Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

CATHL3 (P19661) - Overview - Molecular Target Synopsis

Protein


CATHL3, Cathelicidin-3
UniProt P19661

Also Known as CTHL3_BOVIN, CATHL3, BAC7

Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.

4JWC
10 RESIDUE FRAGMENT OF
CATHELICIDIN-3
IN THE STRUCTURE OF
CRYSTAL STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF E.COLI DNAK IN COMPLEX WITH BOVINE BAC7(1-16)
RCSB/PDB
Inspect Structure
See all 3D Structures for CATHL3

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
190P19661-1

Sub-cellular localization


UniProt: CATHL3 is active in the following subcellular-locations: secreted.
GO terms: CATHL3 is active in the following subcellular-locations: extracellular space, specific granule.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project CATHL3 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For CATHL3 there are:
2 structures (4 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis