Molecular Target Synopsis
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NPR2 (P20594) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) GUCY1B1 (Q02153) GUCY1A1 (Q02108) HUMAN 4NI2_B 44 1.0E-36 1.9Å - 2014-04-16
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_E 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) cya (P9WQ35) - 4P2F_A 40.09 2.0E-37 2.05Å - 2014-09-17
Adenylate and Guanylate cyclase catalytic domain (94%) (view alignment) GUCY1A1 (Q02108) GUCY1B1 (Q02153) HUMAN 4NI2_A 47.49 7.0E-39 1.9Å - 2014-04-16
Adenylate and Guanylate cyclase catalytic domain (94%) (view alignment) GUCY1A1 (Q02108) GUCY1B1 (Q02153) HUMAN 3UVJ_A 47.49 9.0E-39 2.08Å - 2011-12-28
Receptor family ligand binding region (100%) (view alignment) Npr1 (P18910) - NORWAY RAT 1DP4_A 43.96 2.0E-97 2Å NAG 2000-07-12
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_K 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) cya (P9WQ35) - 4P2M_A 39.63 2.0E-36 2.7Å - 2014-09-17
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_A 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_A 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_J 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A060H1D7) - AQUATIC FUNGUS 6AOA_A 40.96 7.0E-35 1.4Å - 2017-11-22
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_G 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) cya (P9WQ35) - 4P2X_A 39.63 2.0E-36 2.4Å - 2014-09-17
Adenylate and Guanylate cyclase catalytic domain (98%) (view alignment) (Q5YLC2) - 3ET6_A 48.39 2.0E-42 2.55Å - 2008-10-14
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_D 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_K 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_B 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A060H1D7) - AQUATIC FUNGUS 6AOB_B 42.02 7.0E-37 1.7Å - 2017-11-22
Receptor family ligand binding region (100%) (view alignment) Npr1 (P18910) Nppa (P01161) NORWAY RAT 1T34_A 43.96 2.0E-97 2.95Å NAG 2004-08-03
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) cya (P9WQ35) - 4P2X_B 39.63 2.0E-36 2.4Å - 2014-09-17
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_F 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_I 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) GUCY1B1 (Q02153) - HUMAN 2WZ1_A 44 1.0E-36 1.63Å - 2009-12-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_D 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) GUCY1B1 (Q02153) - HUMAN 2WZ1_B 44 1.0E-36 1.63Å - 2009-12-01
Receptor family ligand binding region (100%) (view alignment) Npr1 (P18910) Nppa (P01161) NORWAY RAT 1T34_B 43.96 2.0E-97 2.95Å NAG 2004-08-03
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_B 41.59 1.0E-39 2.7Å ONM 2017-11-01
Receptor family ligand binding region (100%) (view alignment) Npr1 (P18910) - RAT 3A3K_B 43.96 2.0E-97 2.5Å NAG 2010-03-16
Receptor family ligand binding region (100%) (view alignment) Npr1 (P18910) - RAT 3A3K_A 43.96 2.0E-97 2.5Å NAG 2010-03-16
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_D 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_C 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_J 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_J 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) GUCY1B1 (Q02153) GUCY1A1 (Q02108) HUMAN 3UVJ_D 43 2.0E-34 2.08Å - 2011-12-28
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_I 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_N 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_K 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_H 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_M 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_P 40.43 1.0E-34 2.24Å T99 2018-06-06
Receptor family ligand binding region (100%) (view alignment) Npr1 (P18910) - NORWAY RAT 1DP4_C 43.96 2.0E-97 2Å NAG 2000-07-12
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_L 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_O 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (98%) (view alignment) (Q5YLC2) - 3ET6_B 48.39 2.0E-42 2.55Å - 2008-10-14
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_I 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_H 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A060H1D7) - AQUATIC FUNGUS 6AOB_A 42.02 7.0E-37 1.7Å TLA 2017-11-22
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_F 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_F 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) GUCY1B1 (Q02153) GUCY1A1 (Q02108) HUMAN 3UVJ_B 43 2.0E-34 2.08Å - 2011-12-28
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_B 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_E 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_E 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_A 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5K_C 41.59 1.0E-39 3.2Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_C 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) cya (P9WQ35) - 1YK9_A 39.79 2.0E-33 2.65Å - 2006-01-24
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A060H1D7) - AQUATIC FUNGUS 6AO9_A 42.02 7.0E-37 1.13Å - 2017-11-22
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (X8CHM4) - 5O5L_G 41.59 1.0E-39 2.7Å ONM 2017-11-01
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_H 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) (A0A1Y2HEJ3) - 5OYH_G 40.43 1.0E-34 2.24Å T99 2018-06-06
Adenylate and Guanylate cyclase catalytic domain (94%) (view alignment) GUCY1A1 (Q02108) GUCY1B1 (Q02153) HUMAN 3UVJ_C 47.49 9.0E-39 2.08Å - 2011-12-28
Adenylate and Guanylate cyclase catalytic domain (100%) (view alignment) cya (P9WQ35) - 4P2M_B 39.63 2.0E-36 2.7Å - 2014-09-17