ATP4B, Potassium-transporting ATPase subunit beta
Also Known as
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. Composed of two subunits: alpha (catalytic) and beta.
Isoforms / Transcripts (Protein Coding)
UniProt: ATP4B is active in the following subcellular-locations: cell membrane.
GO terms: ATP4B is active in the following subcellular-locations: sodium.
Gene Copy Number Variation
In COSMIC - Cell Lines Project ATP4B has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)
Screening and Chemistry
ATP4B has been screened with 438 compounds (496 bioactivities), 60 compounds have bioactivities that show binding affinity of <= 500nM (60 bioactivities). (see details)