RAB3A (P20336) - Overview - Molecular Target Synopsis
RAB3A, Ras-related protein Rab-3A
Also Known as RAB3A_HUMAN, RAB3A
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: RAB3A is active in the following subcellular-locations: cell membrane.
GO terms: RAB3A is active in the following subcellular-locations: acrosomal vesicle, anchored component of synaptic vesicle membrane, axon, clathrin-sculpted acetylcholine transport vesicle membrane, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, clathrin-sculpted glutamate transport vesicle membrane, clathrin-sculpted monoamine transport vesicle membrane, cytosol, endosome, extracellular vesicle, plasma membrane, presynaptic active zone, protein-containing complex, secretory granule membrane, synaptic vesicle, terminal bouton, vesicle.