56 65.6 13.9 No No
4 empty 2.13 62.7 7.2 No No
5 empty 2.59 57.3 7.3 No No
6 empty 2.44 56.3 9 No No
7 empty 1.91 61.5 5.8 No No
1Y1W_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 62.3 21.5 No No
2 empty 1.42 61.1 13.5 No No
3 empty 1.62 55.8 9.8 No No
4 empty 2.88 56.6 9.6 No No
5 empty 2.64 77.2 7.3 No No
6 empty 1.35 61.8 5.8 No No
7 empty 3.22 60 6.3 No No
8 empty 1.96 50 6.3 No No
9 empty 1.25 65.6 5.9 No No
10 empty 2.79 45.4 6.3 No No
3H3V_K DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 55.1 20.2 No No
2 empty 1.44 59.3 11.8 No No
3 empty 1.58 64.6 9.4 No No
4 empty 1.72 56.4 10 No No
5 empty 1.95 60.1 8.7 No No
6 empty 2.52 59.9 13.1 No No
7 empty 2.16 60 8.1 No No
8 empty 2.52 75.2 7.6 No No
9 empty 2.46 61.3 7.4 No No
10 empty 3.22 56 8.9 No No
2B63_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 60.7 21.3 No No
2 empty 1.44 63.6 13.3 No No
3 empty 1.76 56.5 10.7 No No
4 empty 2.9 59.5 9.7 No No
5 empty 2.65 52.1 8.5 No No
6 empty 2.47 58.9 8 No No
7 empty 2.79 59.5 9.2 No No
8 empty 3.03 67.1 5.9 No No
9 empty 1.44 52.6 5 No No
10 empty 1.91 61.6 5.1 No No
2NVX_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 54.9 26.6 Yes No
2 empty 1.47 60.6 13.7 No No
3 empty 1.92 60 10.6 No No
4 empty 2.13 58 10.2 No No
5 empty 2.36 64 10.3 No No
6 empty 3.01 63.2 8 No No
7 empty 3.75 49 6.8 No No
8 empty 2.96 61.1 7.1 No No
9 empty 2.79 63 5.9 No No
10 empty 1.69 66.7 5.7 No No
5N5Z_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.31 54.4 18.4 No No
2 empty 1.85 59.5 21.4 No No
3 empty 1.76 58.7 12.6 No No
4 empty 1.89 59.3 8 No No
5 empty 2.46 51.7 9.1 No No
6 empty 2.27 66.9 0 No No
7 empty 2.64 69.2 7.2 No No
8 empty 2.41 52.3 7.6 No No
9 empty 2.04 71.3 5.2 No No
10 empty 1.54 64.8 5.7 No No
4A3B_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 59.3 21.7 No No
2 empty 1.63 62.2 14.1 No No
3 empty 1.81 54.1 10.1 No No
4 empty 2.06 56 9.7 No No
5 empty 2.36 75.7 7.1 No No
6 empty 2.84 63.8 6.4 No No
7 empty 1.27 60.6 7.2 No No
8 empty 3.12 60.6 5.7 No No
9 empty 3.08 50.8 4.9 No No
10 empty 3.81 51.5 4.8 No No
3I4M_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 58.7 21.9 No No
2 empty 1.43 61.6 14.8 No No
3 empty 1.74 50 10.6 No No
4 empty 2.92 58.4 10 No No
5 empty 2.93 57 6 No No
6 empty 1.56 61.9 5.7 No No
7 empty 3.27 67.6 0 No No
8 empty 1.72 55.1 6.4 No No
9 empty 1.97 63 5.8 No No
10 empty 3.22 43.7 5.7 No No
6F42_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.91 57.1 20.8 No No
2 empty 1.68 56.7 14 No No
3 empty 1.34 51.7 11.5 No No
4 empty 2.52 49 9.3 No No
5 empty 1.7 74.1 6.2 No No
6 empty 2.8 61.7 5.3 No No
7 empty 2.93 61 7.1 No No
8 empty 2.68 47.9 6.8 No No
9 empty 1.84 82.1 0 No No
10 empty 2.9 67.1 5.9 No No
5FZ5_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 57.9 21.8 No No
2 empty 1.74 61.7 11.5 No No
3 empty 1.84 54.2 10.1 No No
4 empty 2.4 57 8.2 No No
5 empty 2.12 52 7.7 No No
6 empty 1.39 65 5.8 No No
7 empty 2.73 52.3 8.6 No No
8 empty 3.21 62.5 6 No No
9 empty 2.83 67.4 6.2 No No
10 empty 2.8 69.2 4 No No
1K83_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 61.3 17.5 No No
2 empty 1.54 68.7 11 No No
3 empty 1.78 54.4 9.2 No No
4 empty 1.77 58.9 8.2 No No
5 empty 1.64 56.7 7.7 No No
6 empty 2.5 77 7.6 No No
7 empty 2.03 49.2 7.9 No No
8 empty 3.73 48.6 6.6 No No
9 empty 2.71 59.2 7.7 No No
4V1N_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 57.2 21.7 No No
2 empty 1.77 65.8 11 No No
3 empty 1.68 55.1 9.9 No No
4 empty 1.59 64.6 8.6 No No
5 empty 2.2 80.2 6 No No
6 empty 1.95 52.2 7.5 No No
7 empty 2.65 56.9 8 No No
8 empty 3.61 44.8 7.3 No No
9 empty 2.98 58.4 7.1 No No
10 empty 2.5 54.7 5.8 No No
6HLQ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.22 57.3 18.8 No No
2 empty 2.09 59.3 18.1 No No
3 empty 1.71 64.1 14.5 No No
4 empty 1.85 60.6 7.2 No No
5 empty 2.9 61.5 10 No No
6 empty 2.11 56.6 11 No No
7 empty 1.83 63.6 6.7 No No
8 empty 2.91 62.7 5.6 No No
9 empty 1.64 71.4 4.9 No No
10 empty 2.96 87.3 0 Yes No
2R7Z_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 61.2 22.4 No No
2 empty 1.37 62 11.3 No No
3 empty 1.88 50.6 10.5 No No
4 empty 2.85 58.6 9.6 No No
5 empty 2.59 66.9 7.3 No No
6 empty 2.67 55.8 6.8 No No
7 empty 2.48 59.7 7.8 No No
8 empty 2.04 53.1 5.5 No No
9 empty 3.2 54.5 5.3 No No
10 empty 1.7 59 4.6 No No
3RZO_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 61 23 No No
2 empty 1.5 61.6 13.8 No No
3 empty 1.84 60.6 11 No No
4 empty 1.68 58.3 11.7 No No
5 empty 2.66 56.1 8 No No
6 empty 2.97 63.9 7.8 No No
7 empty 2.16 59.7 7.7 No No
8 empty 2.86 56.5 8.1 No No
9 empty 3.78 49.4 5.4 No No
1NIK_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 57.3 20 No No
2 empty 1.14 67.4 11.9 No No
3 empty 1.9 66 9.3 No No
4 empty 1.78 48.6 9.3 No No
5 empty 1.81 60.2 8.4 No No
6 empty 2.76 63 7 No No
7 empty 3.43 57.8 7.1 No No
8 empty 2.81 50.8 6.7 No No
9 empty 1.17 52.1 5.5 No No
10 empty 2.8 50.5 4.8 No No
3QT1_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 59.3 23 No No
2 empty 1.45 62.3 12.5 No No
3 empty 1.58 55.3 11.1 No No
4 empty 2.71 59.8 9.4 No No
5 empty 1.75 86.5 0 Yes No
6 empty 2.16 51.6 7.7 No No
7 empty 1.9 48.2 8 No No
8 empty 2.39 66.2 6.1 No No
9 empty 1.69 65.9 5.6 No No
10 empty 3 55.9 5.7 No No
5OQJ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 57 22.5 No No
2 empty 1.77 63.1 10.9 No No
3 empty 1.74 52.4 8.8 No No
4 empty 2.71 67.8 7.2 No No
5 empty 2.23 51.3 8.3 No No
6 empty 1.63 52.8 6.7 No No
7 empty 3.2 57.5 6.1 No No
8 empty 2.96 63.5 5.9 No No
9 empty 3.6 46.7 5.3 No No
10 empty 3.61 60 5.2 No No
2B8K_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 59.1 20.1 No No
2 empty 1.45 61 11.6 No No
3 empty 1.59 53.1 10.3 No No
4 empty 1.66 66.2 9.5 No No
5 empty 2.84 56.3 9.4 No No
6 empty 2.58 74.8 8.1 No No
7 empty 2.85 57.9 6.6 No No
8 empty 2.92 56.4 6.7 No No
9 empty 1.56 64.6 5.3 No No
10 empty 1.99 56.2 5.3 No No
4A93_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 59.8 21.3 No No
2 empty 1.72 59 13.6 No No
3 empty 1.53 55.3 10.4 No No
4 empty 1.48 58 8.1 No No
5 empty 1.81 61.5 6.6 No No
6 empty 3.18 58.7 6 No No
7 empty 2.69 55.7 6.1 No No
8 empty 2.05 48.9 6.8 No No
9 empty 3.11 57.5 4.9 No No
10 empty .32 55.1 4.6 No No
5C4J_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 61 20.1 No No
2 empty 1.76 51.9 13.3 No No
3 empty 2.64 63.7 12.9 No No
4 empty 2.04 57.8 8.1 No No
5 empty 1.14 50.3 10.6 No No
6 empty 2.09 67.8 7.2 No No
7 empty 2.44 68.2 7.5 No No
8 empty 2.86 59.7 6.1 No No
9 empty 2.21 58.4 6.6 No No
10 empty 1.38 61.3 5.5 No No
1I3Q_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 61.9 20.4 No No
2 empty 1.42 59.4 15.3 No No
3 empty 1.76 56 9.2 No No
4 empty 1.57 62.4 7.2 No No
5 empty 1.59 58.6 7.2 No No
6 empty 2.9 75.9 7.3 No No
7 empty 2.35 50 8.1 No No
8 empty 2.68 54.5 6.5 No No
9 empty 3.51 44.6 5.5 No No
10 empty 2.68 52.5 6.9 No No
3S1N_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 59.8 19.1 No No
2 empty 1.35 61.2 16.5 No No
3 empty 1.68 57.4 11 No No
4 empty 1.92 61.1 7.3 No No
5 empty 2.15 54.5 8.3 No No
6 empty 2.91 58.9 7 No No
7 empty 3.39 67.7 6.5 No No
8 empty 3.4 40.8 6.7 No No
4BBS_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.05 61.3 20.7 No No
2 empty 1.46 64.6 13.6 No No
3 empty 1.83 59.2 9.9 No No
4 empty 2.25 50.8 12 No No
5 empty 2.72 58.6 11 No No
6 empty 3.03 63.3 5.9 No No
7 empty 2.49 59.8 6.6 No No
8 empty 2.02 58 6.9 No No
9 empty 3.52 53.8 5.2 No No
3GTJ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 54.3 21.7 No No
2 empty 1.63 61.9 13 No No
3 empty 1.8 60.4 10.5 No No
4 empty 1.56 46.7 10.8 No No
5 empty 1.67 64 6.9 No No
6 empty 2.9 60.4 7.5 No No
7 empty 3.64 43.4 7.2 No No
8 empty 2.73 64.5 6.8 No No
9 empty 2.4 73.9 5.1 No No
10 empty 2.44 58.6 7.2 No No
3HOW_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 61.4 21.6 No No
2 empty 1.48 62.2 14.6 No No
3 empty 1.8 49.8 11.4 No No
4 empty 1.52 64.3 6.6 No No
5 empty 3.06 54.8 6.4 No No
6 empty 2.55 57.5 6.7 No No
7 empty 1.79 54.5 7.9 No No
8 empty 1.62 53.6 7.5 No No
9 empty 2.64 73.7 6.1 No No
10 empty 2.67 68.5 5.5 No No
1I6H_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.05 60 22.5 No No
2 empty 1.36 62.5 12.5 No No
3 empty 1.75 57.6 8.3 No No
4 empty 2.14 52.8 9.6 No No
5 empty 2.27 56.1 11.8 No No
6 empty 3.29 61.5 7.9 No No
7 empty 1.32 55.4 7.3 No No
8 empty 3.44 58.1 6.9 No No
9 empty 2.94 81.2 0 No No
10 empty 3.11 44.4 5.9 No No
6HLS_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.51 55.3 19.1 No No
2 empty 2.04 58 19 No No
3 empty 1.67 65.7 13.6 No No
4 empty 1.86 58.7 8.6 No No
5 empty 2.92 56.4 8.4 No No
6 empty 2.3 58.9 8.6 No No
7 empty 1.92 63.2 6.5 No No
8 empty 2.87 82.4 0 No No
9 empty 1.23 60 5.3 No No
10 empty 1.01 65.7 4.8 No No
2VUM_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 59.1 17.4 No No
2 empty 1.46 63.6 13.6 No No
3 empty 2.06 62.7 13.1 No No
4 empty 1.76 51.3 10.5 No No
5 empty 2.23 60.7 9.3 No No
6 empty 2.71 54.5 5.8 No No
7 empty 2.75 60.5 6.2 No No
8 empty 3.43 66.7 7.1 No No
9 empty 2.45 53.1 7.1 No No
10 empty 2.66 64.9 6 No No
3I4N_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 59.4 17.6 No No
2 empty 1.43 62.2 12.3 No No
3 empty 1.86 53.3 10.3 No No
4 empty 1.83 65.3 7.8 No No
5 empty 2.1 53 7.9 No No
6 empty 1.51 63.1 6.9 No No
7 empty 3.15 63.4 6.3 No No
8 empty 2.7 53.6 5.9 No No
9 empty 2.76 51 5.4 No No
10 empty 2.5 78.1 5.6 No No
4A3E_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 58.1 21.4 No No
2 empty 1.73 59.9 12.5 No No
3 empty 1.66 54.8 10.2 No No
4 empty 2.04 58.2 10.1 No No
5 empty 1.77 72.8 7.3 No No
6 empty 3.42 47.2 6.5 No No
7 empty 2.94 62.3 5.2 No No
8 empty 3.16 63.3 6.2 No No
9 empty 2.57 50.7 5.5 No No
10 empty 3.14 56.9 6.1 No No
5IP7_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 60.1 24.2 Yes No
2 empty 1.75 60.7 11.3 No No
3 empty 1.52 51.2 10.3 No No
4 empty 2.02 61.5 7.6 No No
5 empty 2.43 52.9 7.3 No No
6 empty 3.02 62.3 7.2 No No
7 empty 2.6 52.9 5.7 No No
8 empty 3.93 48.2 4.7 No No
6GYK_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 58.4 22.5 No No
2 empty 1.75 63.6 11.7 No No
3 empty 1.43 52.4 9.4 No No
4 empty 3.01 56.8 7.6 No No
5 empty 3.2 62.4 6.3 No No
6 empty 1.62 54.5 6.2 No No
7 empty 3.25 57.1 8.6 No No
8 empty 2.97 60.2 5.2 No No
9 empty 2.7 84.8 3.7 Yes No
10 empty 1.55 64.8 7 No No
5W65_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 57.2 19 No No
2 empty 2.62 61 15.8 No No
3 empty 1.67 60.7 11.2 No No
4 empty 1.28 55 11.6 No No
5 empty 1.95 58.1 9.5 No No
6 empty 2.19 65.1 8 No No
7 empty 3.29 71 6.1 No No
8 empty 2.48 49.5 7.2 No No
9 empty 2.82 75.5 0 No No
10 empty 1.78 64.2 7.3 No No
3HOV_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.14 57.1 21.1 No No
2 empty 1.42 63.5 11.5 No No
3 empty 1.83 52.1 11.3 No No
4 empty 2.82 57.1 9.7 No No
5 empty 1.91 60.9 8.8 No No
6 empty 2.74 50.4 8.5 No No
7 empty 1.47 64.3 7.6 No No
8 empty 3.46 57.5 5.9 No No
9 empty 3.55 41 5.5 No No
6EU3_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 58.4 23.2 No No
2 empty 1.51 63.6 15.7 No No
3 empty 1.39 56.6 12.8 No No
4 empty 1.91 68.4 9.8 No No
5 empty 2.15 63.6 9.5 No No
6 empty 2.5 60.3 8.3 No No
7 empty 2.37 58.5 9.2 No No
8 empty 2.7 52.9 8 No No
9 empty 2.53 63.5 5.2 No No
10 empty 2.23 57.1 5.3 No No
6BM4_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 58.1 21.6 No No
2 empty 1.34 62.8 18.3 No No
3 empty 1.6 51.1 11.5 No No
4 empty 1.72 60.8 8.4 No No
5 empty 1.97 61.3 6.8 No No
6 empty 2.27 63.3 4.9 No No
7 empty 3.72 52.1 6.3 No No
8 empty 1.67 64.4 5.1 No No
9 empty 2.37 54.8 6.2 No No
3S1R_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 58.3 22.4 No No
2 empty 1.53 61.4 12.3 No No
3 empty 1.85 57.7 10.9 No No
4 empty 2.19 56.8 7.2 No No
5 empty 2.82 56.8 7.8 No No
6 empty 2.8 51.9 7.1 No No
7 empty 3.17 57.7 6 No No
8 empty 1 60 6.9 No No
9 empty 3.47 48 8.5 No No
10 empty 3.09 66.2 4.8 No No
6BLO_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 57.9 20.8 No No
2 empty 1.29 62.3 18.3 No No
3 empty 1.66 52.2 11.7 No No
4 empty 1.8 63.2 9.1 No No
5 empty 1.88 65.9 6.6 No No
6 empty .77 64.7 4.9 No No
7 empty 2.1 58.1 7.1 No No
8 empty 3.7 54.5 6.2 No No
5M64_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 59.2 17.9 No No
2 empty 2.54 56.5 17.2 No No
3 empty 1.94 64.1 9.8 No No
4 empty 1.98 69.8 8.8 No No
5 empty 1.11 55.1 7.9 No No
6 empty 1.97 63.5 6.4 No No
7 empty 1.64 55.4 7.1 No No
8 empty 2.64 58 7.6 No No
9 empty 2.36 57.1 8.9 No No
10 empty 1.08 61.2 4.9 No No
6CND_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.9 63.1 21.9 No No
2 empty 1.3 58.2 14.7 No No
3 empty .98 59.5 8.5 No No
4 empty 2.57 66.7 8.7 No No
5 empty 2.62 46.7 7.9 No No
6 empty 1.49 64.2 6.2 No No
7 empty 2.02 54.3 6.1 No No
8 empty 1.7 64.4 6.1 No No
9 empty 2.71 67.9 5.1 No No
10 empty 2.77 66.7 6 No No
2JA7_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 56.7 20.4 No No
2 empty 1.47 62.9 13.3 No No
3 empty 2.02 64.6 12 No No
4 empty 1.61 51.2 10.7 No No
5 empty 2.85 56 9 No No
6 empty 2.55 70.9 8.4 No No
7 empty 2.69 54.8 5.8 No No
8 empty 2.04 63 6.2 No No
9 empty 3.24 59.2 6.2 No No
10 empty 1.09 71.6 5.4 No No
6BQF_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 56.5 20.4 No No
2 empty 1.24 60.5 15.2 No No
3 empty 1.58 52.8 11.6 No No
4 empty 1.75 65 9.7 No No
5 empty 2.18 61.3 5.5 No No
6 empty 2.34 63.3 5 No No
7 empty .74 62.5 0 No No
1TWF_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 59.7 20.9 No No
2 empty 1.58 64.8 11.9 No No
3 empty 1.57 52 10.6 No No
4 empty 1.65 51.8 6.7 No No
5 empty 2.52 79.7 6.8 No No
6 empty 2.71 52 6.7 No No
7 empty 3.65 53.8 6.4 No No
8 empty 2.2 47.6 8.6 No No
9 empty 1.45 65.3 6.4 No No
10 empty 2.48 50.5 6.2 No No
6F40_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.1 59.3 23.4 No No
2 empty 1.65 65 13.5 No No
3 empty 2.47 48.2 9.2 No No
4 empty 1.55 57.8 8.9 No No
5 empty 2.52 55.1 9.2 No No
6 empty 1.35 56.6 9 No No
7 empty 2.91 61 8.2 No No
8 empty 1.93 56.8 8.3 No No
9 empty 2.59 55.4 6.5 No No
10 empty 2.3 55.7 7.9 No No
4BXZ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 63.2 18.4 No No
2 empty 1.69 59.8 12.9 No No
3 empty 1.61 58.2 10.8 No No
4 empty 1.97 57.8 9.9 No No
5 empty 2.26 63.6 8.7 No No
6 empty 2.52 54.8 7.4 No No
7 empty 1.97 59.7 6.2 No No
8 empty 3.51 57.1 4.7 No No
9 empty 1.01 62.4 4.9 No No
10 empty 2.51 47.4 5.4 No No
3HOY_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.06 56.9 20.5 No No
2 empty 1.39 62.4 12.6 No No
3 empty 1.87 53.1 10.2 No No
4 empty 1.69 62.8 8.5 No No
5 empty 2.73 51.4 10 No No
6 empty 2.84 55.9 10 No No
7 empty 1.97 64.8 8.7 No No
8 empty 3.25 61 6.6 No No
9 empty 2.04 57.9 7.8 No No
10 empty 2.07 57.7 8.7 No No
5SVA_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.96 59.1 19.7 No No
2 empty 1.69 62.1 14.6 No No
3 empty 1.67 56.3 9.8 No No
4 empty 2.01 62.3 9.4 No No
5 empty 1.89 60 7.9 No No
6 empty 2.11 76.5 6.8 No No
7 empty 2.67 59.7 8.2 No No
8 empty 3.41 36.1 6.8 No No
9 empty 2.47 50.6 6.2 No No
10 empty 1.67 76.6 0 No No
5W51_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 57.4 19.4 No No
2 empty 1.36 59.4 12.3 No No
3 empty 1.78 61.2 11 No No
4 empty 1.61 51.4 11.7 No No
5 empty 1.11 63 6.4 No No
6 empty 2 59.2 9.4 No No
7 empty 1.53 51.5 7.4 No No
8 empty 2.23 61.2 5.3 No No
9 empty 3.13 59.3 5.2 No No
10 empty .78 60.3 5.4 No No
6BM2_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 57.1 20.9 No No
2 empty 1.3 60.4 17.4 No No
3 empty 1.61 52.7 11 No No
4 empty 1.68 63.3 8.1 No No
5 empty 1.85 61.1 6.6 No No
6 empty 2.71 61.3 5.9 No No
7 empty .8 67.6 5.2 No No
8 empty 2.64 59.3 9.2 No No
9 empty 3.87 51.2 5.7 No No
3RZD_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 56.8 24.3 Yes No
2 empty 1.62 65 12 No No
3 empty 1.77 53.9 10.3 No No
4 empty 1.87 62.2 10 No No
5 empty 2.09 59.2 7.6 No No
6 empty 2.48 57.5 11.2 No No
7 empty 1.29 59.7 7.7 No No
8 empty 3.51 66.7 6.8 No No
9 empty 3.17 48.8 6.6 No No
10 empty 2.34 56.5 7.5 No No
5W64_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2 56.3 18.8 No No
2 empty 2.6 58.6 16.1 No No
3 empty 1.7 65 12.1 No No
4 empty 1.07 52.7 12.4 No No
5 empty 1.88 62 9.3 No No
6 empty 2.27 56.8 7.4 No No
7 empty 2.79 68.9 4.9 No No
8 empty .9 57.5 6.2 No No
9 empty 2.54 70.2 5.6 No No
10 empty 2.53 53.7 5.5 No No
3GTQ_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.25 59.3 22.8 No No
2 empty 1.46 63.3 13.3 No No
3 empty 1.5 53.4 10.2 No No
4 empty 2.41 62.3 12.5 No No
5 empty 2.1 64 10.1 No No
6 empty 2.82 53.4 10.4 No No
7 empty 3.46 60.6 7.7 No No
8 empty 3.11 51.3 8.4 No No
9 empty 1.37 69.1 5.3 No No
10 empty 3.75 46.4 7.3 No No
3J1N_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.99 70.9 28 Yes Yes
2 empty 1.54 66.7 10.7 No No
3 empty 1.63 64.9 11.3 No No
4 empty 2.08 47.3 8.6 No No
3PO2_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 59.4 18.7 No No
2 empty 1.76 59.5 13.3 No No
3 empty 1.97 57 10 No No
4 empty 1.82 54.3 10.8 No No
5 empty 2 55.5 7.7 No No
6 empty 2.95 49.5 5.7 No No
7 empty 1.99 66.1 6.5 No No
8 empty 3.07 61.6 6.5 No No
9 empty 3.82 45.6 6.5 No No
6EU0_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.88 66.2 17.4 No No
2 empty 1.24 58.3 17 No No
3 empty 1.83 72.2 16.8 No No
4 empty 2.48 43.8 8.7 No No
5 empty 2.43 46.9 13.6 No No
6 empty 2.43 57.9 7.3 No No
7 empty 2.98 68.5 6.2 No No
8 empty 2.34 61.2 7.2 No No
9 empty 1.71 64.8 5.6 No No
10 empty 2.21 57.8 8.9 No No
4X6A_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 56.9 21.4 No No
2 empty 1.37 60.1 12.6 No No
3 empty 1.64 56.8 9.8 No No
4 empty 1.81 61.8 11.2 No No
5 empty 1.92 58.9 6.7 No No
6 empty 1.5 67.6 5.7 No No
7 empty 2.69 51.6 9.2 No No
8 empty 3.75 43.1 6.3 No No
9 empty 1.21 63.2 6.1 No No
10 empty 2.49 64.9 6.5 No No
4C2M_Y DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.3 57 17.6 No No
2 empty 1.82 59.6 19 No No
3 empty 1.79 59.9 13.9 No No
4 empty 1.78 64.9 7.3 No No
5 empty 2.61 54.8 6.6 No No
6 empty 2.87 54.9 6.2 No No
7 empty 2.37 59 9.5 No No
8 empty 2.43 56.1 7.7 No No
9 empty 1.69 58.7 8 No No
10 empty 2.14 67.3 5.1 No No
6CNF_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.75 60.1 17.2 No No
2 empty 1.44 60.4 15.9 No No
3 empty 1.68 60 12.3 No No
4 empty 1.21 56.9 8.2 No No
5 empty 1.98 46.1 14.4 No No
6 empty 2.04 63.9 6.2 No No
7 empty 1.34 49.6 9.2 No No
8 empty 2 96.4 0 Yes No
9 empty 3.03 95.3 0 Yes No
10 empty 3.02 73.5 4.8 No No
6HKO_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.39 54.5 20.6 No No
2 empty 2.07 61.3 18.2 No No
3 empty 1.67 58.4 14.9 No No
4 empty 1.84 61.8 9.9 No No
5 empty 2.89 61.1 7.3 No No
6 empty 2.31 55.5 9.1 No No
7 empty 2.83 63.1 5.5 No No
8 empty 2.88 80.7 0 No No
9 empty 2.01 64.6 6.2 No No
10 empty 1.11 61.1 7 No No
4BY7_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 57 30.8 Yes No
2 empty 1.72 63.5 12.3 No No
3 empty 2.13 57.7 12 No No
4 empty 2.24 68.8 9.1 No No
5 empty 2.6 50 7.9 No No
6 empty 3.6 54.4 5.3 No No
7 empty 2.23 54.5 7 No No
8 empty 3.01 58.3 7.2 No No
9 empty 2.15 58.6 5.2 No No
10 empty 1.3 55.3 5.7 No No
4A3M_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 60.8 18.7 No No
2 empty 1.69 62 12.8 No No
3 empty 1.54 55.6 10.2 No No
4 empty 1.76 57.5 10.5 No No
5 empty 2.38 73.3 8.9 No No
6 empty 2.65 59.5 6.4 No No
7 empty 2.28 59.3 8.4 No No
8 empty 1.97 57.5 6.2 No No
9 empty 1.56 54.4 5.8 No No
10 empty 2.62 61.4 5.8 No No
5VVS_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 55 20.7 No No
2 empty 1.81 63.1 10 No No
3 empty 1.81 60.8 10.2 No No
4 empty 3.14 55.6 13.3 No No
5 empty 1.74 80.8 8.5 No No
6 empty 3.24 60.4 6.8 No No
7 empty 2.43 71.8 4.8 No No
8 empty 3.38 61.8 5.3 No No
9 empty 2.51 54.8 4.8 No No
10 empty 3.27 63.8 5.7 No No
3S15_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 55.8 22.7 No No
2 empty 1.4 60.1 17.5 No No
3 empty 2.1 57.3 12.4 No No
4 empty 2.06 56.1 8.2 No No
5 empty 3.05 62.9 7.5 No No
6 empty 1.84 57.7 7.8 No No
7 empty 2.48 58.7 8.7 No No
8 empty 2.83 58.5 7.1 No No
9 empty 1.74 61.4 6.1 No No
10 empty 1.4 65.2 4.9 No No
1R5U_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 60.1 18.2 No No
2 empty 1.15 64.4 13.3 No No
3 empty 1.91 58.3 8.2 No No
4 empty 1.9 51.4 10.1 No No
5 empty 2.78 62.4 7.3 No No
6 empty 3.29 57.9 7.5 No No
7 empty 1.32 56.1 5.8 No No
8 empty 2.57 52 7.9 No No
9 empty 3.03 81.6 6.8 No No
10 empty 2.82 47.2 6.6 No No
4A3I_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 59.6 23.1 No No
2 empty 1.72 60 15 No No
3 empty 1.51 53.6 9.8 No No
4 empty 1.69 73.3 8.8 No No
5 empty 2.39 55 8.2 No No
6 empty 1.77 65.5 4.9 No No
7 empty 2.53 61.8 5.9 No No
8 empty 2.9 50.7 5.4 No No
2NVT_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.37 57.1 14.7 No No
2 empty 1.76 67 12.5 No No
3 empty 1.35 65.7 12.1 No No
4 empty 1.75 59.8 9.6 No No
5 empty 1.93 53.8 10.8 No No
6 empty 2.95 55.1 9.3 No No
7 empty 2.58 62.3 7.8 No No
8 empty 1.55 65.9 6.6 No No
9 empty 2.83 50 7 No No
10 empty 3.73 35.9 6.1 No No
5C4A_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.98 60.7 22.9 No No
2 empty 1.6 53.1 13.2 No No
3 empty 1.38 64.5 11.6 No No
4 empty 2.3 51.9 7.8 No No
5 empty .95 58.6 6.5 No No
6 empty 1.93 53.1 8.2 No No
7 empty 1.96 92.9 4.9 Yes No
8 empty 2.41 59.1 5.3 No No
9 empty 3.3 59.7 6.3 No No
10 empty 1.71 65.8 5.4 No No
5U5Q_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.2 59 21 No No
2 empty 1.66 61.6 15.3 No No
3 empty 2.09 54.8 10.8 No No
4 empty 2.35 64.7 9 No No
5 empty 1.82 68.7 8.2 No No
6 empty 2.95 57.8 9.6 No No
7 empty 1.64 62.2 6.2 No No
8 empty 1.44 50.5 7.3 No No
9 empty 1.62 63.9 6.4 No No
10 empty 3.36 60 5.7 No No
5N61_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.28 57.2 20.1 No No
2 empty 1.87 55.1 21.5 No No
3 empty 1.74 65.6 12.8 No No
4 empty 1.81 62.4 9.3 No No
5 empty 2.32 68.6 0 No No
6 empty 2.63 50.3 8.8 No No
7 empty 3.13 64.8 7 No No
8 empty 1.48 68.2 6.5 No No
9 empty 2.73 54.2 6.9 No No
10 empty 2.45 72.6 5.2 No No
3S1Q_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.16 59.9 23.7 No No
2 empty 1.54 63.2 12.6 No No
3 empty 1.53 49.7 10 No No
4 empty 2.92 66.9 8.9 No No
5 empty 1.81 55.4 8.7 No No
6 empty 2.89 61 7.6 No No
7 empty 3.56 45.4 6.2 No No
8 empty 3 54.1 7.7 No No
9 empty 2.82 55.1 0 No No
2E2J_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 60.5 21.9 No No
2 empty 1.42 64.7 13.2 No No
3 empty 1.59 53.5 10.1 No No
4 empty 1.76 60.5 9.8 No No
5 empty 1.96 66.7 6 No No
6 empty 3.06 55.7 8 No No
7 empty 2.89 53.7 7.7 No No
8 empty 3.63 47.7 6.7 No No
9 empty 2.76 81.3 0 No No
10 empty 2.34 57.5 6.4 No No
6F44_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.95 60.4 22.6 No No
2 empty 1.47 62.8 16.9 No No
3 empty 2.65 48.9 8.9 No No
4 empty 1.29 55.8 8.3 No No
5 empty 2.23 55.3 9.3 No No
6 empty 2.68 54.5 9.1 No No
7 empty 2.76 61.1 5.8 No No
8 empty 1.73 57.5 8 No No
9 empty 2.75 64.2 6.5 No No
10 empty 2.31 58.4 6 No No
5VVR_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.97 59 26.7 Yes No
2 empty 1.6 65.5 15.2 No No
3 empty 1.82 59.7 16.2 No No
4 empty 2.18 58.9 12.9 No No
5 empty 2.4 58.2 13.7 No No
6 empty 2.23 60.2 14.4 No No
7 empty 2.55 70 7.9 No No
8 empty 2.45 53.7 8.4 No No
9 empty 1.21 73.5 7.2 No No
10 empty 1.44 59.1 6.3 No No
4Y52_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.17 54.9 21.6 No No
2 empty 1.4 59.1 17.2 No No
3 empty 1.76 56.6 8.5 No No
4 empty 1.69 51.3 11.2 No No
5 empty 2.27 59.1 0 No No
6 empty 3.71 47.5 7 No No
7 empty 1.53 72 5 No No
8 empty 2.05 58.9 6.4 No No
9 empty 2.97 67.1 5.7 No No
5M5W_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.2 54.4 17.8 No No
2 empty 2.09 60.6 18.6 No No
3 empty 1.58 61.9 15.3 No No
4 empty 1.82 63.3 8.7 No No
5 empty 2.67 88.1 0 Yes No
6 empty 2.55 53.7 6.1 No No
7 empty 2.55 56 7.6 No No
8 empty 2.79 66.7 6.1 No No
9 empty 1.32 50.6 7.6 No No
10 empty 1.85 65.2 5.5 No No
3HOU_V DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.09 59.7 21.7 No No
2 empty 1.32 61.9 13.9 No No
3 empty 1.6 52.7 9.8 No No
4 empty 2.96 57.7 9.2 No No
5 empty 3.1 58.7 6.5 No No
6 empty 1.49 66.7 7.1 No No
7 empty 2.24 55.1 7.7 No No
8 empty 2.6 50 7.7 No No
9 empty 3.59 49.4 5.5 No No
3HOX_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.11 58.3 19.8 No No
2 empty 1.4 64.3 12.5 No No
3 empty 1.63 51.6 10.2 No No
4 empty 1.86 56.4 8 No No
5 empty 2.81 58.5 11.3 No No
6 empty 2.62 70.5 7.6 No No
7 empty 2.66 59.4 5.9 No No
8 empty 1.47 61.8 7 No No
9 empty 2.73 57 6.7 No No
10 empty 3.31 60.3 5.7 No No
2JA5_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.9 61.4 19.4 No No
2 empty 1.38 61.7 13.4 No No
3 empty 1.96 65.2 13.2 No No
4 empty 1.87 51.8 10.4 No No
5 empty 2.84 50.6 10.5 No No
6 empty 2.69 75 8.4 No No
7 empty 2.13 56.6 10.3 No No
8 empty 2.74 52.7 6.2 No No
9 empty 1.53 67 5.9 No No
10 empty 2.96 48 6.6 No No
4A3L_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.15 60.3 23.9 No No
2 empty 1.63 56.3 10 No No
3 empty 2.42 77.6 6.9 No No
4 empty 2.29 53.6 8.8 No No
5 empty 2.8 56.2 7.8 No No
6 empty 3.4 59.3 5.4 No No
7 empty 1.85 62.6 5.4 No No
8 empty 3.19 58.8 6.3 No No
9 empty 2.76 54.7 5.5 No No
10 empty 2.59 51.5 4.7 No No
5W4U_J DNA-directed RNA polymerases I, II, and III subunit RPABC5 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 58.3 21.6 No No
2 empty 1.22 62.8 16.9 No No
3 empty 1.92 52.9 11.8 No No
4 empty 1.68 55.6 8.7 No No
5 empty 3.07 58 9.6 No No
6 empty 1.56 59.8 6 No No
7 empty 2.42 60.9 5.9 No No
8 empty .84 60.8 5.3 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed78
Domains assessed as druggable using the strict criteria0
Domains assessed as druggable using the relaxed criteria4

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1I3Q_J (61617) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.1Å No No
1I50_J (61764) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 2.8Å No No
1I6H_J (61841) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.3Å No No
1K83_J (68285) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 2.8Å No No
1NIK_J (85752) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 4.1Å No No
1R5U_J (97112) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 4.5Å No No
1R9S_J (111736) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 4.25Å No No
1R9T_J (111746) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 3.5Å No No
1SFO_J (98841) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 3.6Å No No
1TWA_J (112706) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.1Å No No
1TWC_J (112721) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3Å No No
1TWF_J (112735) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 2.3Å No No
1TWG_J (112748) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.3Å No No
1TWH_J (112761) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.4Å No No
1WCM_J (114519) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 3.8Å No No
1Y1V_J (116358) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 3.8Å No No
1Y1W_J (116371) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 4Å No No
1Y77_J (116521) DNA-directed RNA polymerases I, II, and III subunit RPABC5 RNA polymerase, RNA polymerase, RNA polymerase 4.5Å No No
2B63_J (127929) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2B8K_J (128089) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 4.15Å No No
2E2H_J (131991) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.95Å No No
2E2I_J (132004) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.4Å No No
2E2J_J (132017) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.5Å No No
2JA5_J (138171) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2JA6_J (138187) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 4Å No No
2JA7_V (138219) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2JA7_J (138203) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2JA8_J (138235) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2NVQ_J (138644) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 2.9Å No No
2NVT_J (138657) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.36Å No No
2NVX_J (138677) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.6Å Yes No
2NVY_J (138690) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.4Å No No
2NVZ_J (138703) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 4.2Å No No
2R7Z_J (151664) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2R92_J (151751) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.8Å No No
2R93_J (151760) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 4Å No No
2VUM_J (153554) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.4Å No No
2YU9_J (140074) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.4Å No No
3CQZ_J (156933) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 2.8Å No No
3FKI_J (3410403) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.8Å No No
3GTG_J (3440274) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.78Å No No
3GTJ_J (3440302) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.4Å No No
3GTK_J (3440327) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.8Å No No
3GTL_J (3440352) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.38Å No No
3GTM_J (3440377) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.8Å No No
3GTO_J (3440407) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 4Å No No
3GTP_J (3440432) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.9Å No No
3GTQ_J (3440457) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.8Å No No
3H3V_K (3450169) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 4Å No No
3HOU_J (4003651) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.2Å No No
3HOU_V (4220671) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.2Å No No
3HOV_J (4062936) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.5Å No No
3HOW_J (4177257) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.6Å No No
3HOX_J (4046397) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.65Å No No
3HOY_J (4227550) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.4Å No No
3HOZ_J (4235470) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.65Å No No
3I4M_J (4243395) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.7Å No No
3I4N_J (4224678) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.9Å No No
3K1F_J (3490616) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 4.3Å No No
3K7A_J (3500012) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.8Å No No
3M3Y_J (3540490) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.18Å No No
3M4O_J (3540537) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.57Å No No
3PO2_J (3670473) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.3Å No No
3PO3_J (3670497) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.3Å No No
3QT1_J (3690462) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 4.3Å No No
3RZD_J (3700489) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.29Å Yes No
3RZO_J (3700513) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3Å No No
3S14_J (3700553) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 2.84Å No No
3S15_J (3700573) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.3Å No No
3S16_J (3700593) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.24Å No No
3S17_J (3700613) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.17Å Yes No
3S1M_J (3700646) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.13Å No No
3S1N_J (3700666) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.1Å No No
3S1Q_J (3700686) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.3Å No No
3S1R_J (3700706) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.2Å No No
3S2D_J (3700750) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.19Å No No
3S2H_J (3700770) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, UNMATCHED 3.29Å No No
4A3C_J (4258512) DNA-directed RNA polymerases I, II, and III subunit RPABC5 DNA/RNA-binding 3-helical bundle, RNA polymerase subunit RPB10, RNA polymerase subunit RPB10 3.5Å Yes No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score